Heng-Chang Chen
@BhiveLaboratory
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Principal Investigator @PORT_Wroclaw. Former @CRGenomica & @IGH_MTP. Quantitative Virology | Genome Informatics | Network Biology | Bioinformatics
Wrocław, Poland
Joined April 2022
📢A full 4-year funded #postdoc position opening in our lab. Those who are motivated in studying #HIV (antisense #RNA) at coordinates with #chromatin biology, #epigenetic & #epitranscriptimcs apply here 📩
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Developed by two Nobel Prize laureates, mRNA technology was used to create COVID-19 vaccines in a remarkably short timeframe. This innovative technology has opened up new possibilities of developing vaccines against influenza, zika and the human immunodeficiency virus (HIV).
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Today we had a computational virology workshop with Profs. Veronika Bernhauerova (Charles University Czechia) and Bartek Lisowski (Jagiellonian University Krakow, @SpyrosLytras (Univ Tokyo) and Cedric Tan (UCL Crick Institute). 4 hours of chit chat and coming up with ways to
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The first really big piece of research coming out of our Singaporean lab, this is Fadi's work @biofadialnaji , started in Chris Brooke's lab and completed here, over a four year period. Fadi serially passaged Flu over 80 times in conditions favouring defective genomes. He
biorxiv.org
The substantial genetic diversity generated during influenza A virus replication facilitates both evasion of pre-existing host immunity and cross-species emergence. A major contributor to this...
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Hidden DNA complexities revealed by new 3D genome mapping tool. Study in @JMDiagn details how technology could transform how we diagnose and treat genetic diseases. https://t.co/LVv1RIh2bm
#Genomics #GeneticTesting #PrecisionMedicine
@ASIPath
@AMPath
elsevier.com
Study on a powerful new technology in Elsevier’s Journal of Molecular Diagnostics highlights potential for better diagnosis & treatment of genetic diseases
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Why fundamental research is fundamental to progress, seeding major breakthroughs Editorial @Nature this week And 7 basic science discoveries that changed the world https://t.co/0YrKabc7ff
https://t.co/SM11QSJhWz
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I am often asked what the one skill is that young scientists should work on the most. My answer: your storytelling via presentations. The better you present, the more your ideas travel, the more doors open, and the more people want to work with you. A few tips: Have one clear
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I had a great time at #RNA Biology and Medicine Symposium in Krakow🧬 Very looking forward to the next meeting in Krakow, Autumn 2027 @MCB_UJ @magdamaslon @GlattSebastian @MCarmoFonseca @CieslaMaciej @JemielityLab @monika_piwecka
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This review provides an overview of the Hidden Markov model, outlining its fundamental concepts & corresponding algorithms, and examines their applications in modern #Bioinformatics, thereby fostering a deeper understanding of HMM. #OpenAccess: https://t.co/zOBfspNay1
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📢I'm excited to announce that my latest review is out at the Journal of Translational Medicine! Interested in knowing how #networkbiology can help with finding #biomarker targeting the #HIV reservoir? Read my review 👉
translational-medicine.biomedcentral.com
In the “omics” era, studies often utilize large-scale datasets, eliciting the overall functional machinery of a network’s organization. In this context, determining how to read the enormous number of...
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Our work "Aquarius helicase facilitates HIV-1 integration into R-loop enriched genomic regions," is out in @NatureMicrobiol
https://t.co/7wj0ra5f7U
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Feeling awed and a bit starstruck that @ScienceMagazine decided to run a book review on #LabworkToLeadership!! Thank you to @JonathanLWai for authoring the review!
science.org
A chemist offers actionable leadership advice to principal investigators
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"Immigrants and foreigners have always been an indispensable part of our country, including its great record in scientific research; eight of the 10 Nobel science-winners here today are U.S. citizens, but four of us are immigrants or children of immigrants." In his Nobel Prize
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📢We're excited to announce that our latest paper is out at Computational and Structural Biotechnology Journal 🎊Curious about how #HIV antisense RNAs influence its stochastic transcription? Please look 👉
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New preprint available! We introduced PLANT, an AI predicting the antigenicity of seasonal influenza viruses based on HA sequences. PLANT enables the direct creation of antigenic maps from sequences, highlighting differences between virus strains. 1/n https://t.co/Kp0i8vSIPd
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Piękne: cielesna mapa emocji. Na łamach „PNAS” przedstawiono fenomenalną matrycę ukazującą aktywację (ciepłe kolory) oraz dezaktywację (zimne kolory) różnych obszarów ciała pod wpływem określonych emocji. Ze wszystkich ocenianych emocji, jedynie szczęście wiąże się ze
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Dear all, We are starting an exciting project with @ClmentCarr5 in Paris, France. A fully funded PhD position is available in my group @VetmeduniVienna Please help us spreading the word! https://t.co/XSe1iMV3iA
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📢 3 postdoc (2x experimentalists; 1x bioinformatician) positions are open in our lab! If you are interested in working on #HIV coupled with #chromosome biology & #epigenetics, #bigdata, and pangenomics. Please apply 👉 https://t.co/08SUmatZRP
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