The Seale Lab (UPenn)
@LabSeale
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We study thermogenic fat and we have fun doing it! Account managed by lab personnel. Opinions are our own.
Philadelphia, PA
Joined September 2019
Excited to share our new manuscript @MolMetab This study led by @CAMBUpenn graduate student Libby Nunn explores the potential of activin type II receptor blockade to maintain muscle mass and enhance fat loss during GLP1RA in obese mice
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Also, in the same issue, check out this excellent complementary story led by @JyotiRao_ and Olivier Pourquié, tying together brown fat development in mice and humans!
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Excited that our most recent work was featured as the cover story in this recent @Dev_Cell issue! Congrats to @seoyoung_jun @AnthonyAngueira @EthanFein who spearheaded this work and special thanks to @TanJosephine_ for contributing her microscopy skills! https://t.co/YRhpiPhmvG
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Congratulations to Josephine on her well-deserved honors at #NAVBO2023 !
Coming back from an inspiring #NAVBO2023, where I shared my work on SMCs in atherosclerosis. Very grateful for all the scientific exchanges and the two (?!) awards! See you next year! @vascularbiology
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How does embryonic #brownfat develop? Very excited to share our recent findings in @Dev_Cell on GATA6, a crucial transcription factor required for Pparg expression and #brownfat development. Thanks so much to everyone involved! #adipocyte #obesity
https://t.co/uvnE25PG64
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Wonderful tribute for the late Dr. Franz Matschinsky by @KlausKaestner at #Kroc Spring Symposium
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We are very excited to announce the Thesis Defense of (soon to be Dr.) Corey Holman! All are welcomed to attend in person or virtually. DM if you would like a zoom link.
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Come see (virtually) our very own Corey Holman present her work!
NEXT WEEK! -Adipose Biology Seminar Series- ⏰February 28, 12pm-1pm EST 🎙️Dr. Chelsea Hepler from the Joseph Bass Lab @NUFeinbergMed 🎙️Dr. Corey Holman from @LabSeale @PennIDOM 💻Details on poster below 🌱Kindly supported by @MbD_UofT Please retweet!
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The lab had an amazing week @KeystoneSymp
#KSBioenergetics23 and #KSADIPOSE23. Great science plus some time on the slopes!
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Now that I have 100K followers, I want to talk about #OvarianCancer. Specifically my gritty story. The goal is awareness. I hope you find this narrative informative.
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Thanks for the shares! It is such an exciting time for the lab- lots of new projects in the works.
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Want to work with a great team of scientists studying adipose biology and metabolic disease? The Seale lab is looking for a research specialist to join us at UPenn in Philly. We have a very positive, collaborative environment. Please retweet/share! https://t.co/jN5jK6sn6w
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IDOM/DRC Seminar: Jan. 14, 2020 @ 4:00 pm Student Invited Speaker - Barbara B. Kahn, M.D. “The Biology and Mechanisms of Action of a Family of Bioactive Lipids that Protect Against Type 1 and Type 2 Diabetes”
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Proud to share our latest paper from the graduate work of the extraordinary @ClaireBensard, "Regulation of Tumor Initiation by the Mitochondrial Pyruvate Carrier", in collaboration with the Thummel lab, out in @Cell_Metabolism today https://t.co/HsMGZzF9gJ
#MPCforLife
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Dr. Carrie Burns an Associate Professor of Clinical Medicine @PennMedicine writes outstanding Op-Ed in @PhillyInquirer on Diabetes in Pregnancy. Check it out here -
inquirer.com
My 27-year-old patient, recently diagnosed with Type 1 diabetes, was worried about carrying a baby. We had a lot to talk about -- including information I hoped would allay her fears.
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1. These are my own personal 10 commandments of peer review: I the reviewer WILL write my review in a helpful, kind, & considerate voice. I will NOT sound angry, be snarky, make derogatory comments, be rude, be dismissive, or be condescending.
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The Friedman lab is ready to grow! We’re looking for a postdoc/sr research associate with an interest in mitochondria and structural/biochem approaches. We've got a great project in mind and world class facilities at UTSW! Contact by email or come find me at ASCB. Please RT!
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Check out this great thread! Excellent resource for young scientists 😊
I finally went through all my bookmarked tweets to compile a list of resources I want my grad students to have and wanted to (1) thank everyone who posted these resources, and (2) pay it forward and share the compiled list with all of you!
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Adipocyte Hypoxia-Inducible Factor 2α Suppresses Atherosclerosis by Promoting Adipose Ceramide Catabolism
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