CrozrX
@CrozrX
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"In recent years, we have witnessed remarkable progress in targeting KRAS through small molecule inhibitors. In addition to the clinical success of KRASG12C inhibitors, we are experiencing a renaissance in RAS-targeted therapeutics. The field is advancing on multiple fronts:
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Jorge L. Borges wrote that every writer creates his own precursors. A truly original work does not join history, it rearranges history so that every prior discovery now looks like it existed only to announce its coming. Verastem Oncology wasn’t just named with “RAS” hidden
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⚽️ 🏆 🌎 🇺🇸 🇭🇷 🇪🇸 🇧🇷
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I am proud to announce the official opening of the UPMC Hillman Center - Croatia, marking a historic step in cooperation between the USA and Croatia.
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AI-Powered Revolution: Ushering in the TRUE Precision Medicine Era in Oncology! Just unpacked this pivotal review in Cancers : "Advances in Precision Oncology: From Molecular Profiling to Regulatory-Approved Targeted Therapies" by Brlek et al. Dragan Primorac 🇭🇷 🇺🇸 We’re no
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JOINT PROGRAM UPDATE GenFleet Therapeutics / Verastem Oncology 🔸️ https://t.co/C5dJdpR0XF 🔸️ 🚀 RAPID PACE + TOLERABILITY PIVOT + CHINA-U.S. SYNERGY: GFH375/VS-7375 Sets the KRAS G12D Standard 1️⃣ Blistering Speed - FIH: 07/09/24 - Ph2 start: 02/2025 - US Phase 1/2a
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Amazing what little changes in protocol can do! 📍 In the precision medicine era, the commitment is to the patient, where thoughtful refinements, such as evaluating GI side effect mitigations including use of prophylactic anti-emetics, dosing with and without food, and
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Fantastic #KRAS G12D #esmo25 @myESMO GFH375 PDAC data! RAMP205 PDAC data with avutometinib and defactinib looks pretty awesome, as well! @VerastemOncolog should explore this triplet!! @OncoAlert
🚨 Gfh375 KRAS G12D PDAC #esmo25 abstract is out!🚨 1/ GFH375 in KRAS G12D PDAC (NCT0500676; Ph1/2; includes Ph1*; cutoff Aug 27, 2025): 🔸️66 pts at 600 mg QD, median exposure 117d (68% ≥2L). Evaluable (n=59): 🔸️ORR 41% (90% CI 30–52), 🔸️DCR 97% (90% CI 90–99).
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This is a fantastic and comprehensive review on cell free DNA fragmentomics in cancer. Out in @Cancer_Cell
https://t.co/4qR6IF1w8G
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The chessboard king, the most crucial yet vulnerable piece, symbolizes the intricate complexity of each cancer patient. In the realm of precision medicine, strategy embraces this complexity at the molecular level, while tactics transform breakthrough research into personalized
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Those that are fans of “The Seventh Seal” will be interested in this piece by physician-scientist, author and award-winning blogger Milton Packer: Is It Time to Play Chess With Death?
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Reflecting on the Human Struggle Against Cancer In a world where knowledge often shields us from the unknown, it’s profoundly humbling to witness the personal battles faced by individuals like @DRCamidge and beautiful piece written by dr. Milton Packer, a piece shared a few
One of the biggest influences on my career is Dr. Ross Camidge - a mentor and friend, an intellectual giant in the field of lung cancer who was diagnosed with this unforgiving disease himself. We are all at risk - and must all work to move the field. https://t.co/GHuaFBUoBm
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⚽️ 🇮🇹 🇭🇷
📽️ Luka Modrić's presentation at San Siro before the Coppa Italia match against Bari. https://t.co/4ycuFv3fY5
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