Our work describing how the thermodynamics of cotranslational folding differs from folding in isolation is now out in #Nature! #proteinfolding #ribosome #nmr #MD

It’s crazy how talking with a science buddy is simultaneously what’s most likely to move the project forward and the thing that’s least prioritized in our schedule.

New research suggests that #NFκB signaling is necessary to maintain #Xchromosome inactivation after T cell activation. Read more in @SciImmunology: https://t.co/lpNuOnOjFO

Biological Age Vs. Chronological age is often discussed in academic and public discourse. This article in @NatureMedicine is a good read to understand the use and misuse of various "Aging clocks" https://t.co/lMbO5m9hFU

How ribosomes shape protein folding

Check out the research briefing about our recent paper in @Nature. We describe how the ribosome shapes folding of its nascent proteins by integrating NMR experiments with all-atom molecular simulations: https://t.co/Cf6S7yn5G7 #NMRchat #compchem #compbio #proteinfolding #ribosome

A structural rationale for reversible vs irreversible amyloid fibril formation from a single protein:

Very nice article by @dmgerhard on “The Dynamic Lives of Intrinsically Disordered Proteins” with quotes from @G_T_Heller, @alexholehouse and myself about our shared love of and fascination with these proteins https://t.co/KUXVUVUkAD

We are hiring! Position open for a new assistant professor in the Department of Biophysics & Biophysical Chemistry in @HopkinsMedicine . Considering all areas in experimental and computational biophysics. Please spread the word. https://t.co/cAXosnT9rC

Published today in @Nature, we describe an approach for single-molecule protein reading on @nanopore arrays. By utilizing ClpX unfoldase to ratchet proteins through a CsgG nanopore, we achieved single-amino-acid sensitivity.

A feature in @NatureBiotech discusses the rise in team size in academic science and how it has generated an unintended side effect: junior scientists are less likely to secure research funding or obtain tenure and are more likely to leave academia. 🔒

It's often thought that in #Alzheimer, neurons produce Aβ, with more active neurons making even more, leading to neuronal dysfunction. But our research in @PLOSBiology shows that oligodendrocytes also produce a lot of (soluble) Aβ. This has been overlooked because most

Do you like to be a part of our research, including development of NMR methods and advanced application ? Then join the UCL Biomolecular NMR Facility as a facility manager in the Division of Biosciences @uclbiosciences Apply below #NMRchat https://t.co/upJiAbL1iN

📣 WE ARE HIRING (TT assist. or assoc. prof) Come be my colleague at the University of Copenhagen 🇩🇰! Copenhagen is a great city to live in 🚲🌤️ 👪 and you will have lots of great colleagues 🧑‍🔬🧑‍💼 working on diverse topics🧪🧫🧶🍝🧬🖥️ Deadline Sept 22: https://t.co/QgHtfvL6Vc

Nature research paper: The ribosome lowers the entropic penalty of protein folding

Ready to lead your own research team-?😎The Max Planck Society offers you the chance to head an independent Research Group at a participating Max Planck Institute of your choice - the next open topic call starts on Sep 9, 2024. Stay tuned for updates!🌟 https://t.co/FJME2GLVVc

Direct observation of prion-like propagation of protein misfolding templated by pathogenic mutants:

And very nicely explained how it came to be in Max Perutz’s biography ‘The Secret of Life’