Lena Skrutl
@Skrutlnize
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PhD student 'connecting the dots' @FlyJagannathan Lab. 'Squashing brains, collecting virgins & washing testes' are phrases I regularly use #Drosophila #Meiosis
ETH Zürich, Switzerland
Joined November 2019
Thrilled to share our paper is out in @PLOSBiology! 🎉 We explore how satDNA organization is linked to transposon repression. A huge thanks to my amazing co-first author @flyhi_ankita and all the collaborators who made this possible! 💕 Check it out here
journals.plos.org
Pericentromeric heterochromatin clusters into nuclear foci known as chromocenters, the proteome of which remains largely unknown. This study uses quantitative mass spectrometry to characterize the...
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Thrilled to share that our preprint on the role of satellite DNA in homologous chromosome pairing is out 🎉 https://t.co/BW6L1wS1TM I’m deeply grateful to my incredible co-authors, @FlyJagannathan & everyone who provided suggestions and support 💕 https://t.co/PwPlRxGb8d
researchsquare.com
During meiosis, chromosomes must find, pair and synapse with their homologous partner in the crowded milieu of the nucleus, without being entangled by non-homologous chromosomes1. Generally, homology...
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1 month left of the Phd, nothing is working, and thesis isn't finished yet..... its fine
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Excited to share our work in collaboration with the @ericjoycelab and @RanganLab highlighting the role of Stonewall in chromatin organization in Drosophila female germline, now published and featured on the cover @GenesDev. https://t.co/BYC40LFTD9
https://t.co/9wQnAUSZxr
NEW ISSUE ALERT!!! Check out the new Research, Outlook and Review Articles online now at Genes & Development. Click on the link for more: ➡️ https://t.co/9vDOzTkyaP
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A new study from @LabSantoro shows how nucleolus attracts genomics domains and establishes repressive chromatin marks. Special thanks to the contributors! Go now and check it out -
biorxiv.org
Repressive chromatin domains are often located at the nuclear lamina (NL) or nucleolus. Although nucleolar associated domains (NADs) have been recently mapped, the mechanisms of NAD association with...
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A green alga cell can swim 100 microns per second. Scientists put little baskets on a wheel. As algae became trapped, they pushed and spun the wheel around.
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Extremely jazzed to be awarded an @snsf_ch Ambizione grant! I'll be joining @DmmdUzh as a junior group leader where I'll be studying the intersection between cell size, senescence, and genome maintenance. Big thanks to @altmeyerlab 1/2
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A 392 year old Greenland Shark in the Arctic Ocean, wandering the ocean since 1627.
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pretty wild: a woman with amygdala damage was ~literally fearless, so doctors are like "hm what if we make you breathe a lot of CO2, probably won't bother you" but whoops "this was the first time patient SM experienced fear in any setting...since childhood"
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the synaptonemal complex of a single chromosome looks a lot like a snake moving around inside the meiotic nucleus!
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Wishing all the fly-pushers out there a wonderful #DrosophilaDay/#FlyDay as we celebrate the anniversary (11/18) of the isolation of the #Drosophila white-eyed mutant line w1118! #DrosLife #SciArt #FruitFlyArt
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Are you curious about the proteins orchestrating nuclear architecture? Whether and how chromatin organization affects gene expression and cell fate? Check out our preprint showcasing recent work in collaboration with the @ericjoycelab and @RanganLab.
biorxiv.org
The association of genomic loci to the nuclear periphery is proposed to facilitate cell-type specific gene repression and influence cell fate decisions. However, the interplay between gene position...
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Barcodes are everywhere, but what about in biology? In our new preprint we propose that somatic homolog pairing could be mediated by non-specific interaction "buttons" arranged in a barcode pattern 🧵 https://t.co/0w9HJk7aVv
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Jagannathan Lab news - Part 1 A new paper from the lab jointly led by super students @flyhi_ankita and @Skrutlnize. https://t.co/8CTNhovavU We performed a multi-tissue proteomic screen using our favourite satellite DNA-binding proteins, D1 and Prod, as baits. (1/6)
biorxiv.org
The pericentromeric heterochromatin of eukaryotic chromosomes primarily consists of abundant non-coding repeats known as satellite DNA, which promote accurate chromosome segregation and genome...
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