🚨 pleased to share a new preprint made possible through a great collaboration with the @melissa_skala & @SeanPalecek labs! can medium composition impact the behavior of hPSC-derived cardiomyocytes? Andy and Aaron co-led efforts to tackle this Q w/HPLM! https://t.co/s71Ygb2aVm
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by evaluating a broad array of phenotypes (structure, function, gene expression, metabolic activity, etc.) they found that hPSC-CM maturation was more effectively promoted by culture in HPLM vs conventional media!
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@JasonRCantor @melissa_skala @SeanPalecek Congratulations Jason! Is metabolic enhancement stable after HPLM withdrawal?
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@Ella_Maru @melissa_skala @SeanPalecek great q! i don't believe that the possible effects of 'withdrawal' (or shift to alternate conditions following the maturation period) have been tested yet, but this concept is perhaps worth exploring!
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