AI🤖 x Medicine💊 Papers
@AiMedicinePaper
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🤖💊 Exploring and sharing the latest research papers on innovative pharmaceuticals and AI-driven drug development. #ArtificialIntelligence #Biotechnology
Joined September 2025
Gemini要約🤖ファージ療法の耐性・特異性課題に対し、遺伝子工学で結合能力を改変。抗菌性物質を運ぶ遺伝子治療ベクター化を提案し、AI活用による未来のファージ設計の可能性を論じる。
🤖 Enhancing phage therapy through synthetic biology and genome engineering. Current opinion in biotechnology(2021) https://t.co/GCrGRVd2et
@grok summary⬇️ #GenomeEngineering
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🤖 Enhancing phage therapy through synthetic biology and genome engineering. Current opinion in biotechnology(2021) https://t.co/GCrGRVd2et
@grok summary⬇️ #GenomeEngineering
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Gemini要約💊頭頸部扁平上皮がん(HNSCC)治療の最新動向を解説。ネオアンチゲンを標的としたワクチンや養子細胞療法、免疫チェックポイント阻害剤との併用による新たな免疫療法の可能性と将来展望に注目。
💊 Immunotherapeutic Strategies for Head and Neck Squamous Cell Carcinoma (HNSCC): Current Perspectives and Future Prospects. Vaccines(2022) https://t.co/y172b1cVux
@grok summary⬇️ #Immunotherapy
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💊 Immunotherapeutic Strategies for Head and Neck Squamous Cell Carcinoma (HNSCC): Current Perspectives and Future Prospects. Vaccines(2022) https://t.co/y172b1cVux
@grok summary⬇️ #Immunotherapy
mdpi.com
Neoantigens are abnormal proteins produced by genetic mutations in somatic cells. Because tumour neoantigens are expressed only in tumour cells and have immunogenicity, they may represent specific...
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Gemini要約🔬AAV遺伝子治療は有望だが、課題克服のため新規カプシドを工学的に改良。構造設計、指向性進化、機械学習で効率・免疫原性・組織特異性を向上させ、臨床応用を加速する。
🔬 Advances in AAV capsid engineering: Integrating rational design, directed evolution and machine learning. Molecular therapy : the journal of the American Society of Gene Therapy(2025) https://t.co/Hm48CuBsZ1
@grok summary⬇️ #CRISPR #GeneEditing
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🔬 Advances in AAV capsid engineering: Integrating rational design, directed evolution and machine learning. Molecular therapy : the journal of the American Society of Gene Therapy(2025) https://t.co/Hm48CuBsZ1
@grok summary⬇️ #CRISPR #GeneEditing
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Gemini要約💻AAV遺伝子治療の性能向上に、計算手法によるカプシド工学が重要。構造生物学とAI/MLなどの先進計算ツールが、より効果的で個別化されたAAVベクター設計の可能性を広げる。
💻 Structural studies of Parvoviridae capsid assembly and evolution: implications for novel AAV vector design. Frontiers in artificial intelligence(2025) https://t.co/toUI5yTD1l
@grok summary⬇️ #GeneTherapy #AAV
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💻 Structural studies of Parvoviridae capsid assembly and evolution: implications for novel AAV vector design. Frontiers in artificial intelligence(2025) https://t.co/toUI5yTD1l
@grok summary⬇️ #GeneTherapy #AAV
frontiersin.org
Adeno-associated virus (AAV) vectors have emerged as powerful tools in gene therapy, potentially treating various genetic disorders. Engineering the AAV caps...
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Gemini要約💊細胞老化が心不全の原因となるが、AMIにおける診断マーカー研究は未報告。本研究はバイオインフォマティクスでAMIの細胞老化関連主要遺伝子メカニズムを探求する。
💊 Identification and validation of key genes associated with cell senescence in acute myocardial infarction. Frontiers in cardiovascular medicine(2025) https://t.co/BzrCqyz38H
@grok summary⬇️ #RNAtherapy
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💊 Identification and validation of key genes associated with cell senescence in acute myocardial infarction. Frontiers in cardiovascular medicine(2025) https://t.co/BzrCqyz38H
@grok summary⬇️ #RNAtherapy
frontiersin.org
IntroductionCellular senescence can cause heart failure. However, studies on diagnostic markers related to cellular senescence in acute myocardial infarction...
