#IDTwitter How often are antimicrobials given in pediatric hematology/oncology, and how often is it appropriate? We conducted a multi-center point-prevalence study (PPS) in 🇩🇪 and 🇦🇹 What’s more, we checked EACH prescription for appropriateness   Here is what we found —> 1/11

#ESPID2025 #IDtwitter @ESPIDsociety New Vaccines in Town: Paratyphoid vaccine could become the first to be licensed on basis of controlled human infection model (CHIM) @AndrewPollard

We are delighted to announce the publication of UTI WikiGuideline in JAMA Network Open. Thank you to the 54 experts from 12 countries for drafting. Special thanks to @zacroBID and @amenalor for leading the effort. https://t.co/XC2MgtjTdb

A heartfelt thank you to the @PaulEhrlichGes for honouring our work with the Wolfgang Stille Award 🙏 here is the link to the paper: https://t.co/eAkz7nD7Xb @LancetRH_Europe

New Comment from Yael Lohse and colleagues: Migration background, skin colour, gender, and infectious disease presentation in clinical vignettes. Read it here:

#ESCMIDGlobal2024 David Resnik on why #AI #LLM such as ChatGPT do not qualify as authors of a publications —> lack of accountability —> lack of moral responsibility Among other arguments @ESCMID

#ESCMIDGlobal2024 Highly engaging talk and discussion on the potentials and perils of large language models #LLM in medicine @GermHunterMD Hall B @ESCMID #AI

Observed even a Decreased infection rate Intriguing findings given the not-so-bad baseline compliance rates already #ESCMIDGlobal2024

Multimodal intervention led to increased compliance in almost all hand hygiene moments

There are up to 30 opportunities for hand hygiene in one cycle of hemodialysis —> a lot of chances to decrease infection rates

Tobias Kramer from @ChariteBerlin reporting findings of their cluster-randomized trial on hand hygiene intervention in outpatient hemodialysis centers #ESCMIDGlobal2024 @ESCMID

#ESCMIDGlobal2024 Nicholas Grassly on the potential of wastewater surveillance for other pandemic-risk viruses, e.g. #Zika #Lassa Hall I

#ESCMIDGlobal2024 ESCMID Study Group for Antimicrobial Stewardship Business Meeting — the room is packed

tl;dr: - Although BV score differentiates well between bacterial and viral RTI —> use with caution in “atypical” pathogens like Mp - Although imperfect in Mp —> microbiological testing remains important - These findings come in time as Mp resurges —>

Finding #2: Combining clinical features (age, duration of fever, duration of resp. symptoms) with BV performed as well as combining them with PCT (AUC 0.86 vs. 0.87) in terms of discriminatory accuracy 6/n

Findings: - BV score was significantly lower in Mp+ CAP than in MP- CAP (median 14 vs. 54), looking more like a “viral” pneumonia - In line with this, TRAIL levels were higher and CRP lower in Mp+CAP than in Mp-CAP 5/n

Due to the “atypical” properties of Mp, we hypothesized that the score would yield a lower value in Mp+ community-acquired pneumonia (CAP) compared with Mp- CAP. 4/n

The BV score yields a numeric value from 0 to 100 with the following ranges and their interpretations: 0-34: indicating viral 35-65: equivocal 66-100: indicating bacterial See our work on its diagnostic accuracy in a large pediatric cohort: https://t.co/rt9CcIlrdp 3/n

First, some facts about Mp: - “Atypical” bacterium (e.g. lacks cell wall) - “Atypical” presentation - Hard to diagnose (serology is unreliable, PCR does not discriminate infection from carriage) - Almost disappeared during the Covid pandemic, but seems to be resurrecting! 2/n

#IDTwitter 📢Just published🔥 The BV score (TRAIL + IP10 + CRP) discriminates quite well between bacterial and viral respiratory tract infections (RTI). But how does it perform in #pneumonia caused by Mycoplasma pneumoniae (Mp)? https://t.co/855FfcMnZm 1/n

Automation as the future of surveillance in infection prevention and control - not a question "if" but rather "how" - splendidly showcased by @mo_abbas_ipc at #ECCMID2023 #ECCMID23