Emmy Li
@EmmyLiTweets
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Graduate Student @KampmannLab. Fan of ocean creatures and some land creatures.
San Francisco, CA
Joined December 2008
It’s alive on BioRxiv! Super excited to present our paper on CRISPRi-based screens in 3D neuron-astrocyte-microglia co-culture (iAssembloids) to examine neuron-glia interactions. Description of this work in the thread below! Too many words! (1/8) https://t.co/tszpNqFWQJ
biorxiv.org
The sheer complexity of the brain has complicated our ability to understand its cellular mechanisms in health and disease. Genome-wide association studies have uncovered genetic variants associated...
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Yay! Great work Xinyi!
Thrilled to share our preprint led by @chenxinyi924 on programmable molecule delivery via engineered trogocytosis called TRANSFER! a 🧵 @Stanford_ChEMH @bioe_stanford
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Astrocyte friends: I’m in need of advice. I’m looking for a good astrocyte antibody and a tamoxifen-Inducible Cre driver line for hippocampal astrocytes. What would you recommend?
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Congrats Steven et al!!!! So excited to see this on the archives!
Have you ever wanted to profile how a molecular pathway affects neuronal activity, but didn't know where to start? I'm excited to share "A Massively Parallel CRISPR-Based Screening Platform for Modifiers of Neuronal Activity" 1/
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Have you ever wanted to profile how a molecular pathway affects neuronal activity, but didn't know where to start? I'm excited to share "A Massively Parallel CRISPR-Based Screening Platform for Modifiers of Neuronal Activity" 1/
biorxiv.org
Understanding the complex interplay between gene expression and neuronal activity is crucial for unraveling the molecular mechanisms underlying cognitive function and neurological disorders. In this...
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Congrats Nawei and Noam for conducting the largest CRISPR-based screen of high confidence autism risk genes conducted to date. Follow the link for more details! @snw555 @noamteyssier @belinda_p_wang @fimazaltsman @MartinUCSF @UCSF @Spectrum @SFARIorg
https://t.co/Hp8hCkTsb9
linkedin.com
Super proud of Nawei S. and Noam Teyssier for their tireless work in producing this fantastic manuscript, which systematically characterizes the cellular and molecular consequences of disrupting...
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Very excited to present our recent preprint! This was a massive effort over the past three years that investigates the complex biology of high-confidence ASD (hcASD) genes during early timestamps of neurogenesis using single-cell CRISPRi. https://t.co/juHC9hE4rx
biorxiv.org
Recent studies have identified over one hundred high-confidence (hc) autism spectrum disorder (ASD) genes. Systems biological and functional analyses on smaller subsets of these genes have consiste...
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I need to fax something and this gives me 5 free pages What the fax?! I guess faxing isn’t dead 🤷♂️ Use Dropbox Fax by @DropboxSign to send and receive faxes from anywhere. #DropboxFax
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Very excited to share our latest @vram142 lab preprint on developing methods for long-read footprinting of protein-DNA contacts in newly replicated chromatin fibers, co-led with Megan Ostrowski. https://t.co/TJjBfJzCgF (1/x)
biorxiv.org
The higher-order structure of newly replicated ( i.e. ‘nascent’) chromatin fibers remains poorly-resolved, limiting our understanding of how epigenomes are maintained across cell divisions. To...
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Don't miss Dr. Avi Samelson's talk today on "Protein folding and misfolding in context: from the ribosome to neurodegeneration"! HSEB 2680 at 4pm.
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Love seeing our review featured on the cover! Move over astrocytes and microglia, there’s a new kid on the block #opcs @JoJoBuchanan1 @CSHL @AllenInstitute
Check out the August 2023 issue of @TrendsNeuro: https://t.co/k6qoYUOZx4 On the cover: 'Emerging roles of oligodendrocyte precursor cells in neural circuit development and remodeling' by JoAnn Buchanan @JoJoBuchanan1, Nuno da Costa & @LucasCheadle
https://t.co/j6bYCjcwXL
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Abstract submission is open for the Neurobiology of Aging GRS ( https://t.co/FMFMIv9BCc). We would love to see a diverse group of trainees represented in Spain next summer to discuss mechanisms of neurodegenerative disease!
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Have you seen this publication from the @AkassoglouLab? Shoutout to the collaborators and funders: @andrewmendiola
@xanderpico
@KroganLab
@UCSF
@QBI_UCSF
@NIH
@NIHAging
@NINDSnews
@mssociety
@_BrightFocus
https://t.co/jotB81ERxW
nature.com
Nature Immunology - Akassoglou and colleagues provide a single-cell RNA sequencing and phosphoprotein analysis of the responses of central nervous system microglia and macrophages to blood proteins...
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🥳🥳🥳
So excited to be part of this adventure!
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🚨New Peer Reveiw: "CRISPRi-based screens in iAssembloids to elucidate neuron-glia interactions" @EmmyLiTweets 📝 Reviewed by @jeffyfish9 (🏦@UCRiverside.) Read it here👉 https://t.co/wYoBid31XT
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Yay awesome job guys! So proud of the work you’ve done
Our intrepid interns @joannachou0221 and Anjani are showcasing their awesome works! Come to Genentech Hall from 11AM - 2PM at @UCSF to ask them about CRISPRi based functional genomics! @CCSFBiotech @OfficialCCSF
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Congrats @LucasCheadle! So well deserved! 🍾🎊🎉
Incredibly excited to share that I will be joining the #HHMINEWS family as a Freeman Hrabowski Scholar. This award will fund our work on neuroimmunological mechanisms of brain development and function over the next 5 - 10 years.
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Of course, last but not least, none of this study would be possible without the support of my awesome mentor @MartinUCSF who makes our work possible and the @KampmannLab such a fun place to do science! (8/8)
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A BIG THANK YOU TO my friends and colleagues who not only supported several aspects of this study but also have been one of the best parts of my PhD experience: @itsmecamib, @ChemBioBoggess, @MarkKoontz5, @IVLRose, @DraegerNina, @OMTeter, @asamelson1, @UllianErik (7/8)
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Our platform expands the toolbox indeed, To understand the brain’s cell-cell feed, With iAssembloids and CRISPRi, We’ll uncover mechanisms in reply And in scientific progress, we will proceed. (6/8)
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