Aaron Kler
@AaronKler
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NHS Clinician | RCS Fellow|Colorectal Surgery| Abdominal wall reconstruction| ππΏββοΈπ π β½οΈ π₯πποΈ
Manchester, England
Joined July 2015
Delighted to have won the @RSMcoloproct John of Arderne medal ποΈ on my PhD researching metabolomic changes associated with radiation in locally advanced rectal cancer. Huge shout out to my supervisors @rickdunnblade @MSciacovelliLab & @dalevim for their supportπππ§ͺπ·!
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Great talks at #SILASC by the #BRIDGES team yesterday Huge shout out to @docdondons & @Mr_A_GT with some great research from their PhDsπ₯π₯π₯ππ€π¨π½ββοΈπ©π½ββοΈ
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Excited (read nervous!) for this β¬οΈ
Exciting news! Our Clinical Innovation Lead, Dr @VidehaSharma will deliver a @TEDx talk at @Hult_Business on Feb 24! π Join the livestream to explore limitless opportunities for change through design thinking in healthcare: https://t.co/MeuNFxSMXE
#TEDx #HealthcareInnovation
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Organ Preservation and Survival by Clinical Response Grade in Patients With Rectal Cancer Treated With Total Neoadjuvant Therapy: A Secondary Analysis of the OPRA Randomized Clinical Trial | Oncology | JAMA Network Open | JAMA Network
jamanetwork.com
This secondary analysis of a randomized clinical trial assesses organ preservation and survival outcomes for patients with rectal cancer according to a 3-tier clinical tumor response grading schema.
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Important secondary analysis of the OPRA trial with a median f/u of 4 years. This provides important details from a landmark study, and can help guide patient counseling. Of note, it's not broken down to compare induction TNT to consolidation TNT. My analysis is long-winded,
Organ Preservation and Survival by Clinical Response Grade in Patients With Rectal Cancer Treated With Total Neoadjuvant Therapy: A Secondary Analysis of the OPRA Randomized Clinical Trial | Oncology | JAMA Network Open | JAMA Network
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keep your ears open for clinical MD/PhD opportunities in colorectal disease/surgery opening soon in the mersey area. Message for details @dalevim
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Happy 2024! Thrilled to share that my first-author paper, stemming form my PhD project, has been published @JMolBiol. Feel free to reach out for any questions. Thank you to my supervisors for helping out and making this possible. https://t.co/5eoAQcAH6G
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Is the risk of distant metastasis higher in those rectal cancer pts undergoing surgery for local regrowth compare to those undergoing upfront surgery for near complete response after chemoradiation? Find out in #DCRJournal: https://t.co/SjMTBdoL7W
@Swexner @me4_so @ACPGBI
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Just saw this rectal cancer study in @JAMAOnc β lots to digest. Despite absolute 50% drop (87% to 37%) in use of neoadjuvant RT for lower risk (cT1-3, N0-1, MRF-) rectal cancers from 2011 to 2016, no difference in local recurrence & survival improved. https://t.co/fbjPyAvATu
jamanetwork.com
This cross-sectional study examines the association of decreased use of neoadjuvant radiotherapy with cancer-related outcomes and overall survival.
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π₯The EAGLE study is out! Evaluation of a quality improvement intervention to reduce anastomotic leak following right colectomy (EAGLE): pragmatic, batched stepped-wedge, cluster-randomized trial in 64 countries β‘οΈ https://t.co/9mzJWs7tMZ By the ESCP EAGLE Safe Anastomosis
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I remember some radiologists asking for my GMC number and asking me to type on the request βI take responsibility if contrast causes AKIβ as a F2, to get a contrast CT scan done. Itβs taken a long time despite the evidence being there for years.
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A nice concise summary of ventral hernia practice
academic.oup.com
Ventral hernia repair has evolved into varied surgical options1β3 according to the classification as either primary hernia (umbilical, epigastric, Spigelia
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Time to start performing more elective resections for diverticulitis β¦.? https://t.co/3uumfEn26x
jamanetwork.com
This 2-year follow-up of the LASER randomized clinical trial evaluates quality-of-life outcomes among patients with recurring, complicated, or persistent painful diverticulitis following surgery vs...
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Correction: Doctors should not HAVE to strike. There, fixed it for you.
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Iβm shocked Junior Doctors are on a Β£14 hourly wage? I find that mind blowing, considering I wasnβt far behind that teaching Boxercise classes in the early noughties. Are you shocked by this? The Drβs pay that is, not the Boxercise? #JuniorDoctorsStrike
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just over a month until NW Advanced colorectal research day in the wonderful spine conference centre. Over half available tickets now sold. dont miss! Β£20 only for the day! https://t.co/L1I41BViyW
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This will become the norm rather than the exception - Effect of Prehabilitation on Postoperative Complications and Functional Capacity for Colorectal Cancer Surgery https://t.co/zvJC73pPWC?
@lawrenceleemd @SAGES_Updates @lianefeldman @FergaljFleming @ErasSociety
jamanetwork.com
This randomized clinical trial determines whether multimodal prehabilitation before colorectal cancer surgery can reduce postoperative complications and enhance functional recovery.
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