Almorò
@Almoro_Scarpa
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Population genetics & transposable elements 🧬
Vienna
Joined October 2023
Our work is finally out! Two TEs that triggered a cascade of invasion after introduction to cosmopolitan species of Drosophila. @Almoro_Scarpa @r_pianezza @KoflerRobert are such a pleasure to work with.
nature.com
Nature Communications - Horizontal transfer of genetic material in eukaryotes has rarely been documented over short evolutionary timescales. Here, the authors show that two transposable elements,...
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Super proud - our new work about two troublesome TEs spreading into several Droso species in just a few decades; it was so much fun to work with the amazing @r_pianezza @Almoro_Scarpa @signor_molevol
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Struggling to find a reliable and up-to-date repeat library for your organism of interest? With GenomeDelta, you might not need one anymore to discover cool TE families! Check out our latest publication in @GenomeBiology: https://t.co/axCPoyLH9J
genomebiology.biomedcentral.com
We present GenomeDelta, a novel tool for identifying sample-specific sequences, such as recent transposable element (TE) invasions, without requiring a repeat library. GenomeDelta compares high-qua...
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Incredibile conference! A lot of fun and a lot of great talks and posters on TEs at #cshlTE24 🧬
@Almoro_Scarpa & colleagues in @KoflerRobert Lab identified multiple transposons horizontally introduced in Drosophila over the past century, underscoring the promiscuity of TEs and their ability to spread worldwide in a matter of years. Amazing ‼️ #cshlTE24
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New lab paper out on bioRxiv! Transposons sometimes preferentially jump into piRNA clusters, but is it ever to their advantage? @fan_of_gpu simulated TE invasions and found that its never good for the TE! @KoflerRobert @Almoro_Scarpa
https://t.co/XjMXz46Hth
biorxiv.org
In our current understanding of transposable element (TE) invasions TEs move freely until they accidentally insert into a piRNA cluster. They are then silenced by the production of piRNA cognate to...
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Transposable elements invasions are tricky to identify, if you don't know the sequence of the TE. With our new tool -GenomeDelta- we provide a solution, which already helped us to find 3 new TE invasions in D. melanogaster (1) https://t.co/nirlqad1uD
biorxiv.org
To evade repression by the host defense, transposable elements (TEs) are occasionally horizontally transferred (HT) to naive species. TE invasions triggered by HT may be much more abundant than...
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Super excited my first chapter is out now in @MolBioEvol! Thanks to reviewers and editor, we validated our genome-wide inferences with #DECUB in light of gene-specific heterogeneities on mutation biases and codon usage. 1/4 https://t.co/mRGPsXWN4v
academic.oup.com
Abstract. Different frequencies amongst codons that encode the same amino acid (i.e. synonymous codons) have been observed in multiple species. Studies foc
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Looking for a #PhDposition in #EvolutionaryBiology? Then consider applying to this position: https://t.co/aCJdlEoPqr The project aims to develop phylogenetic methods to help us assess the prevalence and impact of gene flow during species divergence from phylogenomic data.
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Our new pre-print is out! Grateful to @Almoro_Scarpa, @signor_molevol and @KoflerRobert for their precious collaboration. Unveiling the complete invasion history of D. mel: three horizontal transfers of TEs in the last 30 years https://t.co/sBRMwBmk73
biorxiv.org
Transposable elements (TEs) are repetitive sequences capable of mobilizing within genomes, exerting significant influence on evolution throughout the tree of life. Using a novel approach that does...
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This paper was the beginning of an amazing journey, we are still discovering more and more about TEs in D. mel. If you are curious to know more, eiher wait for our next paper or you can listen to @KoflerRobert at the next @Dros_EU meeting for a sneak peek 🤫 4/4🧵
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Check out this striking comparison: mapping reads from ancient genomes onto those TEs! 🙀 This sashimi plot 🍣 shows how there was nothing similar to 412 and Opus. For Blood, the story is a bit different, if you are curious check out the paper 😉 3/4🧵
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In museum samples collected in the early 19 ͭ ͪ century, 412, Blood and Opus are completely absent, but present in all samples from 1933 onwards. 2/4🧵
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🚀Our latest paper in @PNASNews! https://t.co/sAMmtDrslZ We found that 3 LTR-retrotransposons 🧬 (412, Blood and Opus) invaded D. mel genome in the 19 ͭ ͪ century! Thanks to my fantastic collaborators @KoflerRobert, @r_pianezza, and @filwierz. #te #dmel #genetics 1/4🧵
pnas.org
Transposable element invasions have a profound impact on the evolution of genomes and phenotypes. It is thus an important open question how often s...
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A novel transposable element 🧬 in D. mel 🪰, check it out!
I'm glad to share my first publication, out now in @PLOSGenetics! "Spoink, a LTR retrotransposon, invaded D. melanogaster populations in the 1990s" A special collaboration with my co-author @Almoro_Scarpa, @signor_molevol and @KoflerRobert. https://t.co/6E02OZLJIg
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Dear friends of transposons: Genome Biology launched a special collection on 'TEs in genome evolution' with me and Juergen Schmitz as guest editors. We look forward to receiving your exciting new work by Dec 21 :) please RT
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yeeii very happy - our new work is out: P-element invasions could get out of (host) control - special thanks to the reviewers, in retrospect the comments were super helpful
pubmed.ncbi.nlm.nih.gov
To prevent the spread of transposable elements (TEs), hosts have developed sophisticated defense mechanisms. In mammals and invertebrates, a major defense mechanism operates through PIWI-interacting...
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How did we lose our tail? A simple question.. but it wasn't really asked before! We discovered a plausible scenario for the genetic mechanism that led to tail loss. Amazing that such a big change may have been caused by such a small genetic event. https://t.co/0ZR8aH23PJ
@BoXia7
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We start the #EEcourse23 with an introductory lecture to Experimental Evolution + case studies by @henriqueteoton2
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📅 Less than a week left until the EE course starts at @PopGenVienna! 📸 Full schedule below ❓More details and further updates: https://t.co/HELhzwGF8j
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It has been many years since the paper on 'The Spandrels of San Marco,' and yet people have not abandoned the adaptationist program. It's refreshing to come across a paper like this! #NonAdaptiveForcesAreCool
We have a new preprint up. This one is a hypothesis paper, addressing one of the bigger unanswered questions that people have been asking me for the last 15 years: why has complex multicellularity only evolved in eukaryotes, never in prokaryotes? 1/33
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