Toby Johnson
@TobyJohnson144
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@Lindemanntrust Fellow @ajlinklab | DPhil @OxfordChemistry | MChem @DurhamChemistry | @HLAGroupOx @ChemLangton @mcgonigalgroup Hunter group @ajavestro alumni
Joined December 2021
Amazing to have this come online on the day of my viva - will hopefully be able to celebrate the success of both (fingers crossed) by the end of the day!! 😅 🤞 🥳
“Molecular Machines For The Control Of Transmembrane Transport” perspective out in @J_A_C_S Congratulations @TobyJohnson144
https://t.co/qTMzVIt7lm
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It's that time of year again - @cenmag Molecule of the Year! There are some fascinating molecules in there so vote for your favourite. We aren't biased of course, but there's a cool-looking cyclo[48]carbon catenane in there... https://t.co/0YxmOtRLXm
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We are seeking our third cohort of BioE Ph.D. students! Applications due by the end of the month for Fall 2026 admission. Learn more: https://t.co/pRxCNW0v0l
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#OnTheCover A High Modulus, Multi-Stimuli Responsive, Interwoven Protein Network With Topologically Confined Micro-Association (Wen-Bin Zhang and co-workers) https://t.co/qhGcU0q4vX • https://t.co/DIZp9Gy7TZ
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Uphill Anion Transporters with Ultrahigh Efficiency Based on N‐Heterocyclic Carbene Metal Complexes
onlinelibrary.wiley.com
Metal complexes with N-heterocyclic carbene (NHC) ligands enable highly efficient and selective anion transport across lipid bilayers, exhibiting remarkable activity with an EC50 as low as 3.6 pM....
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Had a great time hosting @DirkTrauner yesterday for his talk as part of the @omenndarlingbio seminar series 👨🏼🔬 incredible presentation with some eye watering applications of photoswitches for the restoration of human vision ⚡️
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Online now: Catenated cyclocarbon: Stabilizing cyclo[48]carbon in solution with mechanical bonds https://t.co/DWFYf2hdIc
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Come work with us! We have a PhD opportunity available with Hess and Giuliani groups. Please reach out if you are interested. @Jeannine__Hess @CRUKCOLcentre
https://t.co/MDiINAsBq5
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Excited to speak at Princeton Bioengineering this Thursday, October 9. https://t.co/OJuH53ajjE
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Our work on the unidirectional motion of a CD is now in the September issue of Chem and on the cover! Many thanks to the whole team and @Chem_CP for the highlight! @enxu_liu
https://t.co/cqxQeQF5yU
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A promiscuous #rSAM enzyme achieves diverse peptide cross links at non-canonical residue sites. @taikade (Eastman) @agr_chemistry (Roberts) @vahooster (Bandarian) @utahchemistry @uutah @pnasnews
pnas.org
Disulfide bonds stabilize many bioactive peptides, but their susceptibility to reduction under physiological conditions limits broad applicability ...
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Put a cyclocarbon in a vial! After more than a decade endeavour in the Harry’s group,@HLAGroupOx finally, we made it happen.
phys.org
In a new study led by Oxford University's Department of Chemistry, chemists have demonstrated the synthesis of a cyclocarbon that is stable enough for spectroscopic characterization in solution at...
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⭕ Synthesising a new carbon allotrope Amazing work from @HLAGroupOx, published this week in @ScienceMagazine: a cyclocarbon that is stable enough for spectroscopic characterisation in solution at room temperature. Read more: https://t.co/3GP8pyYXkD
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Another paper that was supposed to be quick, but ended up taking 4 years. Bringing high throughput screening and machine learning to the field of synthetic anion transporters... https://t.co/86dturMdXl
pubs.rsc.org
The development of synthetic compounds capable of transporting chloride anions across biological membranes has become an intensive research field in the last two decades. Progress is driven by the...
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Introducing the bionic azobenzene cell, AKA "Photocell", capable of modulating the viscosity of its internal membrane systems with light. I am still amazed how many photolipids cells can gobble up and accommodate. A wonderful collaboration with Howard Riezman, Suihan Feng,
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Anion transport across lipid bilayers by a hydrogen bonding homo[2]catenane
pubs.rsc.org
We report the first example of transmembrane anion transport mediated by a hydrogen-bonding homo[2]catenane. The catenane outperforms its non-interlocked analogues in chloride transport, highlighting...
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Super stoked to see our paper on ‘Coupling Synthetic Negative Feedback Loops’ out in @Chem_CP 🍌☺️🎉🐒 Shoutout to David for being my partner in crime throughout the whole project and for everyone else for their input. Make sure to have a read 📖
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@liampgriffin and I have reviewed recent advances in the heterometallic bonding chemistry of the alkaline earth metals @DaltonTrans. It was fun to put this together, and we hope it's useful! https://t.co/otbmwN8PQK
pubs.rsc.org
The alkaline earth metals are notorious for their tendency to form ionic compounds of their dications. In recent years, however, chemists have found ways to kinetically skirt around the edges of...
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🚨 | Myself and Prof. Glenn Hurst (@ChemistryatYork) are conducting a careers survey as part of an academic research project. 🔗 | Find out more and take the survey here: https://t.co/fuPuVKvCtr 🔁 | Reposts appreciated to spread the word.
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Our pipeline to compute thermal barriers of photoswitches💡 is out!🥳 We especially focused on NBDs for MOST🔋 and imines, but also stilbenes and DAEs. Try it out! You need just chemdraws and freeware to get libraries computed https://t.co/0Z0YB848ib
chemistry-europe.onlinelibrary.wiley.com
A semi-automated pipeline for the transition state search of molecular switches (PiTS3) is reported, which facilitates the search, optimization, and conformational analysis of transition states of...
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