The third Intensive Care Bundle with Blood Pressure Reduction in Acute Cerebral Haemorrhage Trial (INTERACT3): an international, stepped wedge cluster randomised controlled trial https://t.co/8iAMwCywCe

El control rápido de la presión arterial es crucial en ICH. Ensayos INTERACT2, ATACH2 e INTERACT3 muestran que reducir la PAS a 130–140 mmHg dentro de la primera hora mejora la función sin aumentar isquemia ni mortalidad. Nuestra última publicación https://t.co/p83l0crEAg

#MondayTip 🩸ICH Dawn of a New Era 🌎"ICH is a devastating disease, causing high rates of death, disability, and suffering across the world" 🎉2023 was a good year in ICH field: INTERACT3 ENRICH ANNEXa-1 💪and 2024 is not disappointing: INTERACT4 SWITCH 🔗 https://t.co/2OOb2Xh0Lg

INTERACT3 shows that care bundle addressing BP, glucose, temp leads to improved outcomes among patients with ICH with NNT of 35. #ESOC2023

Care Bundle Improves Outcome in ICH: INTERACT3 https://t.co/au7OvAYAkF

#INTERACT3 implemented an intensive care bundle with BP reduction & management of hyperglycaemia, pyrexia & abnormal anticoagulation for #ICH patients in a stepped-wedge cluster #RCT Compared to standard care, the bundle improved functional outcome in #ICH patients #ESOC2023 👇

INTERACT3 provides strong support to our ongoing implementation of the ABC bundle for ICH in the UK, we hope to expand the project beyond the North of England phase to bring benefits to even more of our ICH patients in the UK and beyond. #ESOC2023

🔴 Treatment for intracerebral hemorrhage: Dawn of a new era #2024Review #openaccess 🔸🎉2023 was a good year in ICH field: INTERACT3 ENRICH ANNEXa-1 🔸💪and 2024 is not disappointing: INTERACT4 SWITCH https://t.co/Ux5Q4H2Lz2 #Cardiology

Exciting results from INTERACT3 about using an ICH bundle for rapid management of ICH patients. #ESOC23. More data to corroborate using protocols such as the ABC-ICH bundle.

First Journal Club presentation ✅ Results of the INTERACT3 trial: https://t.co/PWf0XxyqAg #Neurology

Care Bundle Improves Outcome in ICH: INTERACT3 https://t.co/ebaovCLFAw

My PGY2’s (@amayzhanggg ) first ICU journal club of the year on #INTERACT3 🧠 & she did me proud! 1 down! 🥹 #PharmICU @ASHPOfficial

INTERACT3 looked at the rapid blood preasure reduction, anti-pyrexia treatment and reversal of anticoagulation in 7036 patients with acute ICH ➡️ and showed strong effects on 90-Day outcome (0.8, 0.7-0.9). NNT = 35. Congratulations to all the investigators! #ESOC2023

A second positive ICH trial in one session! A care bundle approach improved outcome for ICH patients in INTERACT3. Another fantastic result for ICH care! #esoc2023

INTERACT3 Felicidades maestros @VaneNigenda @AntonioArauz2 🙌👏👏

The prospective, international INTERACT3 results support a bundled ICH protocol to manage ⬆️🌡️, ⬆️BG, abnormal 🩸, and early intensive ⬇️BP to ⬆️🚶status + ⬇️☠️ at 6 months. However, the results may lack external validity due to the studied population. #EMRx #TwitteRx

The INTERACT3 cluster randomized trial: Implementation of a care bundle improved functional outcome, reduced mortality, and had fewer serious adverse events in patients with intracerebral hemorrhage. #ESOC2023 #ESOC @ESOstroke

The 3rd Intensive Care Bundle w Blood Pressure Reduction in Acute Cerebral Haemorrhage Trial (INTERACT3): A stepped wedge cluster RCT looked at rapid BP reduction, anti-pyrexia Rx & reversal of AC in 7K pts w ICH ➡️ Strong effects on 90-Day outcome (0.8, 0.9)& NNT=35.

INTERACT3 will be presented at #ESOC2023! Find out how they randomised clusters of hospitals instead of individual patients. Prof Craig Anderson @georgeinstitute gives a preview: https://t.co/g8GMAnZjBQ Register: https://t.co/YGVkMVfOfb #stroke #strokeresearch #StrokeTwitter