A new study concludes that the Bayesian adaptive dosing strategy significantly improves the accuracy of achieving the target busulfan AUC in patients undergoing HCT. Published in British Journal of Clinical Pharmacology. | #Bayesian #AUC #HCT #Busulfan

Happy New Year! The InsightRX Team wishes you a safe and happy 2025! | #HappyNewYear #Happy2025

This recent study addresses the question, can we extract unrecognized #SADRs with known #PK mechanisms from biomedical literature using natural language processing tools & validate DDIs-SADR signals through multi-source EHR databases?. | @ASCPT_ClinPharm

A new study evaluates whether the pediatric selexipag dosage recommendation, based on the #PopPK model for adults, achieves similar drug exposures in #PediatricPulmonaryArterialHypertension (PAH) patients:

Wishing you a safe and happy holiday season from the InsightRX Team! #HappyHolidays #OurTeamToYours

A new study examines the link between #vancomycin supratherapeutic dosing & #AKI using a novel correlation factor equation. Key finding: All AKIs occurred with AUC <600—pharmacists should assess other AKI causes. Author: Yazan Batarseh, @HMCHospital:.

The goal of this study was to leverage ensemble learning approaches to develop physiological aging measures from point-of-care #biomarkers. Published in Pharmacometrics & Systems Pharmacology. ➡ | #PhysiologicalAge #PrecisionMedicine #PrecisionDosing.

In this editorial, scientists call upon the #ClinicalPharmacology & translational science community to collaborate across sectors & disciplines to be able to collectively transform the landscape of rare & neglected diseases. #RareDisease #ClinicalResearch.

In this episode of the Oncology Unplugged series, @CParkMD, @Norton Healthcare Cancer Institute, hosted a conversation with @VivekSubbiah, @SarahCannonDocs. Learn more via @OncLive: | #PrecisionMedicine #PrecisionOncology @MJHLifeSciences.

A new study demonstrates that the selection of an appropriate adult reference population is important for pediatric PK exposure matching & pediatric dose selection, especially for a drug substantially eliminated through renal excretion: | #Pharmacokinetics

A new study concluded that following the implementation of a pharmacist-driven #AUCMonitoring program, patients were less likely to develop nephrotoxicity during outpatient #vancomycin therapy. | #PrecisionMedicine #AntimicrobialTherapy @BrighamWomens

RT @PharmacoJournal: Over 380K vancomycin treatment courses were used to evaluate the predictive performance of various vancomycin PK model….

A new study aimed to identify the optimal PK/PD predictor and assess the correlation between AUC/MIC, trough concentration and the vancomycin efficacy in neonates. | #PrecisionMedicine #Vancomycin #Pharmacokinetics #Pharmacodynamics #PKPD

Stephanie Hughes, PharmD, BCIDP, joins Dr. Michael Rybak on the @ACCP Journal Podcast to discuss her study on #vancomycin #PKModels in diverse age & BMI groups. Learn how to apply insights from 380K+ treatment courses to your patients. 🎧 Listen now:

We’re pleased to announce that we will be presenting a research abstract at the @ASHPOfficial 2024 Midyear Clinical Meeting on Dec. 8-12 in New Orleans. Learn more: | #PrecisionMedicine #PrecisionDosing #CockcroftGaultEquation #PKPD #TherapeuticDosage

This study compares GFR models to the Mech-KiM model with hypothetical drugs and metronidazole (96% reabsorption). Dive into the findings in CPT: Pharmacometrics & Systems Pharmacology: . #Pharmacometrics #Pharmacology #Pharmacokinetics #PBPK

The InsightRX Team would like to wish you a safe and Happy Thanksgiving! We are grateful for all the clinicians working today and every day to keep their patients safe. #HappyThanksgiving #Grateful #Thankful

This recent study investigated which factors are associated with receiving pharmacogenetically targeted drugs & estimated cost-effects of untargeted pre-emptive #pharmacogenetic panel testing with #CostBenefitModel. @UniTurku @helsinkiuni @ASCPT_ClinPharm

A new study concludes that the combined CKD-EPICR-CYS performs best in terms of predicting pharmacokinetics of pemetrexed. Published in Cancer Chemotherapy and Pharmacology. | #Pharmacology #Pharmacokinetics #PrecisionMedicine #OncologyTreatments

@NIPERHyd @ASCPT_ClinPharm.