Kwon_Lab@JHU
@Hyungbae_Kwon
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Neuroscientist, Associate Professor at JHU, Memory tagging and reconstitution, Circuit assembly, Synaptic connectivity, Cognitive Learning, Tool development
Baltimore
Joined May 2024
See the amazing line up of speakers for the Catecholamines GRC! Apply for GRC https://t.co/Q9NL4ECZ7M & GRS https://t.co/hujWjNb7W4. In these uncertain times we appreciate any donation to support the participants in the GRC https://t.co/TeH1vGbA9M & GRS https://t.co/0IRaVNOAba
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Happy to share our latest review paper in Current Opinion in Neurobiology @ELSneuroscience! We overview “current” activity-dependent tagging systems in neuroscience and discuss the future perspectives. Feel free to download the PDF until April 27! https://t.co/csprNJj3hS
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🧠 Curious about neuromodulator interactions or how sleep works its magic? Apply to our lab @WashUMedNeuro as a postdoc to bridge cellular & systems neuroscience by decoding biochemical signaling dynamics in the brain! Please RT. #Neuroscience #PostdocOpportunity #BrainResearch
🚨Job Alert 🚨 Postdoctoral Research Associate (Chen Lab) @yaochen20’s interdisciplinary lab in the Department of Neuroscience at WashU Medicine seeks a motivated postdoctoral researcher to join the team. Learn more and apply: https://t.co/NSgK8l507y
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AstroLight: Cal-Light for Astrocytes🔥
An #astrocytic ensemble that emerges in the nucleus accumbens upon activity during cue-motivated behaviors and is essential for modulating cue-reward associations @llinas_marta @Irene_ish @crismonteagudo @CSIC @InstitutoCajal
https://t.co/PiTQtqFNUG
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Happy to share the lab’s latest research tagging psychedelic-activated neurons in mice. See the post below from first author @jessie_muir for a tweeprint on the work. Thanks to wonderful collaborators @DEOlsonLab @LinTianPhD and to our reviewers/editor! https://t.co/Gt6iGbLWdn
science.org
Psychedelics hold promise as alternate treatments for neuropsychiatric disorders. However, the neural mechanisms by which they drive adaptive behavioral effects remain unclear. We isolated the...
Excited to share the Kim Lab’s newest paper in @ScienceMagazine with Sophia Lin (twitterless) and @tinakim_neuro ! We look at circuit mechanisms of psychedelic action underlying therapeutic-like effects in the PFC. https://t.co/zqq96eLRHB
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Hyungbae Kwon, Ph.D., and colleagues have successfully used optogenetics to artificially reactivate a spatial-memory, prompting shelter-seeking behavior in mice without the original threatening stimuli that were present during the formation of the memory circuit. Their study
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Our behavioural time scale plasticity paper is out in @Nature ! Congrats @neuroAnant , Yoshi, and others! https://t.co/SwRmvRTnBJ
nature.com
Nature - Induction of behavioural time scale plasticity leads to dendritic, delayed and stochastic Ca2+/calmodulin-dependent kinase II activation, findings that clarify the mechanisms that...
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Why are some neurons more selective than others? We report now in @Nature how calcium permeable-AMPA receptors in PV neurons make them less selective to sensory features https://t.co/Y7sXbtE8I3 Long live the geniuses behind this🧠🔍 https://t.co/87BqmXxYje
@thainmueller @rhuganir
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Although further investigation is needed, the results also suggest that dopamine encodes safety or novelty in the environment, facilitating subsequent spatial learning even in the absence of rewards.
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We found that dopamine signals to the nucleus accumbens help form goal-location memories in mice, guiding navigation under threat. This task was made possible by the Cal-Light technique, which enables the tagging and control of individual cognitive modules.
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New publication alert! In this paper, we demonstrate causal evidence linking memory to behavior, even in complex, high-level cognitive navigation tasks. Huge congrats to a former postdoc @KanghoonJung, and collaborators @Sethblackshaw and @ruimcosta.
nature.com
Nature Neuroscience - Jung et al. show that shelter experience boosts dopamine release in the nucleus accumbens, generating a goal-location memory. Reactivating a neuronal ensemble developed from...
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Read about the latest circuit tools for studying neuromodulator & neuropeptide signaling in vivo! We describe the use of neurochemical sensors, actuators, and probes in our lab’s first Review @ScienceMagazine
https://t.co/GUfZfWPPhr Congrats @jessie_muir & @LatinaNeuroNerd!
Check out the Kim lab's latest review out in @ScienceMagazine featuring @LatinaNeuroNerd, @tinakim_neuro and myself! https://t.co/JYnfcQNWUI
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Job openings in Psych&Brain Sciences at JHU!
We also have a third opening in behavioral neuroscience:
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President and CEO @ruimcosta will be giving a Presidential Special Lecture at #SfN24! 📆 Sunday, October 6, 5:15–6:30 p.m. 📍 MCP Hall B 💻 Livestreamed via @sfntweets conference platform
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WHaloCaMP is a chemigenetic calcium indicator based on HaloTag that can be combined with different rhodamine dyes for multiplexed or FLIM imaging in vivo, as demonstrated in neuronal cultures, brain slices, Drosophila, zebrafish larvae and mouse brain. https://t.co/bL751a2Mg7
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Johns Hopkins University achieves its highest-ever position in the U.S. News & World Report rankings coming in at No. 6 for the nation’s best colleges for undergraduates. The @usnews report recognizes Johns Hopkins for its excellence in value, innovation, and undergraduate
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Thrilled to share our work on novo protein LYTAC(pLYTAC)/EndoTag in @nature! Using de novo protein design, we created endocytosis triggering binding proteins (EndoTags) to degrade extracellular targets and amplify receptor signaling.
nature.com
Nature - Computationally designed genetically encoded proteins can be used to target surface proteins, thereby triggering endocytosis and subsequent intracellular degradation, activating signalling...
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Super-excited to reveal our latest fluorescent voltage indicator, ASAP5, now online @NeuroCellPress! ASAP5 features higher responsivity and kinetics, allowing detection of single synaptic transmission events. The link gives free access until 2024.11.09: https://t.co/9GSeEyq0Fi
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In the 2025 Best Colleges rankings announced today, @usnews has once again named the Johns Hopkins Department of Biomedical Engineering’s undergraduate program as the best BME program in the nation.
bme.jhu.edu
U.S. News and World Report has once again been named the Johns Hopkins Department of Biomedical Engineering’s undergraduate program as the best program in the nation.
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