Gene and cell therapies have transitioned from the research frontier to clinical reality, reshaping the practice of modern medicine. Regulatory authorities across the United States, Europe and Japan...

Nature Reviews Clinical Oncology - Third-generation EGFR tyrosine kinase inhibitors such as osimertinib have substantially improved clinical outcomes in advanced-stage EGFR-mutant non-small-cell...

The WAVe stdudy- A multicenter prospective cohort study of wieght-adjusted dalteparin in patients over 90 kg with acute cancer-associated venous thromboembolism.

Abstract. De-escalation trials in oncology have received increased attention recently because there is a growing concern that patients with cancer are bein

The efficacy and tolerability of anticancer drugs may be affected by several factors that change with age. No specific trials of cabozantinib have been conducted in older patients with metastatic...

The Older Adults with Cancer Clinic (OACC) performs comprehensive geriatric assessments (CGAs) for patients aged ≥65 with cancer. To manage limited resources and increasing wait times, raising the...

Older patients with cancer are at increased risk for adverse drug events due to chronic conditions and complex medication regimens often leading to polymedication. A pharmacist-led medication review...

Sarcopenia is a term that defines muscle insufficiency [1]. It is associated with worse cancer prognosis (both increased risk of recurrence and cancer-related death [2]), higher rates of post-opera...

Electronic patient-reported outcome (ePRO) monitoring improves cancer treatment completion, quality of life (QoL), and is now covered by several French National Health Insurances. Given that most...

British Journal of Cancer - Experimental Cancer Medicine Centre (ECMC) network proposal for a consensus gene panel for pan-cancer sequencing: a Delphi methodology

Introductionwe present the case of the first documented occurrence of concurrent dermatomyositis and interstitial pneumonia associated with Trastuzumab Derux...