Does testing error underlie liquid biopsy discordance? "Bake-off" from
@AstraZeneca
suggests that, in the wild world of plasma NGS assays, technical factors impact assay variability more than we realize:
@geoff_oxnard
@AstraZeneca
Really nice analysis by
@AstraZeneca
and commentary by
@geoff_oxnard
. Not sure, but presumably the plasma assays were not optimized for early-stage detection (a known challenging application for ctDNA, with emerging solutions).