Thomas Böttcher
@TBoettcher_Lab
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Professor of Microbial Biochemistry at University of Vienna. Investigating microbial metabolites and modulating bacterial behavior. #ChemicalBiology 🇺🇦
Vienna 🇦🇹
Joined June 2019
There will be a highly attractive doctoral school program shared with 9 other PIs from the pharmaceutical science department of University of Vienna. #DrugDevelopment #antibioticresistantinfections
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Please only apply online via the weblink. Skills in organic chemistry, NMR, natural product chemistry, chemical biology and biochemistry are desired, expertise in microbiology is a plus but alone not sufficient. @cemess_vienna
#PhD #ChemicalBiology
@Chemjobber
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We are looking for an excellent and highly motivated student in Chemical Biology for a PhD position in our group within the AIDD docfunds program @stem_univie to investigate anti-infectives from antagonistic microbial interactions. Apply until 03.05.2025: https://t.co/cEd9B5RzZf
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Our paper is now out in ACS Chem Biol! Here we discovered a new quinolone producer-Chitinivorax tropicus. I’m also very excited that our artwork was selected for the cover. I had a lot of fun creating it :) Huge thanks to our collaborators! @stem_univie
https://t.co/SVu3bq56Gd
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Potential for selective killing of bacterial pathogens such as multidrug-resistant N. gonorrrhoeae through activation of endogenous toxins @TBoettcher_Lab @NatureMicrobiol
https://t.co/A1W5o3RElY
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Check out our new research, fresh from the press: https://t.co/v90zGVKfbN
#chemistry
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If you're interested in #ChemicalBiology novel #Antibiotics or the #Chemistry of Microbial Interactions, you are welcome to follow our research on Bluesky
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A wonderful collaboration work led by @microbetracker with @MichiWagner4 @DOME_Vienna @JMF_Vienna @kirk3gaard @sotonbiosci with David Szamosvari from our lab on a Parkinson's drug affecting our gut microbiome is now published in @NatureMicrobiol
OUT NOW 💊Entacapone, a Parkinson's disease medication, sequesters iron resulting in a selective inhibition of gut microbial metabolism @MichiWagner4 @microbetracker @DOME_Vienna @JMF_Vienna @kirk3gaard @sotonbiosci
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Our study on drug-gut microbiome interactions is out! 🦠💊 @NatureMicrobiol We show that the #Parkinson's drug entacapone induces iron deficiency in microbes, leading to selective inhibition of microbial activity. Check the full story here:
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Check out our newest collaboration paper of our team members Verena and Viktoriia with the lab of David DeShazer (@OUSAMRIID) on the importance of 2-alkylquinolones for the virulence and competition of Burkholderia pseudomallei @univienna @cemess_vienna
https://t.co/lwDHcD7yPT
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Congratulation to our alumna Sina and our collaboration partners from the Hartig and Peter Labs @UniKonstanz on our joint paper on cooperative binding of guanidines into the guanidine-II riboswitch in NAR Genomics and Bioinform. @univienna @cemess_vienna
https://t.co/z9i2I4GSA8
academic.oup.com
Abstract. Riboswitches are involved in regulating the gene expression in bacteria. They are located within the untranslated regions of bacterial messenger
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A paper in a high impact journal then vs. now.
The academic job market in the good ol' days vs the academic job market today.
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Congratulations to Viktoriia @Viktoriia_Sav and our coworkers from the Fetzner lab for our recent paper in @CellRepPhysSci uncovering the last major mysteries of quinolone biosynthesis in Burkholderia. @univienna @cemess_vienna
https://t.co/pBGNAlYqoe
cell.com
Bacterial 2-alkyl-4-quinolones act as signals and antibiotics in various ecological niches. In contrast to other quinolone producers, Burkholderia thailandensis predominantly produces 3-methylated...
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Politics is just like microbial ecology: if you leave a niche unoccupied, some other potential pathogenic species will fill in. If you don't address problems and fears of voters within the democratic spectrum potential undemocratic parties will fill in the void and get voted.
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I much applaude the @ERC_Research for the new "lump sum" model, which in my opinion is the right move away from burreaucracy and I hope other research organizations will follow their example. Science needs freedom and trust and not restrictive nit-picky burreaucratic control.
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Seeking a PhD between Chemistry and Biology? There is an interesting opportunity for future PhD students in the direction bioactive small molecules in a highly interdisciplinary collaboration with the Gruene and Pjevac groups @univienna with our lab: https://t.co/XkqRW7cZnY
jobs.univie.ac.at
University Assistant Praedoc
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The Vienna Doctoral School in #Chemistry (DoSChem) of @univienna offers 17 fully funded #PhD positions, the call is open now until 14 April. Spread the word and apply here: ⤵ https://t.co/HN8qduhLZn (c) 📷 DoSChem #univie
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How the oxford comma matters in science: I have been invited to publish our next work in Nature Cell and Science 🤪🙄🤡 I have been invited to publish our next work in Nature, Cell, and Science 🤩🏆😍
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My personal opinion: better having high precision techniques than relying on mutation breeding (counts as non GMO) to obtain the same results just slower and with entirely unknown effects on the rest of the genome. So @Europarl_EN say yes to #NGTs.
We call on @Europarl_EN to next week vote in favour of #NGTs. This would mean EU farmers have access to better crops. ✅ Higher yields ✅ More climate resilient ✅ More resilient to pests and disease ✅ Require fewer inputs A win for food security & our environment.
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A nice article with video by @univienna 🇦🇹 about our research in microbial biochemistry 🦠⚗️🧪with some personal touch👨🏻🔬: https://t.co/XN7R96IBYQ
rudolphina.univie.ac.at
From the flu to the coronavirus – recent years have shown that infectious diseases are a tremendous problem. In the video, biochemist Thomas Böttcher explains the role that new biologically active...
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