RogerMulet
@RogerMulet
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NL-based bioinformatician. Interested in epigenetics, leukemia and science in general. I support evidence-based practices.
Joined July 2021
Read our Spotlight article: One for All and All for One: New Insights into Enhancers Driving MYC Dysregulation https://t.co/TzdE76UB6S Its a commentary on the very nice paper by Iyer and colleagues!
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Second preprint now on biorxiv!! 🧵⬇️ thanks to all our co authors @MarijeHavermans @RogerMulet @SmeenkLeonie and others i cant find on here ! Also on bluesky 🦋: https://t.co/5zBEGIGlgj
@erasmusmcblood
Excited to share our preprint (@D_Pastoors): "MECOM is a master repressor of myeloid differentiation through dose control of CEBPA in acute myeloid leukemia"! https://t.co/XX6RqEC1fa MECOM is a TF whose overexpression leads to aggressive AML and with an immature phenotype. [1/15]
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EHA Research Conference in Malaga In March 2025: "Transcriptional control and chromatin alterations in normal and malignant hematopoiesis" Fantastic opportunity for junior investigators to present and discuss their work with young and experienced scientists. Great program!
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Congratulations to this year’s CBTH Scholars! Throughout the program, scholars explored a range of topics and were guided by mentors to elevate their projects to new heights. In addition to advancing their own research, they delved deeper into these key areas: 👉 Bayesian
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07 October 2024 at 16.00 CET Erasmus Hematology Virtual Lecture. We have: Kellie Machlus, Boston Children’s , with "Unraveling roles for megakaryocytes beyond platelet production through novel model systems" Spread the news! https://t.co/ICOMFc5jv5
@theclotthickens
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Don't miss it! Erasmus Hematology Virtual lecture 23 September at 16.00 CET with: Alexander Bick, Vander Bilt University, Nashville. Title: "Clonal hematopoiesis: causes, consequences and management" Link: https://t.co/ICOMFc5jv5
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Erasmus Virtual Hematology Lectures starts again on Monday September 2 at 16.00 CET! We have MAXIM PIMKIN from Harvard/Boston with: "Gene-regulatory networks in leukemia maintenance and immune escape". Link: https://t.co/ICOMFc5jv5 Spread the news! @pimkin
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New paper in Cell Reports: STAG2 mutations reshape the cohesin-structured spatial chromatin architecture to drive gene regulation in acute myeloid leukemia https://t.co/FrnzR3oGkk Another Regensburg/Rotterdam collaboration! @ClaudiaGebhard
@RogerMulet Fischer/Rehli
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Proud of the review by Roger Mulet-Lazaro on "Oncogenic Enhancers in Leukemia" in Blood Cancer Discovery in August issue. Great stuff for teaching! https://t.co/eBLKUwA1hr
@RogerMulet @BCD_AACR
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The Erasmus Hematology Virtual Lecture Series starts again September 2, with a fantastic line up: @pimkin,@AlexBickMDPhD, @theclotthickens, @jonasschluter, @job_dekker, @NBahlis, @Elsa2Bernard Retweet and share with your colleagues and friends https://t.co/ICOMFc5jv5
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New paper in NatureComm: "Epigenetic alterations affecting hematopoietic regulatory networks as drivers of mixed myeloid/lymphoid leukemia". https://t.co/soC6QFRLpZ Great Rotterdam/Regensburg collaboration: @RogerMulet @ClaudiaGebhard Bas Wouters @DelwelRuud Michael Rehli
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Extremely grateful for receiving the EHA advanced research grant! Looking forward delving deeper into the disease mechanisms underlying AML. Congratulations to all EHA award winners! #EHA2024 @EHA_Hematology @ErasmusMC @erasmusmcblood
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Excellent meeting alert! Join us in Rotterdam!
June 10/11: PhDs and postdocs will present their work at the "7th Molecular Hematopoiesis Workshop" in Rotterdam. Special guests: Ari Melnick, Iannis Aifantis, Els Mansell, Irene Roberts, George Vassiliou, Jamie O'Sullivan, Charles Mullighan. Join? Go to
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A big thank you to everyone involved in this week's joint @EBItraining and @EHA_Hematology computational biology training in hematology (CBTH) course. 2025 applications are now open if you want to be in the next cohort of early-career researchers: https://t.co/WM6juTqJBa
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The previous tweet was my first ever. 🤓🕺 We had another nice study in Blood, published in July. Allele-specific expression of GATA2 due to epigenetic dysregulation in CEBPA double-mutant AML | Blood | American Society of Hematology
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We generated t(3;8) MYC super-enhancer/EVI1-eGFP translocations in human cells. The importance of CTCF-facilitated loops in enhancer hijacking is demonstrated. https://t.co/lpdD3OUEPb
nature.com
Nature Communications - Chromosome rearrangements can be a cause of altered oncogene expression in cancer, such as a 3q26 translocation in some acute myeloid leukemias (AML) that leads to...
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Truly becoming the epidemic of the unvaccinated. So sad that so many people have been fooled by shamans and snake oil salesman
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