Panchenko lab
@AnnaPanchenko13
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Computational biology and biophysics @queensu, #epigenetics, #nucleosomes, #chromatin, #cancer.
Kingston, ON, Canada
Joined November 2020
Our study, in collaboration with Maria Aristizabal’s lab, predicted several histone cancer driver mutations with long-range allosteric effects and confirmed them experimentally:.
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Happy holidays, chromatiniers! Our new paper on histone cancer mutations and links to DNA repair:.
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Our new nucleosome positioning prediction method has been published. If you want to use it or see which nucleosomal features are deemed important:
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RT @DameLab: Nice to see our manuscript on bacterial histone HBb from Bdellovibrio online:.Different from eukaryoti….
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Check out a short paper by @DOstroverkhova and @ShengYiru5362 on pathogenicity predictors and their applicability to cancer:.
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Can next-generation pathogenicity predictors, like #AlphaMissense and VARITY, be effectively applied to cancer? Check out our study on a carefully designed experimental benchmark:
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RT @TeifLab: Excited to present the first ageing clock based on nucleosomics of cell-free DNA (cfDNA)! ✅ Nucleosome….
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Check out our new study of nucleosome positioning using deep residual networks.
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RT @MusselmanLab: Happy to share this just out in eLife (full text to follow soon) 👇This was a really great collaboration with @epicypher a….
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RT @LindorffLarsen: Happy to share the publication of our paper in @Nature. Conformational ensembles of the human intrinsically disordered….
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Our work on the identification of new pioneer transcription factors is out, in collaboration with @YunhuiP @DavidLandsman @TeifLab .
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Congratulations, Bing-Rui!.
Latest paper from our lab is out today @NatureSMB, once again led by Tengfei and Ruifang. Want to see how native nucleosome is manipulated by transcription factors? Check it out:
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RT @MusselmanLab: Interested in the genome and attending #bps24? Join the MGO subroup and attend our symposium on Saturday which includes t….
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RT @CellReports: DNA polymerase ε and δ variants drive mutagenesis in polypurine tracts in human tumors
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POLE variants promote genome-wide mutations in polypurine tracts - check out our paper by @DOstroverkhova in collaboration with Polina Shcherbakova's lab.
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RT @schlicklab: Read my latest #research [ on #Chromatin, #Genome, #Simulation, #HiC, #reconstruction, #Mesoscale,….
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RT @MusselmanLab: ✨Please joins us for the @BiophysicalSoc MGO Subgroup sponsored webinar on Tue Aug 1st at 12pm ET for two great talks!✨ @….
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