After improving manufacturing efficiencies for local anesthetic Exparel, @PaciraBio is cutting 71 employees in San Diego, which is about 8% of its workforce. Learn more in our layoff tracker. #layoffs #biopharma #biospace.

In its complete response letter, the FDA cited insufficient evidence establish deramiocel’s effectiveness for cardiomyopathy associated with Duchenne muscular dystrophy. The decision comes after CBER Director Vinay Prasad canceled an advisory committee meeting for the therapy.

The approval of Moderna’s Spikevax for kids at higher risk of contracting the disease continues the company’s regulatory winning streak, which has also included nods for a next-gen COVID-19 vaccine and an RSV shot. #regulatory #biospace.

A journey through the FDA’s newly released complete response letters gave glimpses into the journeys to market for @EliLillyandCo's Alzheimer’s antibody Kisunla, Sarepta’s DMD gene therapy Vyondys 53 and Gilead’s HIV drug Sunlenca. #alzheimers #FDA #biospace.

The trove of more than 200 letters is part of a pledge of transparency from the agency, with the intention to increase public insight into the reasons new drug and biologics applications got rejected. #FDA #biospace.

The deal, which involves a $700 million upfront payment, gives @abbvie access to ISB 2001, a clinical-stage first-in-class trispecific antibody currently being tested for certain kinds of multiple myeloma as well as autoimmune indications. #pharma #biospace.

Partners Ultragenyx and Mereo BioPharma saw their stocks drop by 21% and 30%, respectively, after announcing that the Phase II/III study of their osteogenesis imperfecta candidate will proceed to final analysis, implying it did not show sufficiently strong results at an interim.

Century Therapeutics is laying off 51% of its employees in a bid to “right size” the company, according to a July 7 regulatory filing. Get the details in our layoff tracker. #layoffs #biopharma #biospace.

In this episode presented by Eclipsebio, BioSpace’s head of insights Lori Ellis discusses mRNA and srRNA with Andy Geall of Replicate Bioscience and Alliance for mRNA Medicines, and Pad Chivukula of Arcturus Therapeutics. #podcast #vaccines #biospace.

The number of employees laid off and companies letting people go increased year over year during the first half of 2025. We recap the five largest layoff rounds, including cuts at @Bayer, @bmsnews and @TevaUSA. #layoffs #biopharma #biospace.

The 2025 Genetown Hotbed is comprised of Boston, Cambridge and the surrounding areas of Massachusetts. Companies like Takeda, Moderna, Intellia Therapeutics and more are hiring now. Take a look at this region.

The move has sparked concern that the U.S. Preventive Services Task Force could soon be dismissed after a decision by the high court affirmed Health Secretary Robert F. Kennedy Jr.'s power to remove its members at will. #government #HHS #biospace.

The Global Fund to Fight AIDS, Tuberculosis and Malaria will work with @GileadSciences and other private backers to ensure the HIV preventive Yeztugo, approved last month by the FDA, is available in low- and middle-income countries, concurrent with high-income nations. #HIV #FDA.

Nuclidium’s radiopharmaceutical platform is unique in its use of copper-based payloads, which the biotech claims can deliver higher doses while also being safer. #seriesb #radiopharma #biospace.

Let’s celebrate the rising stars of biotech and pharma! BioSpace's 40 Under 40 honors emerging leaders making a real impact. Nominate a life sciences leader today:. #biotech #lifescineces #biospace40under40 #biospace

After “issues” with a batch of its investigational antibody briquilimab “confounded” the readout of Jasper Therapeutics’ Phase Ib/IIa BEACON study in chronic spontaneous urticaria (CSU), the California-based biotech is laying off approximately half of its staff. Get the details.

The deal gives @AstraZeneca's rare disease unit Alexion access to specialized capsids developed by the Japanese biotech JCR Pharmaceuticals for use in up to five of Alexion’s gene therapies. #genetherapy #biospace .

In the second biggest acquisition of the year, @Merck gains the commercial COPD drug Ohtuvayre, which could help offset the loss of revenue when Keytruda’s patent expires later this decade. #acquisition #COPD #biospace.

The high court’s order blocks a May decision by a California court that temporarily blocked the efforts of Health Secretary Robert F. Kennedy Jr. to drastically reduce the size of his agency’s workforce. #HHS #supremecourt #biospace.

The @US_FDA will allow a new dosing schedule for @EliLillyandCo's Alzheimer’s drug Kisunla that could lessen a known side effect of the monoclonal antibody drug class that has led to several deaths. #FDA #alzheimers #biospace.