Neil Kelleher
@NLKProteomics
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The official twitter acct for Dr. Neil Kelleher, the Faculty Director of Northwestern Proteomics & Director of the Chemistry of Life Processes Institute.
Evanston, IL
Joined May 2018
Another strong showing from our great team at #ASMS2025. Come check out our talks and posters! My poster on our endogenous Ab sequencing platform is Tuesday. See you there! #proteoforms #TeamMassSpec
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In today's The Analytical Scientist, @NLKProteomics calls for a Human Proteoform Project to bring protein-level precision to medicine — just like the Human Genome Project did for DNA. https://t.co/r3RyMnOTKl
#Proteomics #PrecisionMedicine @tAnaSci
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Published today in @NatureBiotech, this is a pretty impressive biomedical breakthrough by @PeiSu7 and our colleagues in the lab. We're now able to able to map the #proteoforms of a brain cell in extraordinary detail! A link to the paper is in the comments below.
What if we could directly measure proteins in single brain cells—no labels, no tricks? 🧠 @NorthwesternU scientists just did it, profiling 10,000+ cells using #scPiMS, a breakthrough in single-cell proteomics. @NLKProteomics
https://t.co/kF5qxRNpSy
#MassSpec #Neuroscience
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Today, as we celebrate #NationalProteoformDay, we're thinking about this 2021 publication in @ScienceAdvances that introduced the world to the Human Proteoform Project #HPfP. Understanding #proteoforms is essential to understanding our biology and harnessing it for the better for
science.org
An ambitious initiative is proposed to generate a definitive reference set of human proteoforms.
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It was an honor to give the annual lecture honoring #ProfJohnFenn at @VCU Virgina Commonwealth University #VCU last week. Thanks to his #Nobelprize winning work, we fly elephants every day!
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Friends, This is your early reminder that #NationalProteoformDay is coming soon! May 11th! (Which just happens to be the birthday of my friend and mentor, Fred McLafferty!) We're working on a fun plan for that day, which we will share with you! See you here on National Proteoform
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I've got your next generation of scientists right here! Had a great time at the Spectroscopy Society of Pittsburgh / Society of Analytical Chemists of Pittsburgh monthly meeting with these fine folks!
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A new study by Northwestern researchers @NLKProteomics and Daniela Ladner, MD offers new insights into how liver cirrhosis progresses and how it can be monitored more effectively. https://t.co/3ghsBDksiv
#cirrhosis @proteomics
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#HAPPYHOLIDAYS from the KRG / PCE holiday party! May your 2025 bring you strikes and spares! No gutterballs!
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Very proud of the work @eleonora_forte and @NM_Transplant for their work defining #Proteoform changes in liver cirrhosis. Early detection is key for promoting healthier livers and requiring fewer transplants. https://t.co/G3gkk3sIic
mcponline.org
In BriefCirrhosis affects 2 to 5 million Americans, with many developing severe complications. Identifying patients at high risk is crucial. Using top-down proteomics, we found 209 differentially...
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I'm not leaving this site just yet. But I've also set up a new base of operations over here: @nlkproteomics.bsky.social
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I'm pretty excited to announce that @TopDownProteome has launched a #Youtube channel where you can hear about the latest innovations in #TopDown #Proteomics from experts in the field. You can check it out here: https://t.co/gmd7AWjysk
#Proteoform
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Stanford Healthcare Innovation Lab recently invited @CLP_Institute director Neil Kelleher to speak about Digitizing Proteoform Biology with Single Molecule & Single Cell Mass Spec. You can view his talk here: https://t.co/K6aGFOZVwH
#proteomics @NLKProteomics
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Honored to speak to @WorldHUPO about the importance of the Human Proteoform Project. Mapping the full diversity of human #proteoforms will revolutionize protein biology and transform health for the benefit of all.
In his Plenary talk today, @NLKProteomics briefed #HUPO2024 attendees about the Human Proteoform Project, a big science initiative to capture the Proteoform Dynamics of Life in our bodies with complete molecular specificity. https://t.co/zpjDtEEuRp via @YouTube
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Join us at #HUPOWorldCongress to discover the latest innovations in proteomics! @M_L_Carpenter & @NLKProteomics from @NorthwesternU will be presenting how Next-Generation Protein Sequencing combined with top-down mass spec is transforming #proteoform analysis. #HUPO2024
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Had a great conversation with @paragmallick about the #proteoform . Short version: we need to sequence the human #proteome, like we did the #genome 20 years ago! #Proteomics #Biotech #Science
The active forms of proteins found in biological systems aren't simple strings of amino acids, but are the single-molecule products of many processes including splicing, phosphorylation, ubiquitination, and more. These "proteoforms" drive biology and thinking about them leads to
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I'm really enjoying the world-class science program at the Chicago BioEngineering Conference! Thanks to @ShanaOKelley, @SavasTay_UChi and the excellent @czbiohub team for hosting. #proteomics #proteoform #CZBiohubCHI
We’re excited to kick off the Chicago BioEngineering Conference today at #CZBiohubCHI, hosted by @ShanaOKelley and @SavasTay_UChi! It will be a great gathering of trailblazing scientists and engineers who are developing the #tech of today and tomorrow.
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It's a huge honor to share the stage with these guys. Thank you @Proteinsociety.
Congratulations to our 2024 Award Winners! We are incredibly proud to recognize their contributions to the field of Protein Science! Carl Brändén Award - Professor Tamir Gonen (University of California, Los Angeles) Christian B. Anfinsen Award - Professor Neil Kelleher
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I'm super excited to be at #PS38 in beautiful #Vancouver to accept the Christian B. Anfinsen Award and talk #proteinscience! Thanks @ProteinSociety!
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