Cahova Group of Chemical Biology
@CahovaB
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Chemical biology lab @IOCBPrague focusing on RNA modifications.
Prague
Joined January 2019
RT @IOCBPrague: PhD Positions at IOCB Prague – Call for Applications 2025. Explore 20+ projects in #OrganicChemistry #Biochemistry #CellBio….
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Huge congratulations to @tomas_pluskal!!!.
27 life scientists have been selected as the newest members of the EMBO Young Investigator Programme. Congratulations and welcome!.Read more:.
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Congratulations to Flaminia Mancini on her detailed review of methods currently available for the detection of non-canonical RNA caps! #RNA #Epitranscriptomics @rna4t_opjak Thanks #ChemBioChem for the opportunity.
#ChemBioChem The Mysterious World of Non-Canonical Caps----What We Know and Why We Need New Sequencing Techniques (Hana Cahova and co-workers) @CahovaB @IOCBPrague #openaccess
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Back in Heidelberg for The complex life of RNA! #EESRNA If you want to know more about non-canonical RNA capping, stop by the posters of our two postdocs Ondrej (206) and Pavel (068)! #NAD #Ap4A #epitranscriptomics @EMBLEvents
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Good news! Our Ap4A-RNA paper received over 2,000 views since its publication! Stay tuned for more non-canonical RNA cap research. #ViewsMilestone #RNA #Ap4A #Epitranscriptomics @rna4t_opjak.
onlinelibrary.wiley.com
Diadenosine tetraphosphate-RNA (Ap4A-RNA) is found in human and rat cell lines. Its amount is not dependent on the intracellular concentration of Ap4A. Ap4A-RNA is decapped by two enzymes, NUDT2 and...
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Two of our members also attended the @ItsRMaP1 conference on RNA modifications @imbmainz last week. Thank you to the organizers @AttheHelm3 and @koenig_lab for an amazing event! And congratulation to @Potuza for winning the @embojournal poster prize!!! #RNA #AP4A @rna4t_opjak
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We've had a busy past few days in our group. We all attended the RNA Club 2024 @CEITEC_Brno and the @rna4t_opjak kickoff. Thank you to the organizers and a big congratulations to @BiancaMariaMit2 for winning the best talk prize!!! #RNA #epitranscriptomics #Ap4A
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@BiancaMariaMit2 @IOCBPrague @CharlesUniPRG @rna4t_opjak @science_charles Also a big thank you to the committee for their inspiring questions - we will certainly try some of the ideas out.
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A new PhD is among us! Congratulations to @BiancaMariaMit2 on her successful thesis defense and thanks for all your hard work and time spent in our lab. We will miss you! Stay tuned for Bianca's paper about a novel RNA cap. @IOCBPrague @CharlesUniPRG @rna4t_opjak
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We are looking for a talented postdoc to join our #ERC and @rna4t_opjak funded lab @IOCBPrague . If you love #RNA, epitranscriptomics, and mass spectrometry, contact us!!!.
#openposition #chemicalbiology #postdoc. The #chembiol group of @CahovaB at @IOCBPrague is hiring a postdoctoral research associate in #cellbiology & #molecularbiology (1–5 years). The group studies non-canonical RNA capping and recently discovered that various metabolites serve
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We're delighted to welcome the newest member of Cahova group - Acquity Premier System with Xevo TQ Absolute from @WatersCorp. This machine is a beast, no RNA caps can hide from us now!!! #RNA #Ap4A #epitranscriptomics #LCMS #NAD @IOCBPrague @rna4t_opjak
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We wrote a review about non-canonical #RNA caps and all they do (or don't do). From methylated 5' phosphates to #Ap4A, #NAD, #FAD, #UDP-glucose and more. Thanks @WeAreTandF for the opportunity! @rna4t_opjak #RNAmodifications #epitranscriptomics.
www.tandfonline.com
RNA capping is a prominent RNA modification that influences RNA stability, metabolism, and function. While it was long limited to the study of the most abundant eukaryotic canonical m7G cap, the fi...
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Amazing conference last week! Thank you @AegeanConf and all the amazing #RNA scientists for such a wonderful time. Excited about all the new ideas and collaborations! Now it's time to get back to the lab. #NonCoding #RNAs #Chania #Crete #Kolymbari #Greece
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Check out the poster of our PhD student @BiancaMariaMit2 at the @AegeanConf 5th International Conference on the Long and the Short of #NonCoding #RNAs #Chania #Crete #Kolymbari #Greece.
Happy to present my poster at the 5th International Conference on the Long and the Short of #NonCoding #RNAs #Chania #Crete #Kolymbari #Greece June 17-22
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Our lab recently published a paper about the relationship between #HIV-1 infection and #NAD #RNA capping - congrats to all authors!!!.#RNAmodifications @rna4t_opjak @IOCBPrague @ACSPublications.
pubs.acs.org
Nicotinamide adenine dinucleotide (NAD) is a critical component of the cellular metabolism and also serves as an alternative 5′ cap on various RNAs. However, the function of the NAD RNA cap is still...
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Our new preprint is out on @biorxivpreprint! We use a combination of @nanopore and LC-MS to explore #RNAmodifications in viroids. A huge thanks to our collaborators @beatriznavarami and @Frances9000 for all their work!!! .#RNA #epitranscriptomics #m6A.
www.biorxiv.org
Viroids, small circular non-coding RNAs, act as infectious pathogens in higher plants, demonstrating high stability despite consisting solely of naked RNA. Their dependence of replication on host...
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We are proud to be part of this amazing project and in the company of such excellent scientists! #RNA #RNA4T.
🧬 The full potential of RNA technology remains unexplored since there are fewer than a dozen FDA-approved RNA therapeutics so far. #RNA4T, a project led by @hocekm @IOCBPrague and bringing together 14 research groups from IOCB Prague, @imgprague, @BiologyCentre, Inst. of
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RT @science_charles: 📢 Exciting Announcement! Join us at the "Let's Transfer Science" conference on Feb 6, 2024, Albertov 6. 🌐 Explore the….
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We are looking for a new motivated PhD student to join our @ERC_Research funded lab! If you love RNA and Prague (not necessarily in that order) and want to study at the @IOCBPrague, apply now!!!.#RNA #PhDposition.
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