Hereticslave
@ashishchauhan__
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Physician scientist, Gastroenterologist by training (PGI Chandigarh, AIIMS New Delhi). A geek, a heretic and humanist
Shimla, India
Joined October 2016
🧵 on article from @ICMRDELHI Study @HepatologyPGI @AmJGastro Can early empirical antifungals really change outcomes in ACLF with suspected invasive fungal infection (IFI)? 🤔 @AASLDtweets @AmerGastroAssn @EASLnews @EASLedu @INASL_Liver @APASLnews @BASLedu @LiverFellow
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Q: What's the harm in a little FFP? #cirrhosis A: The potential to *double* the portal pressure https://t.co/ZZe0rsC784 What FFP doesnt do:⬆️coagulation function What FFP does do: ⬆️blood volume/pressure Why this matters: pressure causes variceal bleeding #livertwitter
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New online! Pharmacological management of obesity
nature.com
Nature Reviews Gastroenterology & Hepatology - Pharmacological management of obesity
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Non-celiac gluten sensitivity arises through several potential mechanisms including psychological factors (e.g., nocebo effect) and FODMAP effect (fructans). https://t.co/KexS3Kzcrw
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The Mediterranean Diet for Irritable Bowel Syndrome: an RCT: Annals of Internal Medicine. Great new evidence supporting MD for IBS @RomeFoundation @umichmedicine
acpjournals.org
Background: Patients with irritable bowel syndrome (IBS) frequently seek dietary advice, but few evidence-based options exist. Major societal guidelines recommend traditional dietary advice (TDA) as...
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Haris Rauf conceded 50 runs in 3.4 overs Rest of the Pakistan bowlers conceded only 100 in 16 overs. That’s where Pakistan lost the game.
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New from us published in @APandT Biochemical non-response to Obeticholic acid (OCA) is associated with improved event-free survival in PBC - a multicentre study. Further evidence as to why @US_FDA and @EMA_News may not have made the right decision. https://t.co/GhyB6452Dl
onlinelibrary.wiley.com
In a multi-centre study of obeticholic acid in primary biliary cholangitis, 45% discontinued the drug over 4 years, with 11% moving to combination therapy (fibrates). Of those continuing, response...
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Prevalence of Serologically Defined Celiac Disease in Patients With IBS in Asia: A Multicountry Hospital‐Based Study - https://t.co/yotv0ga2Xm We (aiims_celiac) break the notion that CeD doesn’t exist in Asia. #celiac #AIIMS
onlinelibrary.wiley.com
Background and Aim Celiac disease (CeD) is not adequately recognized in Asia. We aimed to assess the prevalence of CeD in patients with irritable bowel syndrome (IBS) in six Asian countries and...
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Even worst experience with Cutiglow , ordered a topical hair treatment(tugain f) and got antifungals(that too physician samples). They don’t have anyway to contact them. Is there anyway to sue them???
@krishadoshii @culturecircle__ @riteshagar Had a similar experience with website called cutiglow ... There was an order from my family member and they didn't respond for 15 days , customer care is useless... Now I am avoiding these sites as much as possible
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Check out our new paper in JGH with long term outcomes of EUS-GE and Enteral stents showing improved survival in patients achieving clinical success, adding to the limited long-term data on this topic @DrLakhtakia @docdhir @DouglasAdlerMD @GVanell5 @JoanB_Gornals @Nareshbhat14
📢 Our study on palliation of malignant GOO is out now in Journal of Gastroenterology & Hepatology! 🔎 Compared #EUSGE vs Enteral Stents ✅ Higher clinical success with EUS-GE 💡 Clinical success = improved survival @drsridhars 👉 https://t.co/ghXlFizfxG
#Endoscopy #MedTwitter
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Animal models provide direct evidence that red meat consumption causes gut inflammation and dysbiosis. https://t.co/tAza1CPwPi
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New in the @TheLancet :Arguably the highest fibrosis improvement in #MASH trials to date #livertwitter @ebtapper @schattenbergJ @AlkhouriNaim @akerotx @scottisaacsmd @NoureddinNabil @ArunJSanyalVCU Safety and efficacy of once-weekly efruxifermin versus placebo in metabolic
thelancet.com
Efruxifermin resulted in greater improvements in fibrosis than placebo after 96 weeks, warranting further investigation in phase 3 trials.
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RCT on Simvastatin ➕carvedilol after 🩸 improves survival. Open label single 🏥 clear limitations; Findings similar to BLEPS trial but different to LIVER HOPE. Right combination and right subgroup may be🔑 #liverx @AmJGastro @BavenoCoop @ebtapper
https://t.co/P1LndZT0tx
journals.lww.com
en label randomized controlled trial with superiority design. Patients with cirrhosis (Child-Pugh score 5–12) were randomly assigned to receive either simvastatin (20 mg once-daily) (n = 130) or no...
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Official journal of the American College of Gastroenterology | ACG. A very relevant work from AIIMS exploring role of statins in cirrhosis. Great work @Sanchit30497977 @Sam_ogre
journals.lww.com
en label randomized controlled trial with superiority design. Patients with cirrhosis (Child-Pugh score 5–12) were randomly assigned to receive either simvastatin (20 mg once-daily) (n = 130) or no...
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A biocompatible Lossen rearrangement in Escherichia coli | Nature Chemistry Engineered Bacteria can convert plastics to paracetamol Novel discovery💥💥 @INASL_Liver @AASLDtweets @EASLedu @JasmohanBajaj @ebtapper
nature.com
Nature Chemistry - Biocompatible chemistry merges chemo-catalytic reactions with cellular metabolism for sustainable small-molecule synthesis. Now a biocompatible Lossen rearrangement has been...
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A lot of sweat from different parts of world, lot of AIIMS students collaborating culminating in this wonderful work. Kudos to our lead @ShubhamMehtaGI. Bottom line : 1 in 3 is non-adherent to GFD. #AIIMS_celiac
Happy to share that my abstract on “Prevalence of compliance to gluten-free diet in patients of celiac disease: a systematic review and meta-analysis” has been selected for oral presentation (Best 5 abstracts out of 119) at the 15th edition of Best of DDW-2025
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