Florian Scherer MD
@FSchererMD
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Clinician Scientist @Uniklinik_Fr. Hematologist/Oncologist. #Lymphoma #LiquidBiopsy #ctDNA ≠ medical advice
Joined April 2020
🚨Just out @CCR_AACR 🚨 V proud of our manuscript on polatuzumab efficacy by cell of origin in DLBCL We show COO by Hans predicts pola sensitivity in 740 pts Pts w R/R non-GCB DLBCL have higher ORR, CRR & PFS Massive thanks @dgermain21 & collabs! https://t.co/kGyRneMAuo
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📣#ESHCLL2026: PRELIMINARY SCIENTIFIC PROGRAMME NOW LIVE! ➡️ https://t.co/yyuD5rfxm7 4th Translational Research Conference on Chronic Lymphocytic Leukaemia March 5–7, 2026 / Stockholm, Sweden Chairs : Jennifer Brown Paolo Ghia, @HallekMichael
#ESHCONFERENCES #CLLsm #Lmsm
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Grateful to be here in lovely Freiburg, Germany for the 5th International Liquid Biopsy Symposium, organized by my good friend @FSchererMD at the University of Freiberg! @max_diehn will be giving the Keynote. I’ll be presenting our work on urine cell-free nucleic acids tmrw.
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Remission Assessment by Circulating Tumor DNA in Large B-cell Lymphoma | Journal of Clinical Oncology https://t.co/jmQh4QsR3n Read this paper which shows that ctDNA MRD by PhasED-Seq is the most precise way to define a remission after therapy for LBCL.
ascopubs.org
PURPOSELarge B-cell lymphomas (LBCLs) are curable, but patients with residual disease after therapy invariably experience progression. Ultrasensitive methods to detect circulating tumor DNA (ctDNA)...
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Glofitamab Combined With Pola-R-CHP or R-CHOP as First Therapy in Younger Patients With High-Risk Large B-Cell Lymphoma: Results From the COALITION Study | Journal of Clinical Oncology
ascopubs.org
PURPOSEImproved outcomes are needed for patients with high-risk (HR) large B-cell lymphoma (LBCL) who have <50% chance of cure with first-line (1L) R-CHOP chemotherapy. Patients with high burden or...
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🎯 Time to register for the 5th International Liquid Biopsy Symposium in Freiburg, Germany — Sept 19–20, 2025! 🌍 Join us on-site or virtually 🧬 Amazing lineup of speakers 📢 Abstract submission now open! 🔗 Register:
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Our very own CMO and co-founder, David Kurtz, was featured on the #ASCODailyNews discussing the incorporation of #ctDNA-MRD in NCCN Guidelines for B-cell Lymphoma. Read the article here: https://t.co/FeVsaschUR
#PrecisionMedicine #ctDNA #Diagnostics #MRD @ASCO
dailynews.ascopubs.org
Approximately one-third of patients with diffuse large B-cell lymphoma experience relapsed or refractory disease after first-line R-CHOP. Circulating tumor DNA/minimal residual disease testing can...
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We are very thankful for the great collaborations and support of all co-authors including @JurikMutter @StefanAlig @max_diehn @AshAlizadeh @LizSchorb and the support by @EKFStiftung @dfg_public @CRIIONorg @dgimev @DKTK_ @JCLStiftung
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Super happy to share our paper just published in @LeukemiaJnl, in which we demonstrate that minimal-invasive CNS lymphoma identification by ctDNA profiling in CSF can guide treatment and surgical management in daily clinical practice and large patient cohorts.
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Die #EKFS Publikationspreise 2024 gehen an: 🔹Prof. Dr. Frederik Damm 🔹PD Dr. Florian Scherer (@FSchererMD) 🔹Dr. Ria Schönauer 🔹Dr. Dr. Lukas Bunse (@L_Bunse) 🔹PD Dr. Roman Sankowski (@r_sankowski) https://t.co/r0P1SUNI5d
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Please RT and register: West German Lymphoma Symposium @HamatologieUk @UniklinikEssen @MedEssen @unidue @dgho_eV #sfb1530
lymphoma-symposium.de
-Thank you very much for your participation- Welcome Dear Colleagues and Friends Following the inaugural West German Lymphoma Symposium in 2024, we are delighted to continue this exciting new...
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Parallel to a great poster presentation by Dr. Miriam Mozaffari at #ASH2023, our new study was published in @BloodCancerJnl: Long-term follow-up of patients with acute myeloid leukemia undergoing allogeneic hematopoietic stem cell transplantation after primary induction failure
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The study was supported by @EKFStiftung, @dfg_public, @CRIIONorg, @Krebshilfe_Bonn, @dgimev, Foerdergesellschaft Forschung Tumorbiologie Freiburg.
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Very thankful for the great collaboration between Dept. of Stereotactic Neurosurgery, Neuroradiology, Radiology, and Hem/Onc @Uniklinik_Fr (esp. E. Lauer and P. Reinacher) and with co-authors incl. @AshAlizadeh @LizSchorb, @StefanAlig, @JurikMutter, @GeraldIllerhaus, @max_diehn.
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Finally, we leveraged 3D MRI volumetry and ctDNA detection (PhasED-Seq) to build a composite metric for outcome prediction at the earliest possible time point at diagnosis, which allowed the identification of patients with particularly favorable and unfavorable PFS and OS.
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We found that patients showing a >97% 3D tumor volume reduction in the first interim MRI (= 3D early response, 3D_ER) had significantly favorable outcomes compared to those who did not achieve 3D_ER, both in log-rank and multivariate regression analyses.
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