MIT Glycobio Club
@MITglycobio
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A trainee-run journal club (est 2018) @MIT that explores advances in #glycobiology #glycotime (tweets by @dsyangta @vicmarando @sunhee_bae_ @AdeleGabba)
Cambridge, MA
Joined March 2019
Two postdoctoral associate positions are available in the laboratory of Dr. Fikri Avci at Emory University.
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This reminds me to mention that @KiesslingGroup has postdoctoral positions for researchers interested in using synthetic chemistry to study immunology and microbiology #chempostdoc.
Professors, I am begging you - please stop using the chemjobs tag for postdoctoral positions and PhD studentships. Instead, use the chempostdoc tag.
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The 2022 "All Hands Meeting" of the NIH Common Fund Glycoscience Program will be videocast live May 2: https://t.co/tVPEe7XQwB May 3: https://t.co/ZHeOJzyEiT May 4: https://t.co/g7hY8aWQfJ
@Glyco_Alps @glycoworld @glyconet_nce
@MITglycobio @acs_carb @GFRGlyco
#Glycotime
videocast.nih.gov
The NIH Common Fund Glycoscience Program is focused on creating new methodologies and resources to study glycans, and to develop these resources so they may be more easily understood and accessed by...
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Just a reminder that this event will be happening tomorrow. Please DM us if you would like to attend the meeting.
On April 6 at 12 pm (EST), we will be joined by Dr. Melanie Walker from @lab_mercurio to share the recent work on distinct glycosylation profile of breast cancer stem cells.
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Edit: this meeting will be taking place on March 30th (Wednesday) at 1pm EST
On March 31 at 1 pm (EST), we will be joined by @LukasGajdos2 from @AnneImberty Lab to share the recent work on using neutron crystallography to reveal details on how Pseudomonas aeruginosa binds to the host cells.
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On April 6 at 12 pm (EST), we will be joined by Dr. Melanie Walker from @lab_mercurio to share the recent work on distinct glycosylation profile of breast cancer stem cells.
science.org
A specific cell surface glycan enables the identification of breast cancer stem cells and contributes to their function.
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On March 31 at 1 pm (EST), we will be joined by @LukasGajdos2 from @AnneImberty Lab to share the recent work on using neutron crystallography to reveal details on how Pseudomonas aeruginosa binds to the host cells.
nature.com
Nature Communications - Pseudomonas aeruginosa employs lectins to bind to its host cells, and is known to be the major cause of lung infections. Lectin B (LecB) from Pseudomonas aeruginosa binds...
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We have two amazing glycobiology talks lined up for the coming weeks. 🍭 🍭 DM us for the zoom link. #glycotime
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📅Join us on Thursday 10th March for our glycobiology webinar at 3 pm GMT. Exciting talks by Alexandra Males & Yan Liu #glycotime Registration here: https://t.co/1dklMJmzcF
@Glyco_Alps @GlycoNmr_Bilbao @glycoworld @glyconet_nce @InnoglyA @MITglycobio @glyco_pm @GFRGlyco
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Please DM us if you are interested in joining the meeting.
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We are very excited to virtually host Dr. Xiaoxue Zhou (currently at MIT) on March 9 (1pm EST) to share her graduate work on C. glutamicum cell wall assembly. https://t.co/siA3Vyth8C 🦠
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MITGlycoBio club is excited to virtually host Roger Riera from Eindhoven University of Technology to discuss his recent paper on imaging glycan-lectin interaction. The meeting will take place on Jan. 31st at 1PM. DM us for the zoom link! #glycotime
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WOO for Wuo!🎊 @mike_wuo et al design a new probe to discover how the mycobacterial cell wall rearranges itself in the presence of antibiotics. Why won't the lipid bilayer just let these antibiotics in?? Find out here: https://t.co/RrDy2v5019
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Duke et al. used galactose oxidase for site-selective oxidation of C6 primary hydroxyl on the terminal galactose residues in CPS. Immunization with the homogeneous glycoconjugate displayed an improved humoral response.
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The traditional method for CPS derivatization involves periodate oxidation to generate aldehyde reactive groups for functionalization with carrier proteins. However, the method suffers from heterogeneity as well as structural changes and degradation of CPS.
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Polysaccharide antigens alone only elicit short-lived IgM antibody response since they cannot be displayed by the MHCII. However, covalent conjugation of polysaccharides to protein carriers can be presented by MHCII to trigger CD4+ T cells activation.
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The capsular polysaccharide (CPS) of Streptococcus pneumonia, a pathogenic bacteria with multiple serotypes, is known to be important for virulence and immune evasion. Thus, the current pneumococcal vaccine formulations use CPS as antigens.
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Thank you Jeremy Duke from the lab of Fikri Avci for a great talk last week. Jeremy shared a recent work on harnessing galactose oxidase in the development of a chemoenzymatic platform for glycoconjugate vaccine design. 🦠💉 https://t.co/HtWK56r468
jbc.org
In the preparation of commercial conjugate vaccines, capsular polysaccharides (CPSs) must undergo chemical modification to generate the reactive groups necessary for covalent attachment to a protein...
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Jeremy Duke I can't wait for your glyco-immunology talk! Join the @MITglycobio TODAY at 1 pm EST. DM for zoom link!
MITGlycoBio Club is excited to host Jeremy Duke from the lab of Prof. Fikri Avci at the University of Georgia on Dec 15 at 1 pm EST. Jeremy will be sharing his recent work on development of glycoconjugate vaccine. DM us for the zoom link.💉
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