Our dear @KateDicker4 is leaving for a new adventure. Despite a pandemic & a lab move from @BiochemOxford to the @CVRinfo , she completed an excellent PhD and discovered a cellular protein that regulates HIV particle formation (stay tuned for the paper). We will miss you! 🍀🥲🥂

Corrections finally done and the leave to supplicate letter came through, it's officially Dr Dicker 🥳

🧵🧵 This work has been carried out as the @CVRinfo and @BiochemOxford, led by @ManuelGM87 and Robin Truman with crucial contributions from colleagues from the @castello_lab, @FranklinSystems , @ilandavislab and @emi_aeruginosa labs.

🧵We also elucidated the interactome of #Rev in HIV infected T cells. We show that many of the proteins that are packaged with the #HIV genome interact with Rev in the nucleus, likely remaining associated with the viral RNP until they are assembled into virions.

New preprint from the @castello_lab, showing that #HIV packages its genome with over 100 cellular #RBPs into viral particles. These proteins can play critical roles, e.g., PURA and PURB binds to key elements in HIV genome and enhances virion infectivity

Molecular components of the circadian clock regulate HIV-1 replication

Academia as depicted by…LOTR gifs: a thread.

Congratulations to @KateDicker4 that defended her PhD thesis on the discovery of new regulators of HIV infection, working in the @castello_lab and Sattentau lab 🎉🥳🥳🥳. Time to celebrate 🍻🍻

Great talk by @KateDicker4 from the @castello_lab on host RBPs that are encapsidated with the HIV genome! Unanticipated associations with interesting mechanisms that govern viral pathogenesis @RNASociety #RNA2022

@KateDicker4 from @castello_lab will talk on Saturday 4th in concurrent session 15 of the #RNA22 about our work on HIV and RBPs. Don't miss it!

The new Porter is doing a great job 👍🏻

how i imagine the lab exiting during an actual fire

An article I wrote on how yeast is being used to fight global health challenges has been published by @oxsci 😁 here's the link if you'd like to give it a read:

David Attenborough's credibility cannot be measured by human instruments. It is estimated to have a density beyond a neutron star and that a thimbleful of it would crush the earth. The books seem to snuggle in, joyful as they are crushed and absorbed. There is no greater honour.

You can't deny that @ExeterCollegeOx has the best view in Oxford! 📸Xuan Wang

Our response to the article published on Forbes online on 16th May by William Haseltine: