André Görgens
@andregorgens
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Researcher @karolinskainst, passionate about #exosomes/#extracellularvesicles #flowcytometry, #bioengineering, #therapeutics, #biomarkers, #stemcells.
Stockholm, Sweden
Joined October 2017
Excited to share our now-published @ISEV_JEV paper on Extracellular Vesicle storage conditions! Should be of interest to anyone who stores EV preps, or dilutes EVs, in PBS, even short-term. We identified suitable alternatives. Please share - thanks! 🧵1/7 https://t.co/tMEOlnEqxP
isevjournals.onlinelibrary.wiley.com
Extracellular vesicles (EVs) play a key role in many physiological and pathophysiological processes and hold great potential for therapeutic and diagnostic use. Despite significant advances within...
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I'm organizing the doctoral course 'Extracellular Vesicles: Progress Towards Diagnostics and Therapy' in Oct 2025 at @karolinskainst in Stockholm Open for all doctoral students & postdocs, also external ones! Thanks for sharing! Register here before May 6: https://t.co/qNU5CCFOWr
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New paper out💥 in @NanoLetters High throughput single particle profiler with simple confocal imaging. We used this new method to study protein-lipid interactions, drug membrane interactions and biophysics of nanoscale particles from human donors:
pubs.acs.org
Single particle profiling (SPP) is a unique methodology to study nanoscale bioparticles such as liposomes, lipid nanoparticles, extracellular vesicles, and lipoproteins in a single particle and high...
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In case you missed our recent webinar on utilizing antibody-binding Extracellular Vesicles for cancer targeting and as new EV reference material, here you go:
🚨 Webinar Recording Now Live! 🚨 "Leveraging Engineered Antibody-Displaying EVs for Targeted Drug Delivery and Advanced Research Applications" presented by Oscar Wiklander and André Görgens in now available on @Vesiculab's YouTube channel https://t.co/3vBus6e187
#exosomes #EVs
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Here's our ExoZoom schedule for Fall 2024 - looking forward to exciting sessions! Join today's call if you're interested in the announcement of the upcoming Swedish EV Network meeting in Stockholm - save the date: March 26-27, 2025 👀
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We continue development of our Single Particle Profiler and now we make it more accessible for users who do not have FCS modality on their microscopes. https://t.co/cVWUTsJp6w A thread🧵
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Big thanks to all co-authors: Sai Kiang Lim, @VaderPieter, @BGiebel, @AndaloussiLab, Vivian Nguyen, @Joadwe, Tobias Tertel, Andre Choo, @simon4189, Kyra Defourny, J. Padmanabhan, @EstherNolteHoen, Marianne Verhaar, Beklem Bostancioglu, @AntjeZickler, Jia Mei Hong, Jennifer Jones
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Happy to share this inter-laboratory study on MSC-EVs, led by @BasvanBal and me: We use a new Multiplex Bead-Based #ExtracellularVesicle #flowcytometry panel to compare MSC-EV surface protein marker signatures from 5 labs. Just published in @ISEV_Journals: https://t.co/CkRL9Peaw7
isevjournals.onlinelibrary.wiley.com
Mesenchymal stromal cells (MSCs) are promising regenerative therapeutics that primarily exert their effects through secreted extracellular vesicles (EVs). These EVs – being small and non-living –...
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Really happy to see this finally published! Also excited that these EVs will be made commercially available at @Vesiculab - enabling everyone to use Fc-EVs for their experiments and help qualifying them as a potential new type of Extracellular Vesicle reference material.
Engineered EVs displaying antibodies for targeted cancer therapy: Oscar Wiklander, Samir EL Andaloussi at @karolinskainst et al have published a very important article for the EV community https://t.co/dbm2VAC83a
@Vesiculab exclusively commercialises these Fc-EVs, as Vesi-Bind Fc
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Happy to share the new paper from our lab published in Nature Biomedical Engineering today. Congrats to @WiklanderOscar @AndaloussiLab & all other authors! We demonstrate the use of engineered Fc-binding Extracellular Vesicles for targeted cancer therapy: https://t.co/xxe1vAr57x
nature.com
Nature Biomedical Engineering - Extracellular vesicles decorated with an antibody-binding moiety specific for the fragment crystallizable domain can be used as a modular delivery system for...
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Online now: Targeting nucleic acid sensors in tumor cells to reprogram biogenesis and RNA cargo of extracellular vesicles for T cell-mediated cancer immunotherapy
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Excited to share our latest work from @AndaloussiLab @DanielHagey @karolinskainst, just published in @ScienceAdvances! We studied transcriptional responses of cells exposed to different EV doses from various cell sources: https://t.co/OVTPSuvjbe
#extracellularvesicles #exosomes
science.org
Extracellular vesicles are promising delivery vectors, but it is essential to consider their cell source and dose.
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Latest @biorxivpreprint preprint from @AndaloussiLab in collaboration with our group: Multimodal engineering of extracellular vesicles for efficient intracellular protein delivery https://t.co/EKihOpAX4k
@IdrmOxford
biorxiv.org
Extracellular vesicles (EVs) are promising tools to transfer macromolecular therapeutic molecules to recipient cells, however, efficient functional intracellular protein delivery by EVs remains...
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In today’s #ExoZoom, we’ll hear a talk from @andregorgens about EV characterization by Flow Cytometry #EVflowcytometry Title: Blood, Sweat and Tears: Analysis of EV Heterogeneity by Flow Cytometry More info about ExoZoom and The Swedish EV Network: https://t.co/F0Uu0FwXWP
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I'm organizing the doctoral course 'Extracellular Vesicles: Progress Towards Diagnostics and Therapy' in Oct 2023 at @karolinskainst in Stockholm with @DanielHagey @AndaloussiLab Open for all doctoral students & postdocs! Register here before May 15: https://t.co/H3YzpRple3
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In todays #ExoZoom we'll have the opportunity to listen to @Dr_NawazM presenting his recent paper in Advanced Science. Looking forward to hear about original work presented by the first author! Are you an EV researcher in Sweden, sign up at: https://t.co/uuHTyfXIC8
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🥳👏👏Up-to-date review from @DhanuGupta90, @karolinskainst, Prof. Matthew J.A. Wood @UniofOxford, and @AndaloussiLab on 'Biodistribution of therapeutic extracellular vesicles'! https://t.co/ji2GmbUZaJ
#EVs
#targeteddelivery
#CNS
#Exosomes
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Check out this EV course at @uniofgothenburg organized by @RossellaCrescit, with invited lectures by @janlotvall @CeciliaLasser @KarinEkstrom_ & more! Applications open for all PhD students until April 21 All info: https://t.co/0xBmjt5He9
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This afternoon we will be listening to Loes Teeuwen, @SusanneGab group, KI, presenting a @NaturePortfolio (Biomedical Engineering) paper: https://t.co/ff3XMmEaFp in #ExoZoom
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🎉New in #JEV🎉A compendium of single extracellular vesicle flow cytometry. A collaboration from @IsevOrg @ISAC_CYTO and @isth to improve robust and reproducible EV Flow cytometry research. A must read for researchers using #flowcytometry and #EVs 👉 https://t.co/Iemc6RpeCi
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