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Thore Graepel Profile
Thore Graepel

@ThoreG

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AI & ML @Altos_Labs. Prev: @DeepMind & @MSFTResearch. #AlphaGo & #TrueSkill, family man, #GameOfGo, classical music (piano), meditation, Patterns of Thought

Cambridge & London, UK
Joined July 2009
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@ThoreG
Thore Graepel
5 months
What if you could think more clearly, solve problems more effectively, and see the hidden structures behind everything?.Welcome to Patterns of Thought—a journey into the fundamental concepts that shape our understanding of the world. 🧵👇.#MentalModels #FirstPrinciples
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@ThoreG
Thore Graepel
2 days
@statto A new perspective on aging and rejuventation - could be of interest to you!.
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@ThoreG
Thore Graepel
3 days
RT @TimePieChina: Can aging cells find their way back to youth?🤔. Scientists of @altos_labs propose a new phenomenological model, Cell Anne….
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@ThoreG
Thore Graepel
5 days
RT @Dr_Singularity: Anti Aging News. Escaping ageing through Cell Annealing. Researchers have introduced a new model called "Cell Annealing….
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@ThoreG
Thore Graepel
5 days
What if the blueprint for youth is never truly lost, just inaccessible?.Today, we're excited to announce the publication of our "Cell Annealing" model in which cells can be rebooted to restore their optimal, youthful state and escape ageing.
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www.nature.com
Cell Research - Escaping ageing through Cell Annealing—a phenomenological model
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@ThoreG
Thore Graepel
25 days
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@ThoreG
Thore Graepel
1 month
RT @Siharyvani: The "why won't this freaking.drawer open" starter pack
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@ThoreG
Thore Graepel
3 months
Let us appreciate the power of trade to create value. We all win when we exchange what we have for what we need, without barriers. Magic, indeed. Learn more: For more First Principles Thinking:
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@ThoreG
Thore Graepel
3 months
The magic of trade can have a dark side. Monopolies and monopsonies allow powerful actors to exploit weaker ones, manipulating prices and creating dependencies. When trade becomes unbalanced, those at the bottom face difficulty escaping exploitation.
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@ThoreG
Thore Graepel
3 months
How do we stop people from exploiting others? Meet the magic of competition. In a market full of alternative buyers and sellers, fair prices emerge and we can keep in check exploitative pricing.
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@ThoreG
Thore Graepel
3 months
Advanced magic: specialisation. When Alice and Bob have different opportunity costs for rice and fish they can specialise in producing the good for which they have comparative advantage - and obtain the other good(s) by trading. If you have a job, you probably do that every day!
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@ThoreG
Thore Graepel
3 months
Imagine Alice and Bob—one holds rice, the other holds fish. Alice prefers fish; Bob prefers rice. By trading, both improve their situations without needing to produce anything new. The magic of voluntary exchange makes the world a better place.
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@ThoreG
Thore Graepel
3 months
The magic of trade does not involve wizardry but operates as a powerful economic principle. The combination of diverse preferences, varying opportunity costs, and competition creates and distributes value from thin air.
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@ThoreG
Thore Graepel
3 months
Free trade feels a bit like magic because it can create something out of nothing. We access all sorts of goods and services, from haircuts to iPhones, even though most of us work in specialised jobs. Trump’s tariffs threaten to destroy that magic and undermine the invisible hand
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@ThoreG
Thore Graepel
3 months
RT @VividVoid_: gm
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@ThoreG
Thore Graepel
4 months
This substack post dives into:.- When absence counts as evidence.- Why logic sometimes fails.- How probability saves the day. Read it here and update your priors:. 👉
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@ThoreG
Thore Graepel
4 months
Bayes’ Theorem = math’s way of saying:. “If you keep seeing black ravens and no weird ones, maybe all ravens really do look black.”.Same with aliens: if we should have seen signs by now, the silence starts to matter. #BayesTheorem
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@ThoreG
Thore Graepel
4 months
Logic says:. “All ravens look black” → “This raven looks black.”. But seeing a black raven tells us nothing about all ravens. Probability, though? It lets us adjust our belief. One raven at a time.
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@ThoreG
Thore Graepel
4 months
Take the #FermiParadox. Vast universe. Billions of stars. Plenty of time. Still no alien signals. Should we lower our expectations?. Probability says. maybe yes.
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@ThoreG
Thore Graepel
4 months
I sometimes drop the line:.“Absence of evidence does not count as evidence of absence.”. Especially when someone says “It doesn’t exist — I looked.”.Feels clever. But guess what? Sometimes that absence actually does tell us something.
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@ThoreG
Thore Graepel
4 months
🚨 New #substack post: “Absence of evidence does not count as evidence of absence”. or does it?. Aliens, ravens, Sherlock Holmes, and Bayesian math collide. Come for the logic, stay for the probability. 👇🧵
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