Vishwaja Jhaveri
@Vishwajaj
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Doctoral student in Jean-Yves Roignant's group @unil working on RNA mods• Former group member @RaviMLab • Gene Expression Regulation • Epitranscriptomics
Mainz, Germany
Joined October 2019
My first preprint with the lab is out 🎉! We benchmarked the ability of our own basecalling models to detect RNA modifications using @nanopore direct RNA sequencing. Grab a coffee and check out the thread below 🧵! https://t.co/V8PJfHAtEP 1/10
biorxiv.org
In recent years, nanopore direct RNA sequencing (DRS) has established itself as a valuable tool for studying the epitranscriptome, due to its ability to detect multiple modifications within the same...
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It's not only that this "we're going to sequence our way into figuring out biology" stuff is harmful to science it's that any "we're going to figure out biology using this one approach" is harmful. Massively multidisciplinary research is the only way to figure out biology
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What a great line-up of topics covered! So glad I am a part of it. #EMBODrosophila @EMBLHeidelberg @EMBO
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Very sadly, not all PIs care about this or subscribe to this philosophy. Glad to have worked with one who does @RaviMLab
The point of grad school or a postdoc is not to learn a bunch of techniques or get some high impact factor papers (though that WILL help you get to the next stage). The point is learn how to think like a scientist: how to plan/design experiments, how to write, how to analyse data
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This is fake – I did *not* tweet out a link to The New York Times!
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💡This is the first study to link m6A modification to neuronal activity! It provides a foundation to understand how altered levels of m6A methylation can contribute to synaptic function. @Naveenkcg @NawalpuriBharti @R_Sarayu @Vishwajaj
@DBT_inStem @serbonline @iiscbangalore
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Looking for methods to measure #m6A? Happy to introduce Phospho-tag m6A assay, a highly efficient and accurate method for quantifying #m6A specifically from #mRNA...and all in one pot! Worry no more about your rRNA contamination! Congratulations @AashiqHMirza and collaborators!
Selective detection of m6A derived from mRNA using the Phospho-tag m6A assay https://t.co/oVJCeJnDRj
#bioRxiv
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Happy to share our latest work showing how m6A and YTHDF proteins contribute to the localization of select transcripts in neurons. Congratulations to our very talented postdoc Mathieu Flamand!
academic.oup.com
Abstract. The transport of mRNAs to distal subcellular compartments is an important component of spatial gene expression control in neurons. However, the m
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Here is another funding opportunity for researchers who had to flee from Ukraine. Funding for guest research stays 6-12 months.
Unterstützung für geflohene Forschende aus der #Ukraine: Die Stiftung unterstützt Wissenschaftler:innen dabei, ihre Tätigkeit vorübergehend in Deutschland fortzusetzen. Anträge können ab sofort eingereicht werden👇 https://t.co/lNdnZajxBh…
#ScienceForUkraine #StandWithUkraine
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Happy to share a recent review article that I and @deepak_iisc wrote together. Here we discuss the issue of spatial heterogeneity of protein expression in neurons and how ribosomes are modulated in a compartmentalized fashion to generate this variation. https://t.co/a7Jis2dA1Z
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Congratulations Dr. @NawalpuriBharti! Very happy to see this. You played a huge role in my formative years
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Jamie's manuscript is now on BioRxiv. Check it out! A single 2'-O-methylation of ribosomal RNA gates assembly of a functional ribosome
biorxiv.org
RNA modifications are widespread in biology, and particularly abundant in ribosomal RNA. However, the significance of these modifications is not well understood. We show that methylation of a single...
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We are looking for a postdoc and PhD students to join us in various projects @uni_mainz. If you’re interested in vision, neural circuits, and how they're robust to developmental and environmental perturbations, find more information here https://t.co/cRCT91mB0o. Please RT
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Asking students trivia questions when they present their data in a seminar is borderline bullying
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Cool study by @MeyerLabDuke monitoring m6A in single cells. Congratulations Meyer lab!
pubmed.ncbi.nlm.nih.gov
N6-methyladenosine (m6A) is an abundant RNA modification that plays critical roles in RNA regulation and cellular function. Global m6A profiling has revealed important aspects of m6A distribution and...
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100% agreed
For those of you interested in a nice overview on the m6A field, mentally swap "miRNA" with "m6A" in the abstract of this review 😀
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