Read this Original Article on the association of intrapatient tacrolimus variability & concentration-to-dose ratio w/outcomes in pediatric kidney transplantation. #OpenAccess .

Non-English language preference is assoc w/health disparities in pediatrics, including delayed care, adverse events, & increased risk of mortality. Read this Research Letter on language preference & acute care utilization after pediatric kidney transplant.

High panel reactive antibody titers are challenging for patients undergoing kidney transplantation. Read this Original Article on anti-CD19 chimeric antigen receptor T-cell therapy in a highly sensitized patient w/focal & segmental glomerulosclerosis.

AKI affects 30% of hospitalized pediatric patients, w/high mortality in neonates. Read this Original Article on continuous kidney replacement therapy w/CARPEDIEM® of premature & low birth weight neonates from the French registry.

The efficacy of glucocorticoid (GC) in the management of immunoglobulin A nephropathy (IgAN) remains highly controversial. Read this Original Article on the efficacy & kidney outcomes of GC in treating pediatric IgAN.

Fluid accumulation (FA) is associated w/morbidity & mortality in intensive care. Read this Original Article on the sources of FA in critically ill children admitted to pediatric intensive care.

The Spalt-like transcription factor 1 gene is essential for kidney development. Pathogenic SALL1 variants cause Townes-Brocks syndrome 1. Read this Original Article on clinical characteristics of patients w/SALL1-related disorders in Japan. #OpenAccess .

Preterm infants' kidneys are exposed to exogenous factors that affect their maturation & development, & they are at higher risk of developing nephrocalcinosis (NC). Read this Original Article on incidence, risk factors, & outcomes of NC in preterm infants.

Pediatric nephrologists face challenging situations when decision-making is difficult. Read this Educational Review of key ethical principles in ethical dilemmas, that proposes a stepwise decision-making framework. Free access this month.

Hispanics, the fastest growing minority in the USA, suffer from high CKD burden. Read this Original Article on healthcare access barriers for Hispanic pediatric nephrology patients. Part of a KICK (Kidney Initiative in Community Kids) study. #OpenAccess .

Gut microbiota are key regulators of systemic health, influencing kidney development, function, & blood pressure regulation. Read this Review of the role of microbiota-derived short-chain fatty acids in kidney physiology & development. #OpenAccess .

Read this Original Article on whether the PrisMax & CARPEDIEM hemofiltration & hemodialysis devices can reliably deliver ultrafiltration control that is sufficiently precise to treat infants. #OpenAccess .

Dialytic sodium removal (DSR) is an important parameter of peritoneal dialysis (PD) adequacy. Read this Original Article on DSR of children w/AKI on a standard acute PD prescription compared to children on continuous flow PD. #OpenAccess .

Hemoadsorption devices represent a significant advancement in extracorporeal organ support therapies, enabling the targeted removal of molecules that are not cleared by conventional kidney replacement therapies. Read this Educational Review for more.

Kidney protection in children has relied on angiotensin-converting enzyme inhibitors & angiotensin receptor blockers, which present significant limitations. Read this Review of sodium-glucose cotransporter 2 inhibitors for kidney protection in children.

Children w/cancer have had significant improvements in cure rates, but survivors have been left w/long-term adverse effects, including nephrotoxicity. Read this Educ Review of nephrotoxicity of immunotherapy & therapies used to treat pediatric cancer.

Chronic non-communicable diseases pose a significant global health challenge, w/the human gut microbiota emerging as a key player in several (patho) physiological functions. Read this Review of the gut-kidney axis in pediatric & adult CKD. #OpenAccess .

Prematurity is linked to kidney dysfunction, & children born very preterm are at particular risk due to interrupted nephrogenesis. Read this Original Article on early detection of kidney impairment in children born very preterm. #OpenAccess .

Read these Clinical Insights into a 15-yr-old boy w/severe septic shock & multiple organ failure, & the effect of therapeutic plasma exchange on amoxicillin, clindamycin, midazolam, & morphine pharmacokinetics. #OpenAccess .

Read this Original Article on assessing fluid status in pediatric patients on peritoneal dialysis by combining ultrasonography & bioimpedance spectroscopy (BIS): a multimodal diagnostic approach. #OpenAccess .