Deadline Extended for the Ramzi S. Cotran Young Investigator Award! Applications are due Wednesday, October 29. Apply or nominate a colleague today! https://t.co/MIScm8XPgG

Join Dr. Henry Tazelaar for a free Facebook Live broadcast from the Palm Springs Interactive Center on Non-Neoplastic Lung! Friday, Oct. 24 11:10 AM - 12:40 PM Pacific. https://t.co/mW7DMMdJTX

trainees waiting around to find out if their #USCAP2026 abstract will be accepted (I kid of course…bc having been on @TheUSCAP abstract review board in the past, I can vouch how seriously they take timely review💪🏽& letting folks know result)

Benign nerve sheath tumors are varied and interesting. This is an example of a schwannoma with neuroblastome-like features - perfectly innocuous. 1: Dehner CA, et al. Beyond Hybrid Morphology: A Large Series of Fusion-Driven Benign Peripheral Nerve Sheath Tumors Including 5

There are always new looks at classic entities in Modern Pathology. However, some things do not change; this dermatofibrosarcoma protuberans has tracked along connective tissue septa to involve the deep margin. The repetitive storiform pattern is characteristic. Smith SC,

Dermatofibrosarcoma protuberans survival. Molecular testing can be informative! Yeung MCF, et al. Comprehensive Clinicopathological and Multiomics Characterization of Dermatofibrosarcoma Protuberans Revealed PDGFD Fusion as Distinct Molecular Subtype With Better Survival. Mod

The #ESPCongress has begun, and you can find me @TheUSCAP booth in Exhibit Hall 4. Please stop by if you are attending! You can learn about all that USCAP has to offer the international pathology community. #PathTwitter

This Ewing sarcoma arose in the bladder. NKX2.2 has been around for some time and can be helpful in confirming the diagnosis despite imperfect specificity. Hung YP, Fletcher CD, Hornick JL. Evaluation of NKX2-2 expression in round cell sarcomas and other tumors with EWSR1

There is tremendous morphologic and genetic overlap between aneurysmal bone cyst, myositis ossificans, and nodular fasciitis, highlighted in Modern Pathology. This is an example of an aneurysmal bone cyst that protruded into the soft tissue. Zhang L, Hwang S, Benayed R, Zhu GG,

Another Modern Pathology classic - Miettinen M, Sarlomo-Rikala M, Sobin LH. Mesenchymal tumors of muscularis mucosae of colon and rectum are benign leiomyomas that should be separated from gastrointestinal stromal tumors--a clinicopathologic and immunohistochemical study of

In traumatic neuromas, the individual nerve packets are each cuffed by perineurium. A vintage Mod Pathol study demonstrated this. Hirose T, Tani T, Shimada T, Ishizawa K, Shimada S, Sano T. Immunohistochemical demonstration of EMA/Glut1-positive perineurial cells and

This pancreatic ductal adenocarcinoma spread to the ovary despite negative frozen section margins! Well, duh, the two are unrelated. Folks, we are wasting time on those stressful frozens for essentially no benefit to patients - read all about it! Li X, Malik P, Bhalla A,

Serotonin-producing pancreatic neuroendocrine tumors have a peculiar sclerotic background that is a clue to the diagnosis. Depoilly T, Leroux R, Andrade D, Nicolle R, Dioguardi Burgio M, Marinoni I, Dokmak S, Ruszniewski P, Hentic O, Paradis V, De Mestier L, Perren A, Couvelard

Classic pleomorphic adenoma; modern techniques buttress and expand upon what we have learned on good old hematoxylin and eosin staining. Jurmeister P, Leitheiser M, Arnold A, Capilla EP, Mochmann LH, Zhdanovic Y, Schleich K, Jung N, Chimal EC, Jung A, Kumbrink J, Harter P,

This peripheral type intrahepatic cholangiocarcinoma shows loss of BAP1 and reactivity with in situ hybridization for albumin. Learn more about it in this classic from Modern Pathology. Akita M, Fujikura K, Ajiki T, Fukumoto T, Otani K, Azuma T, Itoh T, Ku Y, Zen Y. Dichotomy

So many fusions - so little time. This gastric glomus tumor resulted in a hyperplastic polyp that underwent gastritis cystic profunda changes. Iwamura R, Komatsu K, Kusano M, Kubo C, Inaba Y, Shiba E, Nawata A, Tajiri R, Matsuyama A, Matoba H, Koga K, Takeda M, Itami H, Hisaoka

We would wonder where this hepatocellular carcinoma with large nuclei would lie in the model reported this month: Patil A, Hasan B, Park BU, Smith L, Sivasubramaniam P, Elhalaby R, Elessawy N, Nazli S, DaCosta A, Shabaan A, Cannon A, Lau C, Hartley CP, Graham RP, Moreira RK. A

H3K27me3 loss is good but not perfect for confirming a diagnosis of malignant peripheral nerve sheath tumor; this one arose in a diffuse neurofibroma. 1: Schaefer IM, Fletcher CD, Hornick JL. Loss of H3K27 trimethylation distinguishes malignant peripheral nerve sheath tumors from

Back to some basics. Leiomyosarcomas are amongst the sarcoma types that spread to lymph nodes, a phenomenon that is interesting to see.