TheBraunLab
@TheBraunLab
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We work on silent chromatin and epigenetic mechanisms using the powerful fission yeast model. Visit us at https://t.co/cEIMhPKgLx
Giessen, Germany
Joined August 2018
Deeply honoured to receive this year's Gateff Prize by the German Genetics Society @GfGenetik 🎓🧬 Recognition for an incredible team I had the privilege to work with during my PhD. @tcgcambridge @CamVetSchool @sangerinstitute @emblebi @ResearchMenzies
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This will be one of our last tweets on X. We’re leaving and have moved to @thebraunlab.bsky.social. Follow us there for updates on our research and collaborations! 🌟
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A previous recap of the findings can also be found here:
We are excited to share our latest preprint on #heterochromatin regulation: A systematic quantitative approach comprehensively defines domain-specific functional pathways linked to Schizosaccharomyces pombe heterochromatin regulation https://t.co/ak3lFGedRe
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Also, we’d like to thank all our collaborators and team members—@balazs_papp_lab, @ASadylab, @SarahLa47195747—and present/former BraunLab members, including @abubaka11715045 and @SarkadiZsuzsa, for their fantastic contributions. 👏
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Thrilled to announce that an advanced version of our study is now published in @NAR_Open! 🚀 Huge thanks to the reviewers for insightful comments and @SarahLa47195747 for invaluable contributions during the revision process. 🙌 Read more here:
academic.oup.com
Abstract. Heterochromatin plays a critical role in regulating gene expression and maintaining genome integrity. While structural and enzymatic components h
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This will be one of our last tweets on X. We’re leaving and have moved to @thebraunlab.bsky.social. Follow us there for updates on our research and collaborations! 🌟
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Also, we’d like to thank all our collaborators and team members—@balazs_papp_lab, @ASadylab, @SarahLa47195747—and present/former BraunLab members, including @abubaka11715045 and @SarkadiZsuzsa, for their fantastic contributions. 👏 @FB08_JLU @LMU_Muenchen @jlugiessen
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Thrilled to announce that an advanced version of our study is now published in @NAR_Open! 🚀 Huge thanks to the reviewers for insightful comments and @SarahLa47195747 for invaluable contributions during the revision process. 🙌 [Read more here: https://t.co/aM375Ls4NF]
academic.oup.com
Abstract. Heterochromatin plays a critical role in regulating gene expression and maintaining genome integrity. While structural and enzymatic components h
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My co-first author paper now out in @Nature SWR1 specifically exchanges H2A/H2B dimers for Htz1/H2B dimers in nucleosomes. Here we show double dimer exchange can be processive, explaining how SWR1 ‘proofreads’ dimer identity in a nucleosome. https://t.co/giVaXL7YLl
nature.com
Nature - Nucleosome flipping mediates a proofreading and processive mechanism of histone exchange driven by the chromatin remodeller SWR1.
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Excited to share our study on ZNF512B's role in binding NuRD, acting as a repressor, and facilitating DNA aggregation is now published in @NAR_Open! Big thanks to our amazing collaborators @OlallaLab, @JoelPMackay, Marek Bartkuhn, & Falk Butter! https://t.co/xCR08iKkrc
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Our PhD program is now open to applications for 2025 admissions. Too much cool science to summarize, take a look and apply! Deadline Jan 7th.
Call open: We are looking for motivated #PhD students who want to work at the interface between molecular life sciences and computational sciences. #IMPRS #IMPRSBAC @maxplanckpress @FU_Berlin @DRS_FU Check out our projects and apply until Jan 7th, 2025! https://t.co/rXXNAjk14M
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#JobOffer 🔎 Exciting opportunity to join the new #MSCA-DN #NUCLEAR 🧬 led by @MarcusBuschbeck as Project Manager! If you have a background in Life Science and EU Project Management, apply now 👇 https://t.co/GkwriNC6CC
@MSCActions #ProjectManager
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What's the most feared part of giving a talk? Answering questions.. Yet, this is the best place to clarify your ideas & create an atmosphere where the audience gets to a higher level of understanding & satisfaction. Here's the effective method I learned from @UriAlonWeizmann!
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Now out in @embojournal: FMI researchers in the @MarcBhler4 lab discovered that yeast communicate through secreted molecules to switch to less favorable nutrients when food is scarce, using mitochondrial proteins to decide the best menu 🍔
fmi.ch
To grow and survive, tiny organisms such as yeast must sometimes adapt their nutrient sources in response to changes in the environment. FMI researchers have now found that yeast cells communicate...
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Thanks to everyone joining our symposium “Quiescence from a Chromatin and RNA perspective” at @jlugiessen — especially our guest and local speakers! Many fruitful discussions and exciting keynote by @keisuke_goda! Looking forward to establishing a new training network @FB08_JLU
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New Study Alert! A comprehensive Schizosaccharomyces pombe atlas of physical transcription factor interactions with proteins and chromatin https://t.co/fPBJXYwOIj
#biorxiv_molbio
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Feierliche Amtseinführung der #JLU-Präsidentin Prof. Katharina Lorenz und Übergabe der Ämter der JLU-Vizepräsidenten für Studium und Lehre sowie für Wissenschaftliche Infrastruktur mit Staatsminister @Timon_Gremmels
https://t.co/YieHbPIrn2
@HMWK_Hessen
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The Journal Club by @NatRevMCB is a nice format to revisit papers having an impact on the field. Thanks for the opportunity to write about the study by Jih et al. on distinct roles of H3K9me2/me3 describing how #heterochromatin can be transcribed while still being silenced.
Now Online Heterochromatin as a balancing act between transcription and gene silencing https://t.co/Ecn1EpAUxx
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We identified a complex network of proteins that regulate MMEJ:NHEJ repair pathway balance in a chromatin context-dependent manner. With impact on cancer genomes. Paper is finally out:
nature.com
Nature Communications - DNA double-strand breaks are repaired by multiple pathways. The balance of these pathways depends on the local chromatin context, but the underlying mechanisms are poorly...
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Welcome Edith! Exciting start of a new era for the Crick!
We are delighted to announce that Professor Edith Heard has been appointed as our new director and chief executive! Edith, who is currently director-general at @EMBL, will succeed Paul Nurse in leading the Crick from the summer of 2025. 🔗 https://t.co/CcJR4TFxbF
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