Anna Ledwith
@LedwithAnna
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Immunology PostDoc at Trinity College Dublin/UCD | interested in obesity and cancer immunology
Joined January 2020
New paper alert! 🥳We are so proud to share this amazing work from the lab led by @SarahA_Connolly and @aaronbreathnach. In this study, we show that the BTN162b2 mRNA vaccine induces anti-inflammatory trained immunity in humans 💉💉Read more here: https://t.co/U9rfqRalfM
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Pleased to share our latest paper in @ScienceAdvances on myeloid cell ‘trained hypercoagulability’! 🚀 Project led by @AislingRehill - huge thanks to our collaborators & funders @IrishCtrVascBio @RCSI_Irl @tcddublin @Researchirel @hrbireland @CHIatCrumlin!
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Deep in scientific mode vs relaxing after a wonderful conference @iSTIIIMDD in Dresden. Wonderful opportunity to present some of the data I've been working on in #TrainedImmunity. Massive congratulations to @LedwithAnna for a fantastic presentation and winning a travel award 🎖️
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If you're interested in how dietary supplements can protect against viral infections I will be presenting some of my PhD data at #ECI2024! 🦠🔬 Talk at 5pm in the Viral Immunity section on Tuesday the 3rd of September
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My very first-author work as just been published in Americal Journal or Reproductive Immunology! This work has started during the 2020 lockdown and made me realise how much database investigation can help gaining insights about evolution of immune genes!
onlinelibrary.wiley.com
Problem The interleukin-17 (IL-17) family includes pro-inflammatory cytokines IL-17A-F with important roles in mucosal defence, barrier integrity and tissue regeneration. IL-17A can be dysregulated...
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Excited to share our new publication in @EurJImmunol. We have shown that IL-17A-producing Vγ4 γδ T cells are regulated by PD-1 in the EAE model. Thanks to @MillsKingston for the support and supervision as well as Caroline Sutton and Barry Moran @tcdflow
https://t.co/Orm65rpe60
onlinelibrary.wiley.com
PD-1 signaling suppresses IL-17A production by TCR-activated CD27− Vγ4 γδ T cells. Anti-PD-1 treatment exacerbates experimental autoimmune encephalomyelitis by enhancing IL-17A production by CD27−...
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Introducing the STEM book club! 📚🧬 Our goal is to foster enriching conversations and a deeper appreciation for the scientific wonders that shape our world. Join us for our first event in the Hole in the Wall, 5th of August, where we will be discussing Humanology ✨📚
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Delighted to see the work finally published! Mammoth effort from @chjohnston11 - excited for more to come!
Finally out there - Recognition of yeast β-glucan particles triggers immunometabolic signa... https://t.co/mWpxzv51QF Tweetorial Follows (1/12)
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Finally out there - Recognition of yeast β-glucan particles triggers immunometabolic signa... https://t.co/mWpxzv51QF Tweetorial Follows (1/12)
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Joining us for the 3rd biennial Sex Differences conference? There are just over 30 days to submit your abstract! Register now at https://t.co/aCz38cpe0C to be in with a chance of securing a travel grant for junior scientists - generously supported by @EFIS_Immunology & EJI.
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Very proud of @chjohnston11 presenting his PhD work on b-glucan induced anti-viral trained immunity at @bsicongress !🦠🍄 #bsi23
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Professor Cliona O'Farrelly has today been named a 2022 @aaas Fellow. Cliona has been honoured for her outstanding achievements as a researcher in the field of comparative immunology. Read more at: https://t.co/HA1EKDjR0b
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Please check out our new paper just published in @CellRepMed - We show that for polymeric particulate adjuvants size matters! https://t.co/hjXV4IC7JH We demonstate the size dependant adjuvanticity of polymeric particulate adjuvants and uncover the underlying mechanisms ⚙️ (1/4)
cell.com
Muñoz-Wolf et al. show that particle size dictates the induction of cell-mediated immunity by polymeric nanoparticulate adjuvants, identifying 50–60 nm as the optimal size for induction of Th1/CD8+...
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Our paper on in situ barcoding using a synthetic VDJ recombination (Diversity through RAG) approach is out now on biorxiv. More details in Leila's thread below!
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It’s published🎉! It will be hard for me to focus on my cardiology final today with my brain thinking about this🙃 If you want to learn more about trained immunity & pregnancy complications, here is the link: https://t.co/IY0OIkrppg
@MDPIOpenAccess @CharlesHGraham @SGPlacenta
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Our paper on innate resistance to hepatitis C virus infection is out in @CellRepMed this weekend! https://t.co/nRkv2mvFtL 1/12
cell.com
Natural resistance to infection is an often-overlooked outcome after exposure to HCV. Here, Sugrue et al. describe HCV resistance in a cohort of women accidentally exposed to HCV in the 1970s and...
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Inaction on Monkeypox tells us Ireland is not prepared for the next pandemic - @ClionaOfarrelly and I in the @IrishTimes today https://t.co/hjNMTQcvlz
irishtimes.com
No details about when vaccine roll-out will start, who will be responsible for administering it nor where they would take place have been provided
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