BioOrgNMR Lab
@bioorgnmr
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Joined December 2018
Our latest publication on Wiley Small Structures "Clustering Zwitterionic Amino Acids at the Upper Rim of Cone Calix[4]arene Triggers the Selective Recognition of Gram-Negative Bacterial Envelope" https://t.co/Qo2c6jFYsC
@unimib @BtBsUNIMIB @Chris_Airoldi @AlexPalmioli @unipr
onlinelibrary.wiley.com
By Saturation Transfer Difference Nuclear Magnetic Resonance studies, calix[4]arenes bearing zwitterionic amino acids are identified as selective ligands for Gram-negatives over Gram-positives or...
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An NMR Toolkit to Probe Amyloid Oligomer Inhibition in Neurodegenerative Diseases: From Ligand Screening to Dissecting Binding Topology and Mechanisms of Action (@AlexPalmioli and @Chris_Airoldi at @bioorgnmr, @BtBsUNIMIB, @unimib) #NMRChat
chemistry-europe.onlinelibrary.wiley.com
NMR-based molecular recognition studies allow to “fish” ligands of amyloid aggregates and characterize the structural determinant of the binding, shedding light on amyloid inhibitors mechanism of...
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An NMR Toolkit to Probe Amyloid Oligomer Inhibition in Neurodegenerative Diseases: From Ligand Screening to Dissecting Binding Topology and Mechanisms of Action https://t.co/mFzLTkmv7P
@unimib @BtBsUNIMIB @Chris_Airoldi @AlexPalmioli
chemistry-europe.onlinelibrary.wiley.com
NMR-based molecular recognition studies allow to “fish” ligands of amyloid aggregates and characterize the structural determinant of the binding, shedding light on amyloid inhibitors mechanism of...
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Mechanistic and Structural Insights on Difluoromethyl-1,3,4-Oxadiazole Inhibitors of HDAC6 https://t.co/yuHHlVXs0y…
@unimib @BtBsUNIMIB @Chris_Airoldi @AlexPalmioli through a nice collaboration with Research and Development, Italfarmaco Group
mdpi.com
International Journal of Molecular Sciences, an international, peer-reviewed Open Access journal.
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Cell-Free and In Vivo Characterization of the Inhibitory Activity of Lavado Cocoa Flavanols on the Amyloid Protein Ataxin-3: Toward New Approaches against Spinocerebellar Ataxia Type 3 https://t.co/zIawZ0Rj9M
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📌 Aperte le iscrizioni per la 𝐏𝐫𝐢𝐦𝐚 𝐒𝐜𝐮𝐨𝐥𝐚 𝐍𝐚𝐳𝐢𝐨𝐧𝐚𝐥𝐞 𝐝𝐢 𝐑𝐢𝐬𝐨𝐧𝐚𝐧𝐳𝐚 𝐌𝐚𝐠𝐧𝐞𝐭𝐢𝐜𝐚 𝐍𝐮𝐜𝐥𝐞𝐚𝐫𝐞 𝐩𝐞𝐫 𝐥𝐨 𝐬𝐭𝐮𝐝𝐢𝐨 𝐝𝐢 𝐩𝐢𝐜𝐜𝐨𝐥𝐞 𝐦𝐨𝐥𝐞𝐜𝐨𝐥𝐞 𝐨𝐫𝐠𝐚𝐧𝐢𝐜𝐡𝐞 🗓️ 19-20/02/24 🚧 Deadline: 9/02/24 🔗 https://t.co/GiI55hWvR2
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Adjuvant Effect of Cinnamon Polyphenolic Components in Colorectal Cancer Cell Lines https://t.co/3HbWqBVoXQ
@unimib @BtBsUNIMIB
@Chris_Airoldi @AlexPalmioli
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The first untargeted metabolomic study of Antarctic soils by combining NMR and MS... proud of us!!! #pnra
https://t.co/zL2bHPytIu
@unimib @BtBsUNIMIB @Chris_Airoldi @AlexPalmioli @c_ciaramelli @ZucconiGalli @maubri78 @solveigtosi
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Beer might have some surprising health benefits. @Chris_Airoldi, @AlexPalmioli and colleagues at @unimib found that compounds extracted from hops could help protect against Alzheimer’s disease. https://t.co/q0jltaWyRK
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Some people love the distinct, bitter taste of the hops used to flavor beer and others hate it. Some of the compounds in hop flowers could help prevent Alzheimer’s disease. New in @ACSChemNeurosci: https://t.co/hVNTCBi2YV
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Conformationally Restricted β‐Sheet Breaker Peptides Incorporating Cyclic α‐Methylisoserine Sulfamidates https://t.co/LDxF7JPga2
@unimib @BtBsUNIMIB @Chris_Airoldi
chemistry-europe.onlinelibrary.wiley.com
The use of a cyclic sulfamidate moiety as a β-sheet breaker element is proposed for the first time. The sulfamidate effectively locks the peptide secondary structure in a novel rigid turn both in...
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Luppolo, #birra e prevenzione 🍺🧠 Sul New York Post, lo studio di Cristina Airoldi, Alessandro Palmioli e altri: i composti del luppolo potrebbero servire come base per i "nutraceutici" contro lo sviluppo del Morbo di #Alzheimers! @nypost
https://t.co/kMMqzqTmhw
nypost.com
Researchers tested hop flower extracts that are found in beer to see how well they would help to prevent brain protein clumping, which can lead to the disease.
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Alzheimer’s Disease Prevention through Natural Compounds: Cell-Free, In Vitro, and In Vivo Dissection of Hop (Humulus lupulus L.) Multitarget Activity https://t.co/ZPbZoX9aYt
@unimib @BtBsUNIMIB @Chris_Airoldi @AlexPalmioli @ACSChemNeurosci #bioNMR #natural_compounds
pubs.acs.org
The relevant social and economic costs associated with aging and neurodegenerative diseases, particularly Alzheimer’s disease (AD), entail considerable efforts to develop effective preventive and...
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Italian-French International Conference on Magnetic Resonance Jointly organized by the GIDRM and GERM 27-30 September 2022, Milan @BtBsUNIMIB
@unimib
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NMR-based Ligand–Receptor Interaction Studies under Conventional and Unconventional Conditions https://t.co/188iskx9Eb
@unimib @BtBsUNIMIB @Chris_Airoldi @AlexPalmioli @c_ciaramelli @RoySocChem
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