Emil Kristoffersen
@EmilLK2
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Related to the Origin of Life No longer active on X, find me on Bluesky.
Joined April 2016
We have submitted our second paper on the topic the RNA world in collaboration with @PhilHolliger based on experimental work by @EmilLK2 and @mcrae_ewan in the @AndersenBioLab. Preprint is available on bioRxiv! Here comes a short explanation of the background and content.đ§”1/7:
Roles of dimeric intermediates in RNA-catalyzed rolling circle synthesis https://t.co/Kbp0DCTYBO
#biorxiv_biochem
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New preprint from my lab, based on a great collaboration with @esandersen and @mcrae_ewan, @EmilLK2.
Roles of dimeric intermediates in RNA-catalyzed rolling circle synthesis https://t.co/Kbp0DCTYBO
#biorxiv_biochem
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Read our latest story on the circles of life đ
Nice news story about our recent research into the mythical RNA world, where we have explored the structure of the (proposed) central player: the RNA replicase. Thanks to @EmilLK2, @mcrae_ewan, @PhilHolliger and coauthors for making the research possible.
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4-year studentship available in my lab at @kclchemistry working at the interface of fundamental synthetic biology and therapeutic biotechnology development - come & join me in the XNA world! Please RT https://t.co/wFpGZlRQ23
findaphd.com
PhD Project - Chemical evolution of artificial oligonucleotide catalysts for ultra-specific RNA detection and knockdown at Kingâs College London, listed on FindAPhD.com
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Nice news story about our recent research into the mythical RNA world, where we have explored the structure of the (proposed) central player: the RNA replicase. Thanks to @EmilLK2, @mcrae_ewan, @PhilHolliger and coauthors for making the research possible.
sciencenews.dk
Life on Earth is likely to have arisen by an RNA molecule that started to make copies of itself. RNA researchers have succeeded in recreating an RNA copy machine and determining its structure...
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Outreach talk at the Danish Science Festival in April: âOrigin of Life in an RNA Worldâ https://t.co/aIUCIqv8YK
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Our cryo-EM structure of an RNA polymerase ribozyme is now available in the databank with the PDB ID 8T2P: https://t.co/8EIWKc4F17
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CryoEM unveils structure of nano-sized 'RNA copy machine,' a key player in the ancient RNA world. This breakthrough may fuel RNA nanotech and medical advancements. 𧏠@esandersen, @PhilHolliger, and @mcrae_ewan et al. publish findings in PNAS (@PNASNews). https://t.co/HdKtBI90Es
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Never expected to see this: #RNA on the (reverse) cover of the journal Proteins! Congrats to @RachaelKretsch and all authors of the #CASP15 special issue!
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The emergence of #life on Earth: LMU is launching the new Collaborative Research Centre TRR 392 âMolecular #Evolution in Prebiotic Environmentsâ, funded by @dfg and founded on the research of @emergenceoflife. https://t.co/1NY7hzSfuE
lmu.de
The interdisciplinary project will investigate how the first evolution of molecules began.
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Det har faglige konsekvenser, nÄr man reducerer uddannelser fra 2 til 1 Är. Det skal #dkpol vide, nÄr man laver sÄ gennemgribende indgreb pÄ #DKuni, som @regeringDK lÊgger op til. @kristian_lauta med vigtige input til @folketinget's Uddannelses- og Forskningsudvalg. #uddpol
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New content online: Structure, folding and flexibility of co-transcriptional RNA origami https://t.co/sRbKHK3j4S
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Check out the new results from @esandersen's group at @iNANO_AarhusUni and @MolBiolAU at @AarhusUni_int and colleagues from @BerkeleyLab
Nanosatellite leads researchers from @AarhusUni and @BerkeleyLab to the discovery of a helpful trap in #RNA folding, which may further pave the way to RNA medicine of the future. Publ. in @NatureNano
#RNAorigami #Nanomedicine #nanotechnology #CryoEM
https://t.co/evaRmRZdsT
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BREAKING NEWS: The Royal Swedish Academy of Sciences has decided to award the 2022 #NobelPrize in Chemistry to Carolyn R. Bertozzi, Morten Meldal and K. Barry Sharpless âfor the development of click chemistry and bioorthogonal chemistry.â
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Happy to share our preprint based on an exciting collaboration with @PhilHolliger. Thanks to the team for making it happen: @mcrae_ewan, @ChrisJWan, @EmilLK2, Kalinka Hansen, @edo_gia, @isaac_sur, @joe_curran1 and @DrJamesAttwater.
biorxiv.org
The emergence of an RNA molecule capable of replicating itself and other RNA sequences is a central pillar of hypotheses regarding the origin of life[1][1],[2][2]. In vitro evolution has yielded...
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I was very pleased when @EmilLK2 and @PhilHolliger approached me, wanting to know the structure of RNA mincircles as they undertake rolling circle amplification. Here is the result of our simulations, now published in @eLife :
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We are looking for a postdoc at the MRC Laboratory of Molecular Biology, Cambridge, UK: https://t.co/9dnyS2ESdz. Candidates should have a strong background in molecular biology and technology development, ideally including in vitro evolution and machine learning. Please RT!
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New paper from my group "Rollling circle synthesis catalyzed by RNA": https://t.co/LZiAeHeuzp. Led by https://t.co/vQpbUndv4j and a great collaboration with https://t.co/MzPX7CdfZ2 in York. We show that RNA alone can catalyze all the steps of a viroid-like replication cycle.
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