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Gemini要約🌱転移性前立腺がんの患者層別化と薬剤耐性モニタリングに向け、mRNAベースのin situパドロックプローブを用いたCTC包括的特性評価の有用性を実証。
🌱 Advanced single-cell and spatial analysis with high-multiplex characterization of circulating tumor cells and tumor tissue in prostate cancer: Unveiling resistance mechanism… Biomarker research(2024) https://t.co/gl4a57J0JZ
@grok summary⬇️ #mRNA #Vaccine
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🌱 Advanced single-cell and spatial analysis with high-multiplex characterization of circulating tumor cells and tumor tissue in prostate cancer: Unveiling resistance mechanism… Biomarker research(2024) https://t.co/gl4a57J0JZ
@grok summary⬇️ #mRNA #Vaccine
link.springer.com
Biomarker Research - Metastatic prostate cancer is a highly heterogeneous and dynamic disease and practicable tools for patient stratification and resistance monitoring are urgently needed. Liquid...
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Gemini要約🌱再発性膠芽腫患者において、MLモデルでMRIから推定される治療後の細胞質密度と細胞外液密度の変化が、腫瘍体積とは独立して生存率を予測する重要な指標となることを発見しました。
🌱 Radio-pathomic estimates of cellular growth kinetics predict survival in recurrent glioblastoma. CNS oncology(2024) https://t.co/PZbnAEbxrU
@grok summary⬇️ #Biopharma
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🌱 Radio-pathomic estimates of cellular growth kinetics predict survival in recurrent glioblastoma. CNS oncology(2024) https://t.co/PZbnAEbxrU
@grok summary⬇️ #Biopharma
tandfonline.com
Aim: A radio-pathomic machine learning (ML) model has been developed to estimate tumor cell density, cytoplasm density (Cyt) and extracellular fluid density (ECF) from multimodal MR images and auto...
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Gemini要約🔬神経穿通なしで深部神経束を記録・刺激できる、低侵襲・電池不要・ワイヤレスPNSインターフェースを開発。ウェアラブルなAI搭載機器と連携し、麻痺や切断患者の神経疾患治療に貢献する。
🔬 Fascicle-Selective Ultrasound-Powered Bidirectional Wireless Peripheral Nerve Interface IC. IEEE transactions on biomedical circuits and systems(2023) https://t.co/ofeVGxaRpq
@grok summary⬇️ #Biopharma
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🔬 Fascicle-Selective Ultrasound-Powered Bidirectional Wireless Peripheral Nerve Interface IC. IEEE transactions on biomedical circuits and systems(2023) https://t.co/ofeVGxaRpq
@grok summary⬇️ #Biopharma
ieeexplore.ieee.org
This paper presents an innovative, minimally invasive, battery-free, wireless, peripheral nervous system (PNS) neural interface, which seamlessly integrates a millimeter-scale, fascicle-selective...
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Gemini要約🔬機械学習で最適化された脂質ナノ粒子(LNP)が、炎症性ミクログリアへmRNAを効率的に送達し、炎症反応を抑制。神経炎症性疾患のmRNA治療に新たな道を開く可能性を示しました。
🔬 Machine learning-assisted design of immunomodulatory lipid nanoparticles for delivery of mRNA to repolarize hyperactivated microglia. Drug delivery(2025) https://t.co/aC4YYRkvXx
@grok summary⬇️ #mRNA #Vaccine
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🔬 Machine learning-assisted design of immunomodulatory lipid nanoparticles for delivery of mRNA to repolarize hyperactivated microglia. Drug delivery(2025) https://t.co/aC4YYRkvXx
@grok summary⬇️ #mRNA #Vaccine
tandfonline.com
Regulating inflammatory microglia presents a promising strategy for treating neurodegenerative and autoimmune disorders, yet effective therapeutic agents delivery to these cells remains a challenge...
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Gemini要約🤖Brugada症候群の診断は難しく致死リスクが高い。AIは専門医の目を超える精度で心電図パターンを検出し、未分類遺伝子変異も特定。診断能力で専門医を凌駕する。
🤖 Artificial intelligence for Brugada syndrome diagnosis and gene variants interpretation. American journal of cardiovascular disease(2025) https://t.co/4C2pL1GfEF
@grok summary⬇️ #RegenerativeMedicine
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🤖 Artificial intelligence for Brugada syndrome diagnosis and gene variants interpretation. American journal of cardiovascular disease(2025) https://t.co/4C2pL1GfEF
@grok summary⬇️ #RegenerativeMedicine
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