Scientists identified Schlafen 11 as an 🧬 ssDNA-activated RNase, which was essential for the innate #immune responses induced by intracellular ssDNA and adeno-associated virus #infection. @SciImmunology | 👉 https://t.co/RQxmOq1PLP

Congratulations🥂to postdoctoral researcher Krist Antunes Fernandes @KristAntunes of the Lim lab! She's been named a 2024 Pew @pewtrusts Latin American Fellow in the Biomedical Sciences for her work toward understanding maternal-offspring immune crosstalk. https://t.co/7VSiqLI4mL

Microbial β-glucuronidases strike a balance. Specific gut #microbial β-glucuronidases influence endobiotic homeostasis (hormones and neurotransmitters) and are inhibited by diverse FDA-approved drugs https://t.co/pbhj0uAvFc

Online now: Microbiota dictate T cell clonal selection to augment graft-versus-host disease after stem cell transplantation

The #Schlafen11 protein, identified as sensor for single stranded DNA #ssDNA, may be part of new class of pattern recognition receptors. Read more: https://t.co/leB7WB0iG2

#PositiveResearchCulture is hard to define. We know it when we experience it, and we certainly feel it when it is absent. In #ImmunologyFutures @ImmunolCellBiol we ask: how can #universities and institutes nurture a positive culture? 1/13 https://t.co/aDXyD75hLY

What if there was an antibiotic that doesn't disrupt the gut microbiome? There is now. A discovery published @Nature today https://t.co/njtUddaJHo @PaulHergie and colleagues @UofIllinois @justsaysinmice

In science, all outcomes matter. But we all know how it goes with research journals: “No positive results? Sorry. We only publish highly impactful findings.” 📍 The new article in Nature describes this issue well: “Without sharing negative studies and data, researchers could

Dietary vitamin D modulates the gut #microbiome to enhance the response to #cancer immunotherapies, according to a recent Science study in mice. 📄: https://t.co/WJ9co9UfaP #SciencePerspective: https://t.co/XeCz7mzu4w

Opportunities and challenges for T cell-based influenza vaccines https://t.co/VjW0Ucaugi

The potential to use mRNA as a general therapeutic modality is limited by its instability and low translation capacity. A paper in @NatureBiotech reports on mRNA with engineered poly(A) tails, which produces prolonged higher levels of protein. 🔒

A common theory behind increased RSV cases numbers among children after the end of Covid lockdowns was “immunity debt”. In this fascinating analysis now in @CIDJournal, another explanation emerges--vastly increased testing, esp of older kids. @sabeti_lab https://t.co/OAagmtBDFT

Short-chain fatty acids: linking diet, the microbiome and immunity https://t.co/MX95n2Mgeq

In the latest issue! A versatile CRISPR-Cas13d platform for multiplexed transcriptomic regulation and metabolic engineering in primary human T cells

How knowing the gut microbiome constituents can promote success of immunotherapy for cancer https://t.co/oGUZr7v37o @NatureMedicine @LawleyLab

A single dose of a novel dengue #vaccine showed efficacy against disease. https://t.co/nQWmynqH7P #dengue #IDTwitter @NEJM

Why allergic asthma (AA) decreases the risk of COVID-19? A new study found the answer. It is the differential expression of conventional Dendritic Cell 2 (cDC2) between allergic asthma (AA)/COVID-19 and controls that’s responsible for this association. 1/

When you go out of the lab to interact with non scientists https://t.co/VBARcB0iu5

Researchers have created an easy-to-use, open-source #bioinformatics pipeline that can detect potential neoantigen targets for #immunotherapy that are shared across patients with cancers, including #melanoma. @nsalomonis @TTilburgs @CincyInformatix https://t.co/GqLXWtYdEj

Professora Ana Paula Duarte de Souza palestrante no The 31st Symposium on Intestinal Microbiota, em Tóquio