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MolBioMed Profile
MolBioMed

@MolBioMed

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MolBioMed (Molecular Biomedicine) is a Computational and Theoretical Chemistry Research Group at the @qfuab, @FCienciesUAB, @UABBarceloa

Cerdanyola del Vallès, España
Joined May 2020
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@MolBioMed
MolBioMed
8 months
🎉 Durant els últims mesos s’han incorporat al grup l'Alba Villar Yanez (@AlbaVillarYanez) com a investigadora postdoctoral per treballar en fàrmacs fotoactivables i el Pedro Martínez Zaragoza com a investigador predoctoral per treballar en càncer i inflamació! Benvinguts!💪
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@MolBioMed
MolBioMed
10 months
🚨 Today, Pedro Martínez Zaragoza presented his Master's Thesis at UB: "Allosteric regulation of hALOX12 catalysis of 14S-HpDHA epoxidation/oxygenation competitive pathways." A groundbreaking contribution to understanding enzyme regulation in lipid metabolism! 👏
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@aperezs_
Álex Pérez Sánchez
11 months
🎄 Excited to share that my first scientific paper is published today on Christmas! 🎉 It’s now available in Protein Science: https://t.co/1Q1c01tgl4 Wishing you all a Merry Christmas! 🎅✨
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onlinelibrary.wiley.com
Cyclooxygenase-2 (COX-2) plays a crucial role in inflammation and has been implicated in cancer development. Understanding the behavior of COX-2 in different cellular contexts is essential for...
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@MolBioMed
MolBioMed
1 year
🎓 Last week, Susana and Guillem successfully presented their Bachelor's final thesis on Chemistry! 🧪✨ We're incredibly proud of their hard work and dedication. Congratulations to both of you on this remarkable achievement! 👏🎉 #Chemistry #ThesisDefense
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@aperezs_
Álex Pérez Sánchez
1 year
Last week, I presented at the 9th European Workshop in Lipid Mediators in Edinburgh! As the only computational chemist, it was fantastic to share my work and learn from field experts. Thanks to the organizers for the travel grant! Excited to apply what I've learned! #9EWLM
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@MolBioMed
MolBioMed
1 year
Today, our former member Alejandro Cruz presented his research on GPCR allosteric modulators at the @espa2024 conference. He came from the University of Southern California, where he is doing his postdoc. It was an excellent talk!
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@aperezs_
Álex Pérez Sánchez
1 year
Excited to share the progress of my ongoing research, "Unraveling the Activation of EP4 Receptor by Prostaglandin E2," at @espa2024! Looking forward to insightful discussions and feedback. #ESPA2024 #ScientificResearch #Receptors #Inflammation
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@j2ifam2024
J2IFAM 2024
2 years
Now is the turn of Álex Pérez, from Universitat Autònoma de Barcelona. His oral communication is related with “Understanding COX-2 for the Design of New Cancer Drugs: Computational Study with Specific Photochromic Compounds” #J2IFAM2024
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@MolBioMed
MolBioMed
2 years
⚠️📢 First paper of 2024 out! @ACSCatalysis Theoretical Study of the Arachidonic Acid Conversion into Leukotriene A4 Catalyzed by Human 5-Lipoxygenase: Hydroperoxidation and Epoxidation Mechanisms and Arachidonic Acid Active Site Access https://t.co/06R5hM9ZRE
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pubs.acs.org
Inflammation is at the base of many different diseases. Leukotrienes (LTs) are pro-inflammatory mediators derived from arachidonic acid (AA), which play significant roles in acute inflammation....
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@MolBioMed
MolBioMed
2 years
Congratulations to @mikicanyellesn on successfully defending his thesis! 🎓🥳 Our research group is proud to announce that we have a new Doctor in the house! 🌟 #PhD
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@aperezs_
Álex Pérez Sánchez
2 years
Excited to present my first poster at #EuChemSCompChem2023 in Thessaloniki, Greece! 🇬🇷 Sharing insights and connecting with fellow researchers in the world of computational chemistry. #ScienceNetworking #ResearchJourney
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@MolBioMed
MolBioMed
2 years
⚠️Check our last paper! @IJMS_MDPI Functional Characterization of Mouse and Human Arachidonic Acid Lipoxygenase 15B (ALOX15B) Orthologs and of Their Mutants Exhibiting Humanized and Murinized Reaction Specificities https://t.co/eHzS4zkI7r
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mdpi.com
The arachidonic acid lipoxygenase 15B (ALOX15B) orthologs of men and mice form different reaction products when arachidonic acid is used as the substrate. Tyr603Asp+His604Val double mutation in mouse...
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@MolBioMed
MolBioMed
2 years
Today Pedro Martínez presented his Bachelor's Degree Final Project entitled: "Exploring 14S-HpDHA binding modes and its negative allosteric modulation in hALOX12-catalyzed MaR1 biosynthesis". If you want to know what it was about, follow this link: https://t.co/Ri9MyRjWEh
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@MolBioMed
MolBioMed
3 years
This paper is part of the Special Issue "Lipid Signaling and Metabolism in Inflammation-Associated Diseases", edited by Prof. Dr. Hartmut Kühn via @IJMS_MDPI https://t.co/QgPEzpL2No
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mdpi.com
Special Issue in journal International Journal of Molecular Sciences: Lipid Signaling and Metabolism in Inflammation-Associated Diseases
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@MolBioMed
MolBioMed
3 years
⚠️📢New paper out! @IJMS_MDPI Hydroperoxidation of Docosahexaenoic Acid by Human ALOX12 and pigALOX15-mini-LOX by M. Canyelles-Niño (@mikicanyellesn), À. González-Lafont & José M. Lluch https://t.co/lkYipmeEm4
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mdpi.com
Human lipoxygenase 12 (hALOX12) catalyzes the conversion of docosahexaenoic acid (DHA) into mainly 14S-hydroperoxy-4Z,7Z,10Z,12E,16Z,19Z-docosahexaenoic acid (14S-H(p)DHA). This hydroperoxidation...
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