Spiegelman Lab
@LabSpiegelman
Followers
4K
Following
361
Media
57
Statuses
341
We study metabolic pathways regulating energy homeostasis, mitochondrial biogenesis, and muscle/adipose biology @DanaFarber @HarvardCellBio
Boston, MA
Joined May 2021
Cardiac PGC1a is required for adaptations of the heart to exercise (in mice). A wonderful collaboration with the lab of Tony Rosenzweig. Sumeet is off to start his won lab at UVa (congrats!)
2
12
78
0
2
11
Davo was a fantastic cook. This is after our last fishing adventure is June 2025
2
0
30
The passing Of Dave Mangelsdorf is a terrible loss for his family, friends and the science world. Davo will never be forgotten. 😢 https://t.co/JQzVDG9RWS
7
27
127
Matt Gilbert and Krys Seremak cartooning the boss's favorite saying at lab meetings 🤣
0
2
38
Without its international students, Harvard is not Harvard.
harvard.edu
We have just filed a complaint and a motion for a temporary restraining order will follow. As we pursue legal remedies, we will do everything in our power to support our students and scholars.
21K
16K
92K
Another great Spiegelman Lab Retreat goes in the record books. Everybody gives a talk, but it can't be what you work on! Stretch the mind.
3
3
94
What a great occasion! Our Visiting Student Alex Braunsperger and Paulina Braunsperger-Wasserfurth tie the knot, Bavarian style. Heartly Congrats!
0
5
54
A new discovery from the bowels of the DFCI CB business office. I'm gonna say Jae Bum Kim and Peter Sellers from The Pink Panther movie?
1
3
62
Yay Shingo! • Shingo Kajimura, PhD is the recipient of the 2025 Outstanding Scientific Achievement Award of the ADA, which recognizes research in diabetes that demonstrates particular independence of thought and originality. @KajimuraLab
7
4
96
Hage Sprenger is back in Koeln, Germany starting his own lab. Check him out at @hagesprenger.bsky.social
0
0
6
Ergothioneine is an atypical amino acid to which many health benefits in humans have been ascribed. Here we determine the direct protein target of ergo binding and how it functions in mitochondria and exercise.
2
17
86
Does the lack of correlation between PGC1a RNA and protein give you a headache? Us too. Phillip Dumesic has uncovered a key factor controlling PGC1a mRNA translation
2
28
114
In the course of this work, we found that PGC1a has a critical role in keeping naked mito DNA out of cytoplasm, preventing cGAS/STING activation.
0
0
7
Wanna see what true love looks like in @labspiegelman? Here is Amanda Smythers with our new Mass Spectrometer, timsTOF!
4
11
399
Figured BlueSky(s) were better for fishing 🤷♀️Find us at @spiegelmanlab.bsky.social!
0
0
3