Hughes Lab - UCI
@HughesLabUCI
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The Hughes Lab at UCI. Developing blood vessels-on-a-chip and vascularized micro-organ (VMO) technologies to study vascular biology, cancer, and rare diseases.
Joined July 2020
Check out our 2nd place @NikonSmallWorld video. Images in our vascularized micro-tumor device, it shows microvessels (red) forming over time and growing micro tumors (cyan) as they respond to contact with those vessels.
This time-lapse video shows a human micro-tumour growing over 10 days in a lab. 🤯 The tumour, in blue, grows with the support of vessels, shown in red. Dr Stephanie Hachey and Dr Christopher Hughes were awarded second place for their video. @NikonSmallWorld @HughesLabUCI
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Any cardiovascular postdocs looking for a job? A tenure-track faculty position for cardiovascular research is open at LSU Health Shreveport. Excellent research infrastructure in a collaborative and supportive environment. Great place to start a lab. https://t.co/l10dZuEBrU
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Excited to share our organoid model of vascularized stem cell islets. Great teamwork led by @KVyNguyenNgoc and Yesl Jun. Thanks to @someshtweet, @HughesLabUCI, @steven_c_george, @ChristmanLab, @Hugh_Bender, @KravetsVira, @HIRN_CC . ď‚Ż 1/4 https://t.co/9P6ZLSBEQ7
biorxiv.org
Blood vessels play a critical role in pancreatic islet health and function, yet current culture methods to generate islet organoids from human pluripotent stem cells (SC-islets) lack a vascular...
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Our postdoc Steph is participating in the Anti Cancer Challenge at UCI this year to support junior scientists through @ARCS_OC. If you can take a couple minutes and make a donation to our cause Steph would be very grateful! https://t.co/XVBYpPng2e
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Our postdoc Jenn presenting our work on the HHT-on-a-Chip model at last night’s MPS-World Summit! Thanks to everyone for stopping by!
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Thrilled to have the opportunity to partner with @AracariBio @HughesLabUCI this week at #2022MPSWorldSummit to present a workshop to trainees discussing ways to allow physiology to inform development of micro physiological systems, and to demo the VMO platform!
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From left to right: Will, Chris, Sebastian and Makena — all incredibly talented grad students and enthusiastic scientists!
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Congratulations to our graduate students who presented an incredible joint poster at tonight’s MPS-World poster session!
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Our lab also has posters in Poster Session II on Thursday 6-8pm. We would love for you to come by and introduce yourself!
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In the first poster session, which will be Wednesday evening 6-8, we have several graduate student posters highlighting recent work on several of our healthy and disease #MPS models. Please stop by!
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Later this afternoon, you can catch Dr Hughes presenting our data on the vascularized micro-tumor platform at 3:40pm in Session III.
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We hope you were able to see our post doc Jenn this morning presenting a joint demo of our platform along with Will from @AracariBio!
Are you in New Orleans this week for the MPS-World Summit? So are we! Most of our lab is in town and we are presenting several posters and talks about our work! Please come by and say hi! https://t.co/sutrenx8O8
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Are you in New Orleans this week for the MPS-World Summit? So are we! Most of our lab is in town and we are presenting several posters and talks about our work! Please come by and say hi! https://t.co/sutrenx8O8
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Thank you so much @HIRN_CC for highlighting our work to develop a Vascularized islet-on-a-chip model, the culmination of many years of work by our team! @Hugh_Bender @msanderlab @steven_c_george @KimVyNguyenNgo1
Highlighting #HIRN manuscript: A vascularized 3D model of the human pancreatic islet for ex vivo study of immune cell-islet interaction @biorxivpreprint
https://t.co/NSdWEZrR7v
@allysonshughes @KimVyNguyenNgo1 @steven_c_george @msanderlab @HughesLabUCI
#HIRNFundedResearch
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Thank you! We are so excited to share this incredible work by our talented postdoc @Hugh_Bender!
Wonderful islet on a chip platform elevating islet culture conditions to include the #vasculature which provides functional support and models immune cell extravasation. Congratulations @Hugh_Bender @HughesLabUCI @msanderlab
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@BlumLabWisc @JimJohnsonSci We agree @BlumLabWisc ! It’s been fun to develop this together with @HughesLabUCI led by @Hugh_Bender .
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Congratulations to our postdoc Satomi Matsumoto for receiving an Outstanding Talk award at this year’s #NAVBO @vascularbiology!
➡️Outstanding Talk in the Vascular Matrix Biology and Bioengineering Workshop Suhaas Anbazhakan @suhaasaz Kaveeta Kaw from @DiannaMilewicz Lab Satomi Matsumoto from @HughesLabUCI Scott Paulissen @ScottPaulissen Michael Warkala @mwarkala
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Thank you! So excited to share our ideas!
Partial #EndMT & #Angiogenesis "Why do EndoMT transcription factors appear to be more essential in pathological angiogenesis compared to during development..." An insightful review from Dr. Christopher Hughes lab🤓 @HughesLabUCI @FrontCellDevBio 2021 https://t.co/WBQP5blsCL
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We’re so excited to present our latest work at @navbo #navbo2021 this week and hope you find this thread helpful in finding our research group members at the conference! Come say hi - we’d love to talk with you about our work!
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And last but certainly not least, don’t miss our illustrious leader Dr Chris Hughes when he co-chairs the Patterning and Morphogenesis I session tomorrow 10/27 at 2:00pm EST / 11:00am PST!
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