Frederick Peng, MD, FACP, DABOM
@FPengMD
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Gastroenterologist & obesity medicine physician. Trained at @bcm_gihep, @BCM_InternalMed, @TJUHospital. Views are my own.
Houston, TX
Joined June 2019
Obesity is a chronic, relapsing disease, and effective medication use requires high-quality, evidence-based care. Our new quality indicators define best practices. Read more here: https://t.co/BC2GbdlVlr
@AGA_Gastro @CNewberryMD @FPengMD @JenniferKMaratt
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📚 Functional GI Disorders – High-Yield Pearls (Dr. Rawan Dayah) 🧠 Hirschsprung Disease •❌ Absent RAIR (Rectoanal Inhibitory Reflex) → 🔍 Suggests Hirschsprung 🚽 Constipation •🌀 Colonic Inertia → ❌ No HAPCs (High-Amplitude Propagating Contractions) on manometry •🎈
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ACG guidelines on atrophic gastritis and gastric intestinal metaplasia 💡
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🚨 Big milestone in MASLD/MASH! We now have two FDA-approved drugs: 🔸 Resmetirom (oral, THR-β agonist) 🔹 Semaglutide (weekly SC, GLP-1 RA) I made this simple side-by-side comparison 👇
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Who better to kick off the Esophagus / Potpourri section than the motility maestro @WalterChanMD discussing “Updates in Management of EOE” 🔹 PPI therapy in EoE - BID dosing > QD for histologic response - 10–12 weeks improves remission rates - Approx 68% maintain remission on
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When we say GI is a small world, having the opportunity to invite #AhnNguyen my co-fellow from @UTSWGastroHep 📊 Acid control (Day 7 pH ≥4 time): •Vonoprazan: 85–94% •Esomeprazole: 61% •Rabeprazole: 65% •Lansoprazole: 42% ➡️ PCABs deliver faster, more potent acid
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Proud to share the new @C5NYC PSA on colorectal cancer screening in Mandarin Chinese: https://t.co/KjUZkcLAl0 Hope this is will help our Chinese-speaking patients get screened! @nyulangone @MSKCancerCenter @AmCollegeGastro @AmerGastroAssn @ASGEendoscopy
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A must-read review in the @NEJM on the most common cause of chronic liver disease: MASLD. All you need to know: trends, pathogenesis, early detection, co-morbidities, lifestyle changes and novel and future drugs….. https://t.co/epAuzLl6E7
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🔑ACG 2025 Preventive Care in IBD.Key Points: ✅ Vaccinations: - PCV20 or PCV21 instead of older schedules - Shingrix (2-dose recombinant) for all ≥50 yrs and ≥19 yrs if on immunosuppression - RSV vaccine for all ≥75 yrs & for 50–74 yrs w additional chronic conditions -
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🚨 New Data on Risankizumab in Crohn’s Disease! Even initial nonresponders to IV induction saw benefits with extended treatment 💉 📈 At Week 24: ✅ Clinical Response: – 76% (180 mg SC) – 64% (360 mg SC) – 62% (1200 mg IV) ✅ Clinical Remission: Up to 45% ✅ Endoscopic
cghjournal.org
The efficacy and safety of extended treatment with risankizumab (RZB), an anti-interleukin-23 p19 monoclonal antibody, were evaluated in patients with moderate to severe Crohn’s disease (CD) who did...
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Forever grateful to @bcm_gihep for giving me the unique opportunity to train at a world-class institution and meet incredible mentors, peers, and people along the way. Proud to be a part of the first graduating class under PD @milenasuarez and looking forward to the future!
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Summary of REDEFINE 1 and REDEFINE 2 trials with CagriSema, presented this week at #ADA2025 and published in NEJM: REDEFINE 1: • 👥 3,417 participants with obesity or overweight (without diabetes) treated with CagriSema achieved a 22.7% weight loss after 68 weeks, compared to
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Evaluation of Symptoms Suspicious for GERD - Value of Endoscopy ⭐️Assess integrity of EGJ ⭐️ Several pitfalls of Hill classification! Consider using 🆕 AFS Endoscopic Classification of the Esophagogastric Junction Integrity! 🔗 https://t.co/5elerYsX6F 🙏Dr Gyawali #EBMed
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GLP-1RAs were associated with an increased risk of GERD and cholelithiasis but did not significantly increase the risk of pancreatitis, cholecystitis, intestinal obstruction, or other serious gastrointestinal or biliary events. GLP-1 RAs were associated with increased the risk
gastrojournal.org
Glucagon-like peptide-1 receptor agonists increase the risk of gallstones and acid reflux, but not other gastrointestinal or biliary-related complications.
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🚨 New ACG Crohn’s Guidelines (2025) ▪️Scope at 6–12 mo post-op ▪️Early advanced therapy = key ▪️Anti-TNF, IL-23, JAKi > mesalamine ▪️High-risk = smoking, prior surgery, penetrating dz ▪️Surgery for abscess >2cm or strictures 🔗 https://t.co/PfEj2Rvnke
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📣#DrCynthiaYoshida taking the mystery out of abdominal pressure during colonoscopy @AmCollegeGastro #EndoscopySchool 👉🏻Right Place 👉🏻Right Time
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There are 3 methods to stop diverticular bleeding - indirect vs direct clipping, or banding. While direct clipping is suggested to be superior, it’s hard! If bleeding is in L colon, I perform band ligation. Ask for it pre-installed on another scope to save time.
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🔍 Managing Fibrotic Strictures in Crohn’s Disease: What Are the Options? 1️⃣ Endoscopic Dilation ✅ First-line for short (<5 cm), uncomplicated strictures 💥 70–80% short-term relief 🔁 30–60% recurrence within 5 years ⚠️ Low complication rate (3–5%) ➡️ Ideal to delay surgery
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What is palliative care for #cirrhosis? 1. A strategy to support patients 2. Interventions proven to relieve symptoms 3. Tools proven to guide decisions 4. Complements the goals of transplant palliative care is not a referral. It is a strategy. A way of caring
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