Check out our new paper in the European Journal of Paediatric Neurology @EPNSnews w/@Laura_Simons, @Inge__Timmers , @_edinaszabo & David Borsook that found altered brain function in adolescents w/ #endometriosis associated #pain. https://t.co/BzvPZR0X2o 🧵 on key results:
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1. Less functional connectivity b/t the rt anterior insula & pain-related regions; 2. Anterior insula & cerebellum connectivity was linked to greater pain intensity; 3. Alterations in pain regulatory pathways in endo; 4. Brain changes correlated w/state anxiety & fear of pain.
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@suzieassanie, another amazing colleague & mentor, conducted the initial groundbreaking neuroimaging studies in endo pain in adults. Some of our findings overlap with her results & some are distinct in the adolescent cohort suggesting the need to explore age-related differences.
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