John Keane
@keane_jpm
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Consultant Urologist University Hospital Waterford and UPMC Aut Even
Joined March 2013
1/2 Just published in @JAMAOnc: 15-year outcomes of Active Monitoring, Surgery, and Radiotherapy for cribriform-positive and cribriform-negative prostate cancer in the ProtecT trial. Secondary analysis based on centralised biopsy review🔬 Article:
jamanetwork.com
This secondary analysis of the PROTECT randomized clinical trial assesses the association between cribriform-positive and cribriform-negative prostate cancer and risk of metastasis in patients who...
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💊 Recurrent cystitis? Antibiotics aren’t always needed! Women should know about evidence-based, antibiotic-sparing options like: 🔹 Xyloglucan + Hibiscus + Propolis 🔹 Centaurii herba, Levistici radix & Rosmarini folium #WomensHealth #EAUGuidelines #UroUTI
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JUST IN: Tar200 now @US_FDA approved based on SunRise-1 phase 2 trial in BCG unresponsive NMIBC. -Intravesical form of Gemcitabine - CR: 82.4%/grade ≥3 AE 12.9% - DFS 70.2% at 12m - 51% of CRs with DOR ≥ 12 months.
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🇭🇺✨ Dominik Szoboszlai’s free kick against Arsenal from this angle is incredible. 😍 https://t.co/PczzXquq4r
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On Friday, @HSELive published the 2023-2024 Annual Report for @UHW_Waterford South East Cancer Services, highlighting the continued focus on providing safe, high-quality care to patients in Waterford, Wexford, South Tipperary and Carlow/Kilkenny.
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UPMC is proud to launch our upgraded PET CT scanner at UPMC Whitfield Hospital—offering faster access & enhanced diagnostic accuracy for patients across Waterford and the South East. Congratulations to our Radiology team for advancing care where it’s needed most.
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Very interesting study: disrupted gut microbiome in fibromyalgia (mouse & human data) supports the idea that improving gut microbe conditions may help. You can wait for more or just consume 1-3 servings low sugar fermented food daily per other findings
cell.com
Cai et al. revealed that transplanting gut microbiota from women with fibromyalgia—a chronic widespread pain condition of unknown etiology—into mice induces pain. It also induces phenotypes commonly...
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Even if you’ve watched it 100 times already just watch it again
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The Role of Baseline Prostate-specific Antigen Value Prior to Age 60 in Predicting Lethal Prostate Cancer: Analysis of a Contemporary North American Cohort by @FinatiMarco, Matthew Davis et al https://t.co/RAfvMOTaf8
#UroSoMe #MedTwitter #ProstateCancer #PCa
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In patients with muscle-invasive bladder cancer, extended lymphadenectomy did not improve disease-free or overall survival as compared with the standard procedure and was associated with higher morbidity and mortality. Full SWOG S1011 trial results: https://t.co/mYGY3Zd2MX
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🚨Standard or Extended Lymphadenectomy for Muscle-Invasive Bladder Cancer🚨 👏Landmark trial in urology in @NEJM 😷592 patients randomized 🗓️Median f/u 6.1 years 👉No difference in... 5-year disease-free survival (60% v 56%) 5-year overall survival (63% v 59%)
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Transperineal biopsy lowers the risk of infectious complications while maintaining a similar rate of prostate cancer detection compared with transrectal biopsy, according to data from the PREVENT trial. @jimhumd @EdwardSchaeffer @WCMUrology @NM_Urology
https://t.co/ndoinO8PhK
urologytimes.com
No patients in the transperineal cohort experienced an infection, compared with 1.6% of patients in the transrectal cohort.
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Overall Survival with Adjuvant Pembrolizumab in Renal-Cell Carcinoma | New England Journal of Medicine
nejm.org
Adjuvant pembrolizumab therapy after surgery for renal-cell carcinoma was approved on the basis of a significant improvement in disease-free survival in the KEYNOTE-564 trial. Whether the results r...
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Cytoreductive nephrectomy in the era of immune checkpoint inhibitors: a U.S. FDA pooled analysis
academic.oup.com
AbstractBackground. This pooled analysis of patient-level data from trials evaluated the clinical outcomes of patients with metastatic renal cell carcinoma
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Enfortumab Vedotin and Pembrolizumab in Untreated Advanced Urothelial Cancer | NEJM
nejm.org
No treatment has surpassed platinum-based chemotherapy in improving overall survival in patients with previously untreated locally advanced or metastatic urothelial carcinoma. We conducted a phase ...
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Transperineal Versus Transrectal Magnetic Resonance Imaging–targeted and Systematic Prostate Biopsy to Prevent Infectious Complications: The PREVENT Randomized Trial - ScienceDirect
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UHW are currently recruiting for a Clinical Nurse Specialist (Urology). Please click on the link below for further information. #Recruiting #JobAlert #JobVacancies #HSE #SSWHG #UHW
https://t.co/TplBImVCDf
rezoomo.com
University Hospital Waterford is looking to fill the role of 23UHWNU0412 Clinical Nurse Specialist (Urology) in Waterford. Apply today!
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AT LAST, we can accurately advise men likely result of prostate surgery for urinary symptoms. This @EurUrolFocus paper is the UPSTREAM model for how @EauGuidelines clinic tests predict outcome. The algorithm gives patients best chance of improving. https://t.co/L54va5dn4Q.
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