Robert J. Huebner
@RobertJHuebner1
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Joined June 2021
Stoked for the newest paper from @RobertJHuebner1 just out @MBoCjournal, where he's drilled deeper into his finding of PCP control of cadherin clustering! https://t.co/gyrkjJo9Zt
molbiolcell.org
Animals are shaped through the movement of large cellular collectives. Such morphogenetic processes require cadherin-based cell adhesion to maintain tissue cohesion and planar cell polarity to...
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I can't wait to start @CUDevBio @CUAnschutz ๐ feeling incredibly honored to join this amazing group of people and start my lab at the same time as @jen_mckey!!!
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#sciencetwitter are you interested in how cell clusters transit from non-to-migratory states in #embryos? Check out to our article in @NatureMaterials
@espina_hidalgo @naseermk @CristianMarcha9
#devbio #CellMigration #CellBio #mechanobiology #AFM
https://t.co/40mrCmwa68
nature.com
Nature Materials - Collective cell migration in embryonic tissues is triggered by cell softening due to a microtubule deacetylation pathway involving the mechanosensitive ion channel Piezo1.
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๐ต๐๐ ๐๐๐๐๐ ๐๐๐๐๐ We wondered how variations in cell-cell contact due to changes in intercellular adhesion strength impact cell growth and division in expanding dense 3D cell collectives - https://t.co/V2aItLEJKw
@CellPressNews Pressure on cells is visualized [1/5]
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...and we're on COVER @Dev_Cell! So stoked for @RobertJHuebner1 and @ShinuoWeng for their great work on this paper. https://t.co/ojkWjEOCcP
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Featured article: Hueber and Weng et al., Developmental Cell, ARVCF catenin controls force production during vertebrate convergent extension. https://t.co/jyOAafQRNy
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HUGE day for @RobertJHuebner1 and @ShinuoWeng and the whole Wallingford lab as their companion papers drop today in @Dev_Cell and @CellReports! I'll tweet out separate threads for each in a bit, but for now, I'll just let two awesome papers speak for themselves.
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We are very excited to share our preprint: Mechanics of cell integration in vivo โ๏ธ๐ธ๐ฌ๐งฎ. Wonderful collaboration with @DoostmohammadiL and @AboutalebAmiri ๐งฎ. https://t.co/nKwEiCyvZ8, So, how do cells navigate through complex 3D environments? ๐งต1/14โฌ๏ธ
biorxiv.org
During embryonic development, regeneration and homeostasis, cells have to physically integrate into their target tissues, where they ultimately execute their function. Despite a significant body of...
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This work led @RobertJHuebner1 to re-explore the poorly defined catenin, Arvcf. Remarkably, he and @ShinuoWeng found that Arvcf is not required for cell intercalation per se, but is required for robust force generation by the converging/extending tissue: https://t.co/V3BxAZS5p3
biorxiv.org
Axis extension is a fundamental biological process that shapes multicellular organisms. The design of an animalโs body plan is encoded in the genome and execution of this program is a multiscale...
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After 20 years focused on PCP & actomyosin in convergent extension, I'm thrilled for our new thrust to understand cell adhesion in this process. Two great papers from a massive co-lab between two fantastic postdocs, @RobertJHuebner1 and @ShinuoWeng are up now on @biorxivpreprint.
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Hello, I am a postdoc in John Wallingford's @jbwallingford lab at UT Austin.
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