ISACB
@AppliedCVB
Followers
492
Following
585
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International Society For Applied Cardiovascular Biology
Joined November 2012
Member publication alert:. Mitochondrial ROS drive foam cell formation via STAT5 signaling in atherosclerosis.
science.org
Mitochondrial ROS activate STAT5 to drive foam cell formation, inhibiting STAT5 alters macrophage metabolism and stress response.
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Member publication alert:. The Young Professionals Network: A New Initiative for The Heart Valve Society.
journals.sagepub.com
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Member publication alert:. Established and Emerging Roles of Epigenetic Regulation in Diabetic Cardiomyopathy.
onlinelibrary.wiley.com
An increasing number of individuals are at high risk of type 2 diabetes (T2DM) and its cardiovascular (CV) complications, which challenges healthcare systems with an increased risk of developing CV...
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Member publication alert:. The impact of chronic kidney disease on arteriovenous fistula remodelling: studies in a murine model of Autosomal Dominant Polycystic Kidney Disease.
journals.physiology.org
The arteriovenous fistula (AVF) is the gold standard for hemodialysis vascular access, although inadequate vascular remodelling and intimal hyperplasia pose a major limitation. It is essential to...
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Member publication alert:. Focal Adhesion Kinase Drives Rho/ROCK and mTOR Signaling to Protect and Augment Aortic Dissections.
jacc.org
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Member publication alert:. Temporal dynamics of angiogenesis: the emerging role of mechanoregulated pathways.
portlandpress.com
Controlling the formation of new blood vessels, i.e. angiogenesis, is a critical challenge for the success of regenerative medicine. The development of effective strategies is hindered by our...
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Member publication alert:. Volumetric 3D Printing and Melt-Electrowriting to Fabricate Implantable Reinforced Cardiac Tissue Patches.
advanced.onlinelibrary.wiley.com
This study presents an implantable reinforced cardiac patch (RCPatch) combining volumetrically 3D-printed metamaterials with melt-electrowritten (MEW) meshes. The design integrates tunable stiff...
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Member publication alert:. Sex differences in a murine model of infective endocarditis.
link.springer.com
Basic Research in Cardiology - Infective endocarditis (IE) is a highly lethal disease with a notable male predominance, yet the biological basis for this sex disparity remains unclear. We...
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Member publication alert:. Cross-linked poly(alkylene citrates) with L-glutathione for vascular tissue engineering: structure-property relationships and cell-type dependent response to oxidative stress.
pubs.rsc.org
Cross-linked poly(alkylene citates) (cPAC) based on 1,6-hexanediol (cPHC) and 1,8-octanediol (cPOC) and modified with 0.4, 0.8 and 1.6% w/w l-glutathione (GSH) were synthesized as potential materials...
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Member publication alert:. Phosphate Salt Selection Affects Mortality and Vascular Calcification in the Adenine-Induced CKD Mouse Model.
journals.physiology.org
Patients with chronic kidney disease (CKD) are at an increased risk for vascular calcification (VC), a strong predictor of cardiovascular events. Rodent models with elevated dietary levels of adenine...
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Member publication alert:. Differential regulation of the HIF-1α/apoptosis axis by miR-126-5p in cardiac cells during ischemia/reperfusion injury.
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Member publication alert:. Inhibition of tenascin C rescues abnormally reduced Na currents in dystrophin-deficient ventricular cardiomyocytes.
journals.physiology.org
Cardiac arrhythmias significantly contribute to mortality in Duchenne muscular dystrophy (DMD), a severe muscle disease caused by dystrophin deficiency. Using the mdx mouse model for human DMD, we...
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Member publication alert:. Indoxyl sulfate: fuelling cardiovascular inflammation and calcification.
academic.oup.com
This editorial refers to ‘The role of uremic toxin indoxyl sulfate in the pathophysiology of aortic valve stenosis’ by P. Düsing et al., https://doi.org/10
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Member publication alert:. The sodium/glucose cotransporter 2 inhibitor empagliflozin is a pharmacological chaperone of cardiac Nav1.5 channels.
journals.physiology.org
Diminished peak sodium current (INa) is a causative factor for slowed ventricular conduction and cardiac arrhythmias in patients with Duchenne muscular dystrophy (DMD), a devastating muscle disease...
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Member publication alert:. Short- and Long-Term Effects of Pulsed Ultrasound Cavitation Therapy of Calcified Valvular Interstitial Cells in Culture.
umbjournal.org
Calcific aortic valve disease (CAVD) resulting in aortic stenosis (AS) is the most common valvular heart disease, affecting 2%–7% of people over the age of 65 years [1–3]. CAVD is an active, cellul...
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Member publication alert:. Sexual Dimorphism of Plasma and Tissue Proteomes in Human Calcific Aortic Valve Stenosis Pathogenesis.
ahajournals.org
BACKGROUND: Calcific aortic valve stenosis is a global clinical burden, impacting around 2% of the population over 65 years of age. No pharmacotherapeutics exist, with surgical repair and transcath...
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Member publication alert:. A multi-omics strategy to understand PASC through the RECOVER cohorts: a paradigm for a systems biology approach to the study of chronic conditions.
frontiersin.org
Post-Acute Sequelae of SARS-CoV-2 infection (PASC or "Long COVID"), includes numerous chronic conditions associated with widespread morbidity and rising heal...
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Member publication alert:. Design of a Corrugated Vascular Graft with Enhanced Compliance and Kink Resistance.
onlinelibrary.wiley.com
The development of a small-diameter vascular graft for coronary artery bypass grafting necessitates a balance of key biomechanical properties to prevent failure. Adding a corrugated geometry to our...
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