PPNNottingham
@PPNNottingham
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Hello!π©βππ¨βπ This is Pharmacology, Physiology & Neuroscience at the University of Nottingham; a Research Division of the School of Life Sciences.
Nottingham, England
Joined September 2017
Amazing postdoc opportunity to work with Isabella Maiellaro at @UoNLifeSci @COMPARE_UoBUoN - please share!
jobs.nottingham.ac.uk
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Submit your papers to BJP! β¬οΈ World leading #pharmacology journal π₯ Community owned β‘ Fast high-quality peer review π¬ Transparency & scientific rigour π Option to publish #OpenAccess Find out more: https://t.co/PrZPowofOM Call for papers: https://t.co/62XQHxkpL4
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There's a new Guide to Pharmacology database release out now (2023.2). Details are on our release blogΒ https://t.co/Qz2SUEUTKd. Now over 12,000 ligands in total and 14 new target curated in this release.Β https://t.co/td0kWoM3vz
blog.guidetopharmacology.org
The latest release of the IUPHAR/BPS Guide to Pharmacology database was made on 7th August 2023. This database release is version 2023.2, and is the second release this year. The following blog posβ¦
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Read about the latest advances in malaria pharmacology, as well as the new @IUPHAR / @MedsforMalaria Guide to MALARIA PHARMACOLOGY - a web resource providing open and optimised access to data on the subject: https://t.co/WiS3n4vIsQ
#Antimalarial #Malaria #MalariaPharmacology
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"Use of NanoBiT and NanoBRET to characterise interleukin-23 receptor dimer formation in living cells" From @Dr_LauraK @SteveH025 and colleagues https://t.co/kQUoxk1ojH
pubmed.ncbi.nlm.nih.gov
These results indicate that receptor complexes form prior to ligand binding and are not sufficient to induce signalling alone. Our findings indicate that IL-23 induces a conformational change in...
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"Fluorescently tagged nanobodies and NanoBRET to study ligand-binding and agonist-induced conformational changes of full-length EGFR expressed in living cells" From @SteveH025 @Dr_LauraK and colleagues https://t.co/PHjrO1aNXN
pubmed.ncbi.nlm.nih.gov
EGFR targeting nanobodies are powerful tools for studying the role of the EGFR in health and disease and allow real time quantification of ligand binding and distinct ligand induced conformational...
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"Kinetic analysis of endogenous Ξ²2-adrenoceptor-mediated cAMP GloSensorβ’ responses in HEK293 cells" From Sean Cullum, @DVeprintsev and @SteveH025
https://t.co/BjIBhM3Z0I
pubmed.ncbi.nlm.nih.gov
Kinetic analysis of real-time signalling data can provide valuable insights into the hemi-equilibria that can occur in low receptor reserve systems with agonist-antagonist interactions, due to...
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"The contribution of an imbalanced redox signalling to neurological and neurodegenerative conditions" From @jrs1573 and colleague https://t.co/uo0pugmGQa
pubmed.ncbi.nlm.nih.gov
Nitric oxide and other redox active molecules such as oxygen free radicals provide essential signalling in diverse neuronal functions, but their excess production and insufficient scavenging induces...
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"Endocannabinoid hydrolases differentially distribute in platelets and red blood cells and are differentially released by thrombin" From @mqzspa and colleagues https://t.co/6Zgq8c9Khp
pubmed.ncbi.nlm.nih.gov
These investigations suggest a potential role for FAAH in regulation of coagulation, while the role of MAGL in blood requires further investigation.
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"Perceived stress as a predictor of eating behavior during the 3-year PREVIEW lifestyle intervention" From Moira Taylor and multiple colleagues https://t.co/N1vRzEzfwu
pubmed.ncbi.nlm.nih.gov
Perceived stress was associated with features of eating behavior that may impair successful weight loss maintenance. Future interventions should investigate, whether incorporating stress reduction...
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We're delighted that seven of our researchers are named among @Clarivate's top 100 Highly Cited Researchers of 2022. Congratulations to all of those who have been recognised for their outstanding work and influence in their fields. https://t.co/VEELwxi3lV
#WeAreUoNResearch
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Come join us in Nottingham for a great Team Science PhD experience: https://t.co/E5hGVNN75A
findaphd.com
Apply for a PhD: Wellcome Trust 4-Year Doctoral Training Programme in Drug Discovery and Team Science at University of Nottingham
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@PPNNottingham I have just received this message: "We are pleased to inform you that your paper, ( https://t.co/ED86hD3RN5), has been downloaded 2076 times, meaning that it has been selected as one of the Top Downloaded Papers of IJMS in 2021. Congratulations!"
mdpi.com
Muscle fatigue (MF) declines the capacity of muscles to complete a task over time at a constant load. MF is usually short-lasting, reversible, and is experienced as a feeling of tiredness or lack of...
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@jeanettewoolard describing how Team Science has contributed to success in @COMPARE_UoBUoN and @PPNNottingham
#pharmacology2022 @BritPharmSoc
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Congratulations to Professor Sir Jonathan Van-Tam, who receives the David Attenborough Award and Lecture for his role in public engagement during the COVID-19 pandemic as UK Deputy Chief Medical Officer, through national and international media. #RSMedals
https://t.co/D9X5u52nAT
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"Simple methods for quantifying super-resolved cortical actin" From @Hebdomadian and colleagues https://t.co/QaBWhD2ZtB
pubmed.ncbi.nlm.nih.gov
Cortical actin plays a key role in cell movement and division, but has also been implicated in the organisation of cell surface receptors such as G protein-coupled receptors. The actin mesh proximal...
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"Acute effects of prior dietary fat ingestion on postprandial metabolic responses to protein and carbohydrate co-ingestion in overweight and obese men: A randomised crossover trial " From @kostas_tsintzas and colleagues https://t.co/DOsvjmCO20
pubmed.ncbi.nlm.nih.gov
ClinicalTrials.gov Identifier NCT03146286.
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"Detergent-Free Membrane Protein Purification Using SMA Polymer" From @IankerrS and colleagues https://t.co/tSrNEZ5f3S
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