Michael Fessler, MD @FesslerMd X Profile

Michael Fessler, MD

@FesslerMd

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Senior Investigator @NIEHS Intramural. Physician scientist. Heads #innateimmunity #Fesslerlab in RTP, NC. #Macrophage #Immunometabolism Opinions are my own.

North Carolina, USA

Joined January 2021

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Michael Fessler, MD

@FesslerMd

1 year

RT @AJRCMB: 📣 CALL FOR PAPERS-Climate Change. Showcasing papers that investigate the mechanisms by which environmental climate change-relat….

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Michael Fessler, MD

@FesslerMd

1 year

RT @jclinicalinvest: #ResearchLetter: .Sterol biosynthesis regulates TLR signaling and the innate immune response in a Smith-Lemli-Opitz sy….

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Michael Fessler, MD

@FesslerMd

2 years

RT @AJRCMB: 📣 CALL FOR PAPERS-From Multi-Omics to Mechanisms of Lung Disease 📣 . Focusing on the use and impact of multiple omics technolog….

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Michael Fessler, MD

@FesslerMd

2 years

RT @AJRCMB: Meta-Analysis of COVID-19 BAL Single-Cell RNA Sequencing Reveals Alveolar Epithelial Transitions and Unique Alveolar Epithelial….

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Michael Fessler, MD

@FesslerMd

2 years

RT @AJRCMB: Endogenous and Therapeutic 25-Hydroxycholesterols May Worsen Early SARS-CoV-2 Pathogenesis in Mice. 🔓 Open Access.🔗 https://t.c….

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Michael Fessler, MD

@FesslerMd

2 years

RT @Lo_Zanzi: #WeekendRead! #InterferonPower ! Fessler &co show ⁦@jclinicalinvest⁩ that IRGM1 prevents excessive type I #IFN production & m….

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Michael Fessler, MD

@FesslerMd

2 years

RT @AJRCMB: Meta-Analysis of COVID-19 BAL Single-Cell RNA Sequencing Reveals Alveolar Epithelial Transitions and Unique Alveolar Epithelial….

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Michael Fessler, MD

@FesslerMd

2 years

IF staining of patient lungs confirmed the AT1 cell state. Interesting implications for unexpected repair pathways in lung and perhaps for diagnosis and therapy. @AJRCMB.

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Michael Fessler, MD

@FesslerMd

2 years

Peer harmonized public #COVID19 vs control BAL #scRNAseq datasets to detect rare cell states in the infected #lung. Among his many findings was evidence for aberrant alveolar epithelial type 1 cells with cornification and other signatures reminiscent of the skin!.

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Michael Fessler, MD

@FesslerMd

2 years

Our latest paper, led by talented Peer Karmaus with help from @Tatalab_Duke @TataAleksandra and other collaborators:

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Michael Fessler, MD

@FesslerMd

2 years

RT @Tatalab_Duke: 1/7 Latest paper in @CellStemCell! Transitional cell states sculpt tissue topology during lung regeneration. This work wa….

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Michael Fessler, MD

@FesslerMd

2 years

RT @JeffRathmell: Check out the line-up for the Gordon Research Conference on Immunometabolism! Excited to co-lead this with @LynnHedrickAU….

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Michael Fessler, MD

@FesslerMd

2 years

This counters the longstanding paradigm of IRGM1 as an #interferongamma cell-autonomous antimicrobial protein. Exciting implications. Thanks to our collaborators @mayer_barber and Greg Taylor.

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Michael Fessler, MD

@FesslerMd

2 years

Pleased to announce the latest work of talented Prashant Rai @mitoimunfection just published in @jclinicalinvest : We show that IRGM1 supports #hostdefense against intracellular #bacteria by suppression of type I #interferons!.

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Michael Fessler, MD

@FesslerMd

2 years

RT @mitoimunfection: Our latest brief report: type i interferon is the key factor that drives susceptibility to intracellular bacterial in….

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Michael Fessler, MD

@FesslerMd

2 years

RT @TeminiAjayiMD: Our study ⬇️. Race specific association of IRGM risk allele (implicated in Crohns and other diseases), with increased cy….

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Michael Fessler, MD

@FesslerMd

2 years

Exciting Senior Clinician opportunity at @NIEHS /NIH. Looking for physician scientist interested in grant-free, well-supported research leadership role. Apply on from 6/26–7/5 under “Supervisory Physician (Clinical)” in Durham, NC:

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Michael Fessler, MD

@FesslerMd

2 years

RT @Prof_Riggins: No #ENDO2023 live-tweeting for me this morning. because I'm chairing SY032, Orphan Nuclear Receptors at the Crossroads o….

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Michael Fessler, MD

@FesslerMd

2 years

Approaching the final week to apply for our Tenure-Track Investigator vacancy at intramural NIEHS/NIH!!.

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Michael Fessler, MD

@FesslerMd

2 years

RT @the_asci: ASCI member Michael B. Fessler @FesslerMd @NIEHS in @JCI_insight: 25-Hydroxycholesterol exacerbates vascular leak during acut….

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