Sandra Encalada Lab
@EncaladaLab
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Our lab studies the cell biology of neurons, in health and disease. Actively fighting neurodegeneration with science. Opinions my own.
La Jolla, CA
Joined November 2018
Don't miss out! Join us for an amazing lineup at the 30th year anniversary FASEB Protein Aggregation Conference, Scottsdale AZ, June 28-July 2, 2025 Submit your abstracts by May 16, with@SaelicesL@fauxLukasz
https://t.co/unIDEkpW5G…
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So glad to be invited to speak at the FASEB Protein Aggregation: Polymorphic Species conference - a real privilege to be among such thoughtful voices. Thank you for having me and I am looking forward to the conversations. https://t.co/jXDWWOD8jJ
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Excited to co-organize the 2025 FASEB Protein Aggregation meeting in Scottsdale AZ, June 28-July 2, 2025 with @SaelicesL @fauxLukasz. 30th year anniversary special edition! Submit your abstracts for a talk or poster by May 16. Apply for a travel award! https://t.co/unIDEkqtVe
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I am co-chairing the 2025 FASEB Protein Aggregation Conf (June 28–July 3, Scottsdale AZ)! 🎉 It is the 30th anniversary! Keynote talk by Jeffery Kelly! Early registration ends 5/17. Travel awards available! Join us! https://t.co/hnLGwNCD7s
#amyloids #proteinaggregation
@FASEBorg
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Excited to participate in this event. Join me in NYC! Therapeutic Approaches to Protein Misfolding In Neurodegenerative Disease
events.nyas.org
Join me for this event: Therapeutic Approaches to Protein Misfolding In Neurodegenerative Disease
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This is as good a time/way as any to spread the word: I have *multiple* positions open to study cochlear hair cells in my lab! We have all the toys you'd ever want for these studies and an amazing group of computational, cell biology, and hearing experts all working together.
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🇪🇨 Piero Hincapié brilló en el triunfo 3-1 de Ecuador ante Jamaica, siendo clave tanto en defensa como en ataque. Su remate desde la izquierda abrió el marcador y fue celebrado por todos los ecuatorianos como su gol. ¡Vamos, Tri! #CopaAmérica #Ecuador 👇 https://t.co/C33KcEIrkC
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Wanna work towards finding a treatment for prion diseases and Alzheimer's disease? #AlzheimersDisease #curepriondiseasescripps Join us! Awesome postdoc fellowship opportunity @scrippsresearch in pretty awesome San Diego:
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Picture time 👨🎓It’s truly a privilege to have Sandra as my mentor throughout my time at Scripps. Thank you for the continuous support and I can’t wait to collaborate on more exciting science! 🥳
Congratulations to Tai Chaiamarit @BioTai1 who graduated yesterday with 2 degrees! from @scrippsresearch and Oxford University, and now has started his own independent lab as faculty at Mahidol University. Brilliancy all around, congratulations Tai, so proud of you!
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Congratulations to Tai Chaiamarit @BioTai1 who graduated yesterday with 2 degrees! from @scrippsresearch and Oxford University, and now has started his own independent lab as faculty at Mahidol University. Brilliancy all around, congratulations Tai, so proud of you!
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One of the craziest things I learned last week at #AAI2024 was that we have more free-floating extracellular mitochondria in our blood than white blood cells. This was not in any textbook that I ever read! https://t.co/wT3mQtZDyj And the original paper: https://t.co/9NNSVaGMrn
sci.news
Researchers have demonstrated that human blood contains whole functional mitochondria in normal physiological state.
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Astrophysicist and Nobel laureate Subrahmanyan Chandrasekhar used to travel 80 kilometers every week from the Yerkes Observatory to the University of Chicago, where he taught a course attended by only two students. When asked why he spent his time this way, the professor replied
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Now a faculty member at @MahidolU, @EncaladaLab doctoral student and 2024 graduate @BioTai1 investigated the identity and biogenesis pathway of mutant #prion protein aggregates in axons by live and quantitative microscopy approaches. Learn more at: https://t.co/fM0dsLsRk1
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Very proud PI
In the @LippiLab, Norjin Zolboot developed molecular tools for manipulating #microRNAs and their #mRNA targets w/vastly improved spatial & temporal resolution, and discovered novel #microRNA roles underlying cerebellar Purkinje cell development. Read more: https://t.co/fM0dsLsRk1
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A fully integrated collaboration between biologists and chemists reveals a compelling approach to prevent tau aggregation in 4R tauopathies
pnas.org
Prion-like spread of disease-specific tau conformers is a hallmark of all tauopathies. A 19-residue probe peptide containing a P301L mutation and s...
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Join us! A Postdoctoral Fellowship position is available in the Encalada Lab at Scripps Research in La Jolla, California, USA, in the areas of neurodegeneration, aging, and intracellular endolysosomal trafficking @EncaladaLab; @scrippsresearch:
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Looking forward to speaking at ASCB’s upcoming virtual meeting, “Emerging Concepts: Structural Cell Biology in the Nervous System”. In situ architecture of mutant prion protein aggregates with @manorlaboratory
https://t.co/DiBQ1ppW2b
#CellBiology #CellScience
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My oped on the JN.1 variant and the 2nd biggest US wave of infections (after Omicron) since the pandemic began https://t.co/lcjc3meV1n
@latimes @latimesopinion #LongCovid
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My first-author paper looking into how copper and oxidation modulate #prion protein #phaseseparation is out🤩 Thank you for all support from fantastic PhD mentors and collaborators! @yraima_cordeiro @WegmannLab @Msatabdee @alinerpassos
https://t.co/lz1EodDLXA
science.org
Copper-induced prion protein condensation transitions into aberrant protein aggregation in oxidative condition.
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@EncaladaLab had a great visit to Scripps. It was great to see some old friends and make some new ones. Thanks Sandra for being such an amazing host! Although it was a fantastic trip, Enzo was pleased to have me home.
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