Lianyong Wang
@LianyongW
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Assistant Professor at Northeastern University, Boston. Excited about photosynthesis, chloroplast function, and algal CO2 sensing.
Boston
Joined June 2022
Congrats to the team including @Shanhe_PU, @lsquared64, @almcalvo, @lianyongw, @Ashwani_Rai1, @brangwynnelab, and Ned Wingreen! Grateful to @HHMINEWS , @NSF, @DOEScience, @NIH, and @HFSP for supporting this interdisciplinary project.
Algal pyrenoids—condensates that mediate ~1/3 of Earth’s CO2 fixation—change size and number as cells divide. Our data suggest a simple control mechanism: a kinase that continuously ejects material from the condensate! ☀️🌍🔬💧 #Biophysics #Photosynthesis
https://t.co/kT5C14FXXI
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Out today on @PlantCellEnvir our latest work on the study of Chlamydomonas compartment-specific Ca2+ dynamics!🔬 A big thank to all the people involved and @EMBO for the Scientific Exchange Grant that funded my visit to @thembauk! 🇬🇧🇮🇹🙏🏻 @lab_costa, @GLWheeler2 and @BallottariM.
Excited to share our new @PlantCellEnvir work! This study highlights how compartment-specific Ca²⁺ transients in Chlamydomonas are intricately linked to external environmental cues. By @Matteo_Pivato and @BallottariM, with @GLWheeler2 & @lab_costa labs https://t.co/5Viw8OZEKp
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We performed subtomogram averaging on complexes from >3 MDa to ~200 kDa, including 80S ribosomes, Rubisco, clathrin, microtubules, ATP synthase photosystem II, and nucleosomes. Most density maps achieved sub-nanometer resolution!🔬✨ #CryoET #StructuralBiology #VisualProteomics
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Watch this movie 🔬🍀 In a sugar-deprived condition, a chloroplast bud is released. Beautifully captured using chloroplast stroma marker RBCS-GFP (magenta) and the inner envelope marker KEA1-mRFP (green) An excellent recent article published @eLife
https://t.co/dGS0tf7I6k
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We are excited to share 71,700 new #Chlamy mutants from the CLiP2 collection pre-publication! Nearly-saturating genome coverage. Please note: new background strain, mating type, and antibiotic resistance. Read: https://t.co/t0SUtH26rP Search and order: https://t.co/4dGxCXXrmt
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Want to make thylakoids traverse a pyrenoid matrix? Read here to find out how! Excited that this fantastic collaborative story is now published, congrats and a big thank you to all involved @JonikasLab, @pituvilarnadal, @JinkersonLab and Sam Zeeman’s lab.
nature.com
Nature Plants - Two algal proteins, MITH1 and SAGA1, play key roles in formation of membranes that deliver CO2 to the pyrenoid, a CO2-concentrating organelle. Their discovery marks a key milestone...
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Excited to share our latest preprint! Proteomic analysis of the pyrenoid-traversing membranes of Chlamydomonas reinhardtii reveals novel components https://t.co/k8w79anycc
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I am pleased to announce the opportunities in my lab for PhD candidates interested in exploring CO2 sensing in microalgae, the regulation of photosynthesis, the roles of novel chloroplast punctate structures, and chloroplast function. If you or someone you know is curious about
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A blueprint of the diatom pyrenoid reveals a Rubisco encapsulating protein Shell is critical for CO2 fixation. Is it essential for global NPP? Congrats to @OnyouNam,@james_r_barrett,@ItsCarolineMck,@JNB_lab + great collab with @DemulderManon,@bengeliscious. https://t.co/gPwPLtylBR
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The final version of our PyShell🥧🐚 paper is now online @CellCellPress. Check out how diatoms soak up 20% of the Earth's #CO2!🌏 📜 https://t.co/vm0A20XKaS Brilliant work by @DemulderManon, @Jorgendottir, Ginga, Aki, Giovanni, Genji, Yusuke, and all the rest of our collabs 🤗
Meet the PyShell!🥧🐚 Diatom pyrenoids fix up to 20% of the Earth's #CO2🌏. We discovered that their Rubisco is encased in a tight protein lattice that is essential for efficient carbon fixation and cell growth🌱 Super excited to share our new preprint📜: https://t.co/zkYHHLbvBy
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Excited to share our latest preprint! Biogenesis, engineering and function of membranes in the CO2-fixing pyrenoid https://t.co/NAxQmBXSky
biorxiv.org
Approximately one-third of global CO2 assimilation is performed by the pyrenoid[1][1], a liquid-like organelle found in most algae and some plants[2][2]. Specialized membranes are hypothesized to...
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CsLinker: an algal pyrenoid assembly protein that binds the RbcL, complements across 800 My of evolution and phase separates plant Rubisco. Very excited to share this work by @james_r_barrett, @JNB_lab, @mjplevin, @BPSIYork, @McCormick_Lab. @JonikasLab
https://t.co/8DLApHvle3
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Access to the Antenna System of Photosystem I via Single-Molecule Excitation–Emission Spectroscopy | The Journal of Physical Chemistry B https://t.co/0LTcMGGWfT My best work so far!
pubs.acs.org
In the development of single-molecule spectroscopy, the simultaneous detection of the excitation and emission spectra has been limited. The fluorescence excitation spectrum based on background-free...
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Congratulations @PerrinAbi and team for developing this new resource. CyanoTag: Discovery of protein function facilitated by high-throughput endogenous tagging in a photosynthetic prokaryote https://t.co/yAHDzpoANN . Explore the data here: https://t.co/8xMqssQcDN
@Algae_UK #algae
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Fantastic work! Another step closer to engineering plant pyrenoids🤩
A great way to end to the week, our starchy saga is now out in PNAS.
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We have arrived at the top of the countdown! Our #1 post of the year is @LongLab's TED Talk! Watch the talk, Can we Hack Photosynthesis to Feed the World: https://t.co/Epn3a0EUJ0 or read about the talk here: https://t.co/9qyLBdO6Kr
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Congrats @KafriMoshe and team including @WPatena, @LianyongW, @ASirkejyan, @AsaelRoichman, @clairemcwhite, @MartinWuhr! Systematic identification and characterization of novel genes in the regulation and biogenesis of photosynthetic machinery. https://t.co/pkV1HBUbKe
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Now published online! A Chloroplast Protein Atlas Reveals Punctate Structures and Spatial Organization of Biosynthetic Pathways https://t.co/O9rFhjnBXr Congratulations, @LianyongW, Weronika Patena, @clairemcwhite, @VinhTTon, Jianping Hu, @onishilab, and team!
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Excited to share our latest preprint: Systematic identification and characterization of novel genes in the regulation and biogenesis of photosynthetic machinery https://t.co/vR8tgsO0Iw Proteomic data for 100 mutants reveal functions of novel genes with roles in photosynthesis!
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The new Chlamydomonas genome version is here with many improvements! The Chlamydomonas Genome Project, version 6: reference assemblies for mating type plus and minus strains reveal extensive structural mutation in the laboratory | bioRxiv
biorxiv.org
Five versions of the Chlamydomonas reinhardtii reference genome have been produced over the last two decades. Here we present version 6, bringing significant advances in assembly quality and struct...
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