Xiang Li
@Xiang_Li1
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Experienced yeast breeder/ Previous PhD student @univgroningen @HeinemannLab /Postdoc researcher @chalmersuniv @prism_lt/ personal points of view only
Gothenburg, Sweden
Joined February 2016
Our work, led by former postdoc @Liulabscripps and Professor @jaykeasling, on the complete biosynthesis of QS-21 in engineered yeast is out now in @Nature. We report the sustainable supply chain of an essential adjuvant for global immunization here:
nature.com
Nature - QS-21—an FDA-approved vaccine adjuvant—and several structural analogues of QS-21 can be synthesized in engineered yeast strains, and this process is much less laborious...
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Impressive! Thrilling work by Dr. Tian, congrats!
Excited to share - EcORep! Now you can simply electroporate a PCR product into E. coli and let the linear DNA replicate orthogonally in the cell. EcORep can be used to evolve proteins rapidly and continuously!
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Please RT We have an open PhD position in our group to study how growth regulators interact with the cell cycle. If you are interested, check the job ad to apply: https://t.co/uoS7XkCkv3. For any questions, feel free to contact me. Deadline is October 2nd.
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Our group has an open PhD position on growth regulation and the cell cycle. If you enjoy exploring fundamental biological questions, come join our group @univgroningen @ResearchGbb. Further details & application link: https://t.co/JbtemEzjX1 Please RT.
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Are you looking for a highly detailed, robust and beginner-friendly CRISPR/Cas9 protocol for budding yeast? We have what you need! https://t.co/4e2A44AJA7 (plasmids on Addgene: https://t.co/GaT1Kkzg1T ) Great work from ex-postoc Daniele Novarina!
star-protocols.cell.com
STAR Protocols is an open access, peer-reviewed journal from Cell Press. We offer structured, transparent, accessible, and repeatable step-by-step experimental and computational protocols from all...
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Multi-omics analyses of the transition to the Crabtree effect in S. cerevisiae reveals a key role for the citric acid shuttle
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A software package for analysis of plate reader data (and some more insights into glucose transporter regulation) from @nandomgu et al. https://t.co/zgX25xhWFQ
journals.plos.org
Author summary Time series of growth and of gene expression via fluorescent reporters are rich ways to characterise the behaviours of cells. With plate readers, it is straightforward to measure 96...
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@ChoeMangyu and I wrote a perspective about the new generation of genetically encoded tools for measuring and manipulating metabolism. We hope this perspective will encourage more labs to start using these tools. 1/3
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Why so many transporters for the same nutrient? @nandomgu explores this question in PLOS Computational Biology https://t.co/WS1NLmHNwZ
journals.plos.org
Author summary From yeast to humans, cells often express multiple different types of transporters for the same nutrient, and it is puzzling why a single high-affinity transporter is not expressed...
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Do harmful mutations have a constructive role in evolution? 🤔 Our new paper in @NatureEcoEvo shows that various morphological features of the budding #yeast evolve as a by-product of harmful and subsequent compensatory mutations. https://t.co/uY4kkVSv6Y 1/9
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#OnThisDay 1879: Scientist Maud Menten was born. She co-devised the Michaelis-Menten equation, one of the fundamental models in enzyme kinetics #WomenInSTEM
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Happy birthday Arjen!
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China approves first self-developed COVID-19 vaccine https://t.co/y3ctMqRBjd - It shows 79.34% efficacy - It will be provided free of charge to all Chinese people - China will vaccinate senior citizens, people with underlying conditions & general public in an orderly manner
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Such an intuitive (and cool) way to represent the cell cycle by simply using your left hand🤟🏻
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A new virus, originating from Wuhan in China, is quickly spreading across the country and around the world. This video highlights the key things you need to know about the outbreak and how science can help control it. The latest: https://t.co/d0LDFrEXNA
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Online now! mTORC1 directly inhibits AMPK to promote cell proliferation under nutrient stress https://t.co/FMOTXIXKuT
